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wcbD

Victor ID 2011
Gene Name wcbD
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3094162
NCBI Protein GI 53720415
Locus Tag BPSL2806
Genbank Accession BX571965
Protein Accession YP_109401
Other Database IDs UniProtKB-ID: Q7BMG7_BURPS
UniRef100: UniRef100_Q9AI47
UniRef90: UniRef90_Q9AI47
UniRef50: UniRef50_C4KUC9
UniParc: UPI00000BEFAA
EMBL: AF228583
EMBL: BX571965
EMBL-CDS: AAK49797.1
EMBL-CDS: CAH36815.1
RefSeq_NT: NC_006350.1
GenomeReviews: BX571965_GR
KEGG: bps:BPSL2806
HOGENOM: HBG655419
OMA: PRRIYNI
ProtClustDB: CLSK834230
BioCyc: BPSE272560:BPSL2806-MONOMER
Taxonomy ID 272560
Chromosome No 1
Gene Starting Position 3353700
Gene Ending Position 3354848
Gene Strand (Orientation) -
Protein Name putative capsule polysaccharide export ABC transporter transmembrane protein
Protein pI 8.76
Protein Weight 39708.31
Protein Length 382
Protein Note Also known as bexCSimilar to Haemophilus influenzae capsule polysaccharide export inner-membrane protein BexC SWALL:BEXC_HAEIN (SWALL:P22930) (377 aa) fasta scores: E(): 7.1e-55, 41.99% id in 381 aa. Identical to Burkholderia mallei putative capsule polysaccharide export inner-membrane protein WcbD SWALL:Q9AI47 (EMBL: AF285636) (382 aa) fasta scores: E(): 3.7e-135, 100% id in 382 aa
DNA Sequence 
>gi|53717639:3353700-3354848 Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence
GTCATTCCTGATGTTCACGAATACCCGCTACCAGCATGCTCAACACGCCCCAGGCCGCGAGCCCCAAAAT
GAAACAGGCAAATATGTTCCGGACACGCTTGGGTTCCATCGCCACGTCCGGTTCGTTCGGTTCCGCAACC
CGTTCCAGATAGATTTGTTTTCTTTCCGCATCTGCCCTGGCTTGCTCCAACGATGTCAGCGCAGAGGCAA
GAAGCTTCTCCCCGAACGATTGCTCCAAAGCCAGGCGCTGGTACTCGACCGAACGGTCCGACAACGAATT
CTTCTCTCCCGCCACGCCCCCTTTCTCGCTCGCAATCGACGCTTCCAACGCGCCGATAGACGCGGCCAGA
CTCGGGATCTGCGGATTCTGCGGGCTGAGCATGCGCAATTGCGATAGCTGCGCCTGCTTGGCAATGAGCT
CGCCCCGCAACTTCGCTACCAGTTCCAGTTGGATATTGGACTGCCGATCCGGATCGAACAGACTCGCCTT
GCTTCGGAATTTCGACAACGCCGTCGACGCAGCCTTTACCTTCGCTTCCGCTCCCGCCACCTCCGCAAGG
GCGTAACGGAGCGAATCCTGACGTGAGCGATCGTTGAGTTCATTGACTCGCTTCTCCGCCATCTCGAGCA
AATACTTGTTGATCAGGTATGCGTCTTTCGACGTATAGGCCTGAACGCGTAGCGTAGTGACCGCAGTTGC
AGTCCCTACGTCGACGGCAACATGGTTTTTGAAATAGCGGTAGAAATACTCGAAGCCATCGCGCCCGATC
ACGCCCGGGAATCGACTGAAGATATCAGCATAGCGACCGCCAAATGCATCTCTGAGCGGCATTTTCTGCT
CGAGAACGACGAGTGCGTCTCTCGACTTTATGTAATCTTGAACGACACTGGTGTCGTCACTGGTCTTTGA
TAGGGAGACGCCCTGAAGCAATGCCCCCAAACCCGGTTCGCTCGTTCGCTTGGGCGTACGCAGGATAAAC
TGCGATTCCGAGATGTAGACATCCGACGCAATCAGCCCGTAGTAGAGGGTAGCGATTGCAGTCGGCAGCA
CCACCGTCACCAGAAACAACGGGGTCAGCCTCAGCCGCCCGATCGTCCATACCCGCCAGAACCATGACGA
CTCCTGCGCCGGAGCATCGAAGCTCTCCA
Protein Sequence 
>gi|53720415|ref|YP_109401.1| putative capsule polysaccharide export ABC transporter transmembrane protein [Burkholderia pseudomallei K96243]
MESFDAPAQESSWFWRVWTIGRLRLTPLFLVTVVLPTAIATLYYGLIASDVYISESQFILRTPKRTSEPG
LGALLQGVSLSKTSDDTSVVQDYIKSRDALVVLEQKMPLRDAFGGRYADIFSRFPGVIGRDGFEYFYRYF
KNHVAVDVGTATAVTTLRVQAYTSKDAYLINKYLLEMAEKRVNELNDRSRQDSLRYALAEVAGAEAKVKA
ASTALSKFRSKASLFDPDRQSNIQLELVAKLRGELIAKQAQLSQLRMLSPQNPQIPSLAASIGALEASIA
SEKGGVAGEKNSLSDRSVEYQRLALEQSFGEKLLASALTSLEQARADAERKQIYLERVAEPNEPDVAMEP
KRVRNIFACFILGLAAWGVLSMLVAGIREHQE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: wcbD mutant is attenuated in mice (Cuccui et al., 2007).
COG COG3524M, under M: Cell wall/membrane/envelope biogenesis
References
Cuccui et al., 2007: Cuccui J, Easton A, Chu KK, Bancroft GJ, Oyston PC, Titball RW, Wren BW. Development of signature-tagged mutagenesis in Burkholderia pseudomallei to identify genes important in survival and pathogenesis. Infection and immunity. 2007; 75(3); 1186-1195. [PubMed: 17189432].