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wzm

Victor ID 2008
Gene Name wzm
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3093941
NCBI Protein GI 53720414
Locus Tag BPSL2805
Genbank Accession BX571965
Protein Accession YP_109400
Other Database IDs UniProtKB-ID: Q63R68_BURPS
UniRef100: UniRef100_C4KUC8
UniRef90: UniRef90_C4KUC8
UniRef50: UniRef50_A0K4V3
UniParc: UPI00000B9460
EMBL: BX571965
EMBL-CDS: CAH36814.1
RefSeq_NT: NC_006350.1
GenomeReviews: BX571965_GR
KEGG: bps:BPSL2805
HOGENOM: HBG295825
OMA: GAFFFVH
ProtClustDB: CLSK834229
BioCyc: BPSE272560:BPSL2805-MONOMER
Taxonomy ID 272560
Chromosome No 1
Gene Starting Position 3352911
Gene Ending Position 3353693
Gene Strand (Orientation) -
Protein Name putative capsular polysaccharide export ABC transporter transmembrane protein
Protein pI 7.19
Protein Weight 26636.55
Protein Length 260
Protein Note Also known as bexBSimilar to Haemophilus influenzae capsule polysaccharide export inner-membrane protein BexB bexB SWALL:BXB2_HAEIN (SWALL:P19391) (265 aa) fasta scores: E(): 1.8e-44, 42.47% id in 259 aa. Identical to Burkholderia mallei putative ABC-2 transporter Wzm SWALL:Q9AI46 (EMBL: AF285636) (260 aa) fasta scores: E(): 6.2e-105, 100% id in 260 aa
DNA Sequence 
>gi|53717639:3352911-3353693 Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence
ATCATTCTGGCGTGACCTCACGACCCACGTCGCGAACCAGCGCGAGACCGACCAGAGACATCGCCAGGCA
AGCGCACGCCATATATCCGATATCATAATGTGCCGCGACGAGGCTGCCGAAGTACCCTTCGCGAAGCATT
TCGACTCCGTGCACCATGGGCAGCCACAGGACGATTTTTTGAAATGCCGGCGAAAGCCAATCCACCATGA
AGATGGCGCCCGATAGCGGAAACATCAGATAGGTCACCGGATGCCAAAGCTTCTCGACGAGCTCCGTCTT
CTCGCTTAACGCTCCAATGATGAAACCAAGCGACGCACCAAACCAGATAATCATGACCCAGGCAAACATC
ACCTCGAGAATATCCTCGGGATAGTCAACGAGGCCCAGCGCATGAAATGTAATCATCAACACGAAAAAGG
ATGCGGTATTACCGACCACCTCCAACAGAATACGAGCAATAAAAATATCTATGACCTTGACATTTCGGTG
ATACATCAGCGCCAAATTCGGCGTGACCGCCATACTGCACCGCCCGGGCATGTTTCGCCAAAGCAACACC
GTCGAATAGCCGGTCAAAGCAAACGCGGAAATAGGGAGATTCGACCCGTGAGTCGCTCCTGTCGCATTCC
AAAGAATGGTAATCCCGACCGTGAAGATCATCGGCTCGACAAATAGCCACAGGAATCCGATGTTGTGACG
CCCGTACCGGGTCAGGACTTCCCGCATCAGCAATGCGAATATCACTCTTCGCTGAACCGCCAACGATCGA
CCGAAATTTGTCA
Protein Sequence 
>gi|53720414|ref|YP_109400.1| putative capsular polysaccharide export ABC transporter transmembrane protein [Burkholderia pseudomallei K96243]
MTNFGRSLAVQRRVIFALLMREVLTRYGRHNIGFLWLFVEPMIFTVGITILWNATGATHGSNLPISAFAL
TGYSTVLLWRNMPGRCSMAVTPNLALMYHRNVKVIDIFIARILLEVVGNTASFFVLMITFHALGLVDYPE
DILEVMFAWVMIIWFGASLGFIIGALSEKTELVEKLWHPVTYLMFPLSGAIFMVDWLSPAFQKIVLWLPM
VHGVEMLREGYFGSLVAAHYDIGYMACACLAMSLVGLALVRDVGREVTPE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: wzm mutant is attenuated in mice (Cuccui et al., 2007).
COG COG1682GM, under G: Carbohydrate transport and metabolism; M: Cell wall/membrane/envelope biogenesis
References
Cuccui et al., 2007: Cuccui J, Easton A, Chu KK, Bancroft GJ, Oyston PC, Titball RW, Wren BW. Development of signature-tagged mutagenesis in Burkholderia pseudomallei to identify genes important in survival and pathogenesis. Infection and immunity. 2007; 75(3); 1186-1195. [PubMed: 17189432].