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purM from Burkholderia pseudomallei MSHR346

Victor ID 3668
Gene Name purM from Burkholderia pseudomallei MSHR346
Sequence Strain (Species/Organism) Burkholderia pseudomallei MSHR346
NCBI Gene ID 7888461
NCBI Protein GI 237813669
Locus Tag GBP346_A3446
Protein Accession YP_002898120.1
Other Database IDs UniProtKB-ID: C4KUE3_BURPS
UniRef100: UniRef100_A3MN88
UniRef90: UniRef90_A3MN88
UniRef50: UniRef50_Q5F973
UniParc: UPI0000440EAD
EMBL: CP001408
EMBL-CDS: ACQ98217.1
RefSeq_NT: NC_012695.1
ProtClustDB: PRK05385
Taxonomy ID 536230
Chromosome No I
Gene Starting Position 3328198
Gene Ending Position 3329253
Gene Strand (Orientation) -
Protein Name phosphoribosylformylglycinamidine cyclo-ligase
DNA Sequence 
>gi|237810278:3328198-3329253 Burkholderia pseudomallei MSHR346 chromosome I, complete genome
GTCAGACCACGACCGTCTGCGCCTCGCCTTCGCGGCTCGCGCGCACGGTGCCGATCTTCCATACCTGCTC
GCCCGCGTCGGCCAGTTGGCGGAGCGCATCGTCCGCGTCGGCGGCCGACACGATCACGGCCATCCCGATC
CCGCAGTTGAACACGCGGTGCATCTCCGCATCGGCGACGCCGCCGTGCTGCTGCAGCCACTGGAACAGCG
GCGGCAGCGGCCATGCGTGCTGGTCGAGTTCGGCCGTGAGGCCGTCGCGCAGCACGCGCGGAATGTTCTC
GACGAGGCCGCCGCCCGTGATGTGCGCCATTCCCTTCACCGCGATCTTCTCCATCAGCGCGAGGAGCGGC
TTCACGTAGATGCGCGTCGGCGCCATCAGCGCGTCGGCGAGCGAGCGGCCGTGGAAATCGGCCGACAGGT
CCGGATTCGCGCGCTCGATGATCTTGCGCACGAGCGAGAAACCGTTCGAATGGATGCCGCTCGACGCGAG
GCCCAGCACGACGTCGCCCTCGGCGATCGTGCTGCCGTCAATGATCTTGCTCTTCTCGACCGCGCCGACC
GCGAAGCCCGCCAGATCGTATTCGCCGTCCGGGTACATGCCCGGCATCTCGGCCGTCTCGCCGCCGATCA
GCGCGCAGCCCGCCAGCTCACAGCCCGTCGCGATGCCCTTGACGACGGTCGCGGCCGTCTCGACGTCGAG
CTTGCCGCACGCGAAGTAGTCGAGGAAGAACAGCGGCTCGGCGCCCTGCACGAGAATGTCGTTTACGCTC
ATCGCGACGAGATCCTGGCCGACCGTATCGTGTTTGTTCAGATGAAACGCGAGCTTGAGCTTCGTGCCGA
CGCCGTCCGTGCCCGATACGAGCACGGGCTCCCGGTACTTCTTCGGCACCTCGAACAGCGCGCCGAACCC
GCCGATGCCGCCGAGCACGCCGTCGCGCAGCGTTTTCTTCGCAAAGGGCTTGATCTTGTCGACGAGCGCG
TCGCCCGCGTCGATGTCGACGCCCGCGTCACGGTAGGACAGGCCCTGGGCGTCGGGAGCGGATTTCGGAG
GATTCA
Protein Sequence 
>gi|237813669|ref|YP_002898120.1| phosphoribosylaminoimidazole synthetase [Burkholderia pseudomallei MSHR346] MNPPKSAPDAQGLSYRDAGVDIDAGDALVDKIKPFAKKTLRDGVLGGIGGFGALFEVPKKYREPVLVSGTDGVGTKLKLAFHLNKHDTVGQDLVAMSVNDILVQGAEPLFFLDYFACGKLDVETAATVVKGIATGCELAGCALIGGETAEMPGMYPDGEYDLAGFAVGAVEKSKIIDGSTIAEGDVVLGLASSGIHSNGFSLVRKIIERANPDLSADFHGRSLADALMAPTRIYVKPLLALMEKIAVKGMAHITGGGLVENIPRVLRDGLTAELDQHAWPLPPLFQWLQQHGGVADAEMHRVFNCGIGMAVIVSAADADDALRQLADAGEQVWKIGTVRASREGEAQTVVV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: purM mutant is attenuated in mice (Pilatz et al., 2006).
COG COG0150F, under F: Nucleotide transport and metabolism
References
Pilatz et al., 2006: Pilatz S, Breitbach K, Hein N, Fehlhaber B, Schulze J, Brenneke B, Eberl L, Steinmetz I. Identification of Burkholderia pseudomallei genes required for the intracellular life cycle and in vivo virulence. Infection and immunity. 2006; 74(6); 3576-3586. [PubMed: 16714590].