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BPSL2825

Victor ID 1996
Gene Name BPSL2825
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3091847
NCBI Protein GI 53720434
Locus Tag BPSL2825
Genbank Accession BX571965
Protein Accession YP_109420
Other Database IDs UniProtKB-ID: Q63R48_BURPS
UniRef100: UniRef100_A1V0U9
UniRef90: UniRef90_A1V0U9
UniRef50: UniRef50_A1V0U9
UniParc: UPI000043B508
EMBL: BX571965
EMBL-CDS: CAH36835.1
RefSeq_NT: NC_006350.1
GenomeReviews: BX571965_GR
KEGG: bps:BPSL2825
HOGENOM: HBG507440
OMA: VNYTYRL
ProtClustDB: CLSK931093
BioCyc: BPSE272560:BPSL2825-MONOMER
Taxonomy ID 272560
Chromosome No 1
Gene Starting Position 3376581
Gene Ending Position 3378599
Gene Strand (Orientation) -
Protein Name hypothetical protein
Protein pI 6.59
Protein Weight 66715.02
Protein Length 672
Protein Note Similar to Ralstonia solanacearum putative para-aminobenzoate synthetase component I protein PabB or rsc2633 or rs05772 SWALL:Q8XW42 (EMBL: AL646071) (626 aa) fasta scores: E(): 1.4e-57, 50.88% id in 676 aa, and to Neisseria meningitidis para-aminobenzoate synthetase component i/4-amino-4-deoxychorismate lyase, putative nmb1970 SWALL:Q9JXM6 (EMBL: AE002545) (593 aa) fasta scores: E(): 1e-42, 41.3% id in 661 aa, and to Neisseria meningitidis putative para-aminobenzoate synthase component I nma0477 SWALL:Q9JW99 (EMBL: AL162753) (598 aa) fasta scores: E(): 1.7e-42, 41.3% id in 661 aa, and to Rhizobium loti hypothetical protein Mlr3005 SWALL:Q98H70 (EMBL: AP003000) (381 aa) fasta scores: E(): 3.3e-30, 42.05% id in 321 aa
DNA Sequence 
>gi|53717639:3376581-3378599 Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence
CCTATCGCGGTGCCGCCGCGCCGGCGGCCCGCACGAGTTGCGCGGGCATCGCGCCGCGCAACGCGTTCGT
CAGCATCAGCGCGTCGGCGCGCAGCACGTCGTCCAGCGTCATTACACGCTCGGACGCCTGCCATGCCGGA
TCGTCGAGCAGCGCGCCGCGCATCACGCCCGGCAACACGCCCGACGACAGCGGCGGCGTGAACCAGCGCC
CGGCCAGCTTCACGAATACGCTCGTGCGCCCGCCTTCGGTCAATTCGCCGCGTTCGTTGAAGAACAGCAT
GTCGAACGCACCGCACGCCTGCGCGGCTTTCCACGCGCGATCGTAATCGGCGCGGCGCGTCGTCTTGTGC
GCGAGCAGGAAGTCGCCCGAGCGCATCGGCGCGAACCCGTGCTCGGGCGCGAGCAACACGGCCACCGCGG
CGCCCGCGAGCGGCGCGAGCGGCGCGGCCACGATGTCGAGCACGCCGTCCTTCGCGAGCGCGACGCGCAA
GCGATGCTCGCCGTCGCCGAGCTGCACGCAGCGCGCGCCGATGCGCTGCCTGGCCGCCGCTTCGTCGAAC
GCGAAGCCGAGCGCGTCGGCACTCGCGCGCAGCCGCGCGACATGGCGGTCGAGATGGCGCACGCCGGCGT
CACGCGTGGCGAGCATCGTCTCGAACAACTGGAAGCCGGGCTCGGCGTCGGTCAGGAAACGCGCCTTCAA
TTCGCACTCCGCGTATTCGTCGGCGGCAACGCTGTCGAGCACGATGCCCGCGCCGACGCCCATCGTGCCG
CGCCGCTCGCCGCCGGCCGACGGCGCGTCGAGCGTCAGCGTGCGGATCGCGACCGACAGGCAGAAATCGC
CGCACGCGCCGGCCGGGCTTGTCGCGCCGGCACGCTTCGACGCCTGCTTCGACGCGGTTTCGCCCGCGCA
TGCGCCATCCGACGCCGTGCCTGGGGACGAGCTCGCCGCACGCTCCGGCGCGAACGCGCCTGCGGCAGGC
TCGGCGCCGTCCGCACGCGCCTCCGCATCGAGCCAGCCGATCGCGCCCGTATAGAGTCCGCGCGGCGTCG
TCTCGAGCGCATCGATCAGTTGCATCGTCCTGTGCTTCGGCGCGCCCGTGATCGAGCCGCACGGAAAGAG
CGCGCGCAGCACGTCGGCGAACGTCGCGCCTTCGACGATGCCCGCCTCGACCGTCGACGTCATCTGCCAC
ACCGACGCATACGGCTCGACCGAGAACAACGCCGGCACCGTCACCGATCCGGTGCGCGCGATGCGCGCGA
GATCGTTGCGCAGCAGATCGACGATCATCACGTTCTCGGCGCGATTCTTCGCATCGTTCGCGAGAAAGCG
CGCGGCGGCCGCATCCTCGCGCGGATCGTCCGAGCGAGGCGCGGTGCCTTTCATCGGCCGCGCGCGCAGC
AACGCGCCCGTCTTCTCGACGAACAGCTCGGGCGAGCACGATACGATCCACGCGCCGCCCGGCAGCGCGA
CGAGCGCGCCGTAGCGCACCGGCTGGCGCGCCCGCAGGCGGCGATACAGCGCGAGCGGCGCGCCGAACGC
ATCGAAATGCAGCCGGTACGTGTAGTTGATCTGATACGAATCGCCCGCGCGCAGCGCATCGTGCACGGCG
GCGATCGCCGCGTCGAACGCGTCGCGCGCGACGCTCTTCGTCACGTGCGCGACGCCCGCCGCCGACGGCT
CGGCCGAGCCGCCGTCGCGCGACGCGAGCCACGCGTCGGCCTCCTCGCGCGAGAGCATCCTGCATTCGGC
GAACAGCAGGAACCGCAACGCGCCGCCGCCGCGCTTGCCGAGCTGCAGGTCGCGCCCGAACTCGTAGTCG
CCGAGCACGACGGCGTGCAGCCCGCGCCGCGCGTCGTCGGCGACGGCCGCGCACACCGCGTCGAGGCCGG
CCGGATCGGCGCAGGCCCGCTCGTGCGAGAAGCCCGAATACAAACGACTCGAGCGCGCCGCCGCGGTCGA
GTCGCAATCGTCGAAGAGCGCGAAAACCGCGCCCGCTTCGTCAGTCATCCTGCCTCTCA
Protein Sequence 
>gi|53720434|ref|YP_109420.1| hypothetical protein BPSL2825 [Burkholderia pseudomallei K96243]
MRGRMTDEAGAVFALFDDCDSTAAARSSRLYSGFSHERACADPAGLDAVCAAVADDARRGLHAVVLGDYE
FGRDLQLGKRGGGALRFLLFAECRMLSREEADAWLASRDGGSAEPSAAGVAHVTKSVARDAFDAAIAAVH
DALRAGDSYQINYTYRLHFDAFGAPLALYRRLRARQPVRYGALVALPGGAWIVSCSPELFVEKTGALLRA
RPMKGTAPRSDDPREDAAAARFLANDAKNRAENVMIVDLLRNDLARIARTGSVTVPALFSVEPYASVWQM
TSTVEAGIVEGATFADVLRALFPCGSITGAPKHRTMQLIDALETTPRGLYTGAIGWLDAEARADGAEPAA
GAFAPERAASSSPGTASDGACAGETASKQASKRAGATSPAGACGDFCLSVAIRTLTLDAPSAGGERRGTM
GVGAGIVLDSVAADEYAECELKARFLTDAEPGFQLFETMLATRDAGVRHLDRHVARLRASADALGFAFDE
AAARQRIGARCVQLGDGEHRLRVALAKDGVLDIVAAPLAPLAGAAVAVLLAPEHGFAPMRSGDFLLAHKT
TRRADYDRAWKAAQACGAFDMLFFNERGELTEGGRTSVFVKLAGRWFTPPLSSGVLPGVMRGALLDDPAW
QASERVMTLDDVLRADALMLTNALRGAMPAQLVRAAGAAAPR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: BPSL2825 mutant is attenuated in mice (Pilatz et al., 2006).
COG COG0147EH, under E: Amino acid transport and metabolism; H: Coenzyme transport and metabolism
References
Pilatz et al., 2006: Pilatz S, Breitbach K, Hein N, Fehlhaber B, Schulze J, Brenneke B, Eberl L, Steinmetz I. Identification of Burkholderia pseudomallei genes required for the intracellular life cycle and in vivo virulence. Infection and immunity. 2006; 74(6); 3576-3586. [PubMed: 16714590].