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BPSL0872

Victor ID 2006
Gene Name BPSL0872
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3093782
NCBI Protein GI 53718511
Locus Tag BPSL0872
Genbank Accession BX571965
Protein Accession YP_107497
Other Database IDs UniProtKB-ID: Q63WL9_BURPS
UniRef100: UniRef100_A3NS84
UniRef90: UniRef90_Q3JVB5
UniRef50: UniRef50_Q3JVB5
UniParc: UPI000043ADB2
EMBL: BX571965
EMBL-CDS: CAH34864.1
RefSeq_NT: NC_006350.1
GenomeReviews: BX571965_GR
KEGG: bps:BPSL0872
NMPDR: fig|272560.3.peg.3200
HOGENOM: HBG731814
OMA: MLKITFP
ProtClustDB: CLSK930442
BioCyc: BPSE272560:BPSL0872-MONOMER
Taxonomy ID 272560
Chromosome No 1
Gene Starting Position 1011780
Gene Ending Position 1013330
Gene Strand (Orientation) +
Protein Name MviN-like protein
Protein pI 10.82
Protein Weight 51133.79
Protein Length 516
Protein Note Similar to Ralstonia solanacearum probable transmembrane protein rsc2557 or rs00736 SWALL:Q8XWB7 (EMBL: AL646070) (517 aa) fasta scores: E(): 2.3e-128, 65.69% id in 516 aa, and to Yersinia pestis putative membrane protein ypo2043 SWALL:Q8ZEW0 (EMBL: AJ414151) (511 aa) fasta scores: E(): 9.6e-97, 52.7% id in 518 aa, and to Escherichia coli, and Escherichia coli O157:H7 virulence factor MviN homolog b1069 or z1707 or ecs1447 SWALL:MVIN_ECOLI (SWALL:P75932) (511 aa) fasta scores: E(): 2.6e-96, 52.23% id in 515 aa
DNA Sequence 
>gi|53717639:1011780-1013330 Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence
CATGAATCTATTCCGAGCCCTGCTGACGGTCAGCGGCTTCACGCTGCTGTCGCGCGTGACCGGACTGGCC
CGTGAGACGCTGATCGCCCGCGCGTTCGGCGCCAGTCAATTCACCGACGCGTTCTACGTCGCATTCCGTA
TTCCGAACCTGCTGCGCCGGCTGTCCGCCGAAGGGGCGTTTTCGCAGGCGTTCGTGCCGATTCTCGCCGA
GTTCAAGAATCAAAAAGGGCACGATGCGACGAAGGCGCTGGTCGACGCGATGTCGACCGTGCTCGCGTGG
GCGCTCGCGCTCCTGTCGCTCGCGGGGATCGCAGGCGCGTCGTGGGTGGTGTTCGCGGTCGCGTCGGGGC
TGCGCACGGACGGCCAGGCGTTCCCGCTCGCCGTCGCGATGACGCGGATCATGTTCCCGTACATCGTGTT
CATTTCGCTCACCACGCTCGCGTCGGGCGTGCTCAACACGTACAAGCGTTTCTCGCTGCCGGCGTTCGCG
CCCGTGCTGCTGAACGTCGCGTTCATCGTCGCGGCGGTGTTCGTCGCGCCGCACCTGAAGGTGCCCGTCT
ATGCGCTCGCATGGGCGGTGATCGCGGGCGGCGCGCTGCAGTTCGCGGTGCAGTTGCCGGGGCTGAAGAA
GATCGACATGATGCCCGCGATCGGCGTGAATCCGCTGCGCGCGCTCGCGCACCCGGGCGTGAAGCGTGTG
CTGGCGAAGATGGTGCCCGCGACGTTCGCGGTGTCGGTCGCGCAACTGTCGCTCATCATCAATACGAACA
TCGCGTCGCGGCTCGGGCAGGGCGCCGTGTCGTGGATCAATTACGCGGACCGGCTGATGGAGTTTCCGAC
CGCGCTCCTCGGCGTCGCGCTCGGCACGATCCTGCTGCCGAGCCTGTCGAAGGCGCACGTCGACGCCGAT
TCGACCGAGTATTCGGCGCTCCTCGACTGGGGCCTGCGGGTCACGTTCCTGCTCGCGGCGCCGAGCGCGC
TCGCGCTGTTCTTCTTCGCCGAGCCGCTCACGGCGACGCTGTTCAATTACGGCAAATTCGACGCGCACAC
GGTCACGATGGTCGCGCGCGCGCTCGCGACGTACGGGATCGGCCTCGTCGGCATCATCCTCATCAAGATC
CTCGCACCCGGCTTCTATGCGAAGCAGGACATCAAGACGCCCGTGAAGATCGCGATCGGCGTGCTCGTCG
TCACGCAGTTGTCGAACTACGTGTTCGTGCCGATCATCGGCCACGCGGGGCTCACGCTGAGCATCGGCGT
GGGCGCGTGCCTGAACTCGCTGCTGCTCTTCATCGGGCTGCGCCGCCGCGGCATCTATCAGCCGTCGTCC
GGCTGGCTGCGCTTTTTCGCGCAGCTCGCGGGCGCCTCGCTCGTGCTCGCCGGCGTGATGCGCTGGCTCG
CGATCAACTTCGACTGGACCGCGATGCGCGCGGCGCCGCTCGAGCGGATCGCGCTGATGGCAGCCTGCCT
CGTTCTGTTCGCTGCACTATATTTCGGTATGTTGTGGCTGATGGGTTTCAAATACGCGTACTTCAGACGG
CGCGCCAAGTA
Protein Sequence 
>gi|53718511|ref|YP_107497.1| MviN-like protein [Burkholderia pseudomallei K96243]
MNLFRALLTVSGFTLLSRVTGLARETLIARAFGASQFTDAFYVAFRIPNLLRRLSAEGAFSQAFVPILAE
FKNQKGHDATKALVDAMSTVLAWALALLSLAGIAGASWVVFAVASGLRTDGQAFPLAVAMTRIMFPYIVF
ISLTTLASGVLNTYKRFSLPAFAPVLLNVAFIVAAVFVAPHLKVPVYALAWAVIAGGALQFAVQLPGLKK
IDMMPAIGVNPLRALAHPGVKRVLAKMVPATFAVSVAQLSLIINTNIASRLGQGAVSWINYADRLMEFPT
ALLGVALGTILLPSLSKAHVDADSTEYSALLDWGLRVTFLLAAPSALALFFFAEPLTATLFNYGKFDAHT
VTMVARALATYGIGLVGIILIKILAPGFYAKQDIKTPVKIAIGVLVVTQLSNYVFVPIIGHAGLTLSIGV
GACLNSLLLFIGLRRRGIYQPSSGWLRFFAQLAGASLVLAGVMRWLAINFDWTAMRAAPLERIALMAACL
VLFAALYFGMLWLMGFKYAYFRRRAK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: BPSLO872 (mviN) mutant displayed an increased LD50 value in the hamster infection model and a loss of the ability to invade human lung epithelial cells (Ling et al., 2006).
COG COG0728R, under R: General function prediction only
References
Ling et al., 2006: Ling JM, Moore RA, Surette MG, Woods DE. The mviN homolog in Burkholderia pseudomallei is essential for viability and virulence. Canadian journal of microbiology. 2006; 52(9); 831-842. [PubMed: 17110975].