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rpoE

Victor ID 3673
Gene Name rpoE
Sequence Strain (Species/Organism) Burkholderia pseudomallei MSHR346
NCBI Gene ID 7889774
NCBI Protein GI 237813202
Locus Tag GBP346_A2967
Genbank Accession CP001408
Protein Accession YP_002897653
Other Database IDs UniProtKB-ID: C4KRI8_BURPS
UniRef100: UniRef100_C4KRI8
UniRef90: UniRef90_C4KRI8
UniRef50: UniRef50_Q06198
UniParc: UPI000043B3A3
EMBL: CP001408
EMBL-CDS: ACQ96242.1
RefSeq_NT: NC_012695.1
OMA: MSLISRY
ProtClustDB: PRK09652
Taxonomy ID 536230
Chromosome No I
Gene Starting Position 2891049
Gene Ending Position 2891648
Gene Strand (Orientation) -
Protein Name RNA polymerase sigma factor RpoE
Protein pI 5.19
Protein Weight 21601.07
Protein Length 199
Protein Note Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response
DNA Sequence 
>gi|237810278:2891049-2891648 Burkholderia pseudomallei MSHR346 chromosome I, complete genome
CTTACCAGCGCCTGCCTTCCGGCGTATCGAGCAGCGGCCGCAATTTTGCCGCGATCGCCTCGCGGGCGCG
AAAGATCCGCGAGCGAACGGTGCCGATCGGGCAACCCATCATCTCCGCGATCTCTTCGTAGCTCAGACCT
TCGATCTCGCGCAGCGTGATGGCCGTTCGCAACTCTTCCGGCAACAGCGCCATCGCGGCGTTGACCGTTT
GGGCGATCTGCTTGCTCATCAACATCGACTCAGGCGTGTTGATATCCCTTAGTTGGTCCGCGTCGGAGAA
AGTTTCAGCCTCTTCGGCGTCCGCGTCGGTGGACGTGGGCGCCCGGCGCCCCTGGGTCGCAAGGTAGTTC
TTCGCCGTATTGACGGCAATCCGGTACAACCACGTGTAGAACGCCGACTCGCCGCGAAACTGCGGCAACG
CGCGATACGCCTTGATGAACGCGTCCTGGGCCACGTCCTCGACCTCCGCGGGATCCCGCACGAGGCGCGA
GATCAGCCGGATGATCTTGCGGTGGTATTTGGAGACCAGGAGTTCGAACGCCGCCTTGTCGCCATTCTGT
ACGCGTTCGACCAGTACCTGATCGATTTCTTTTTCACTCA
Protein Sequence 
>gi|237813202|ref|YP_002897653.1| RNA polymerase sigma factor RpoE [Burkholderia pseudomallei MSHR346]
MSEKEIDQVLVERVQNGDKAAFELLVSKYHRKIIRLISRLVRDPAEVEDVAQDAFIKAYRALPQFRGESA
FYTWLYRIAVNTAKNYLATQGRRAPTSTDADAEEAETFSDADQLRDINTPESMLMSKQIAQTVNAAMALL
PEELRTAITLREIEGLSYEEIAEMMGCPIGTVRSRIFRAREAIAAKLRPLLDTPEGRRW
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: rpoE mutant is attenuated in mice (Thongboonkerd et al., 2007).
COG COG1595K, under K: Transcription
References
Thongboonkerd et al., 2007: Thongboonkerd V, Vanaporn M, Songtawee N, Kanlaya R, Sinchaikul S, Chen ST, Easton A, Chu K, Bancroft GJ, Korbsrisate S. Altered proteome in Burkholderia pseudomallei rpoE operon knockout mutant: insights into mechanisms of rpoE operon in stress tolerance, survival, and virulence. Journal of proteome research. 2007; 6(4); 1334-1341. [PubMed: 17346071].