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BPSL1876

Victor ID 2015
Gene Name BPSL1876
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3094734
NCBI Protein GI 53719489
Locus Tag BPSL1876
Genbank Accession BX571965
Protein Accession YP_108475
Other Database IDs UniProtKB-ID: Q63TU1_BURPS
UniRef100: UniRef100_Q62K32
UniRef90: UniRef90_Q3JST8
UniRef50: UniRef50_Q3JST8
UniParc: UPI000043B17E
EMBL: BX571965
EMBL-CDS: CAH35875.1
RefSeq_NT: NC_006350.1
GenomeReviews: BX571965_GR
KEGG: bps:BPSL1876
HOGENOM: HBG370131
OMA: LFLYSAT
ProtClustDB: CLSK708868
BioCyc: BPSE272560:BPSL1876-MONOMER
Taxonomy ID 272560
Chromosome No 1
Gene Starting Position 2232807
Gene Ending Position 2234327
Gene Strand (Orientation) +
Protein Name putative phospholipase
Protein pI 6.51
Protein Weight 52548.35
Protein Length 506
Protein Note Similar to Arabidopsis thaliana putative phospholipase t12j13.18 or t21p5.4 SWALL:Q9S816 (EMBL: AC009327) (521 aa) fasta scores: E(): 3.4e-32, 30.87% id in 502 aa, and to Sulfolobus solfataricus acid phosphatase, putative sso2789 SWALL:Q97V43 (EMBL: AE006873) (511 aa) fasta scores: E(): 5.1e-08, 25.63% id in 476 aa
DNA Sequence 
>gi|53717639:2232807-2234327 Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence
CATGCACGCCGGAGGCCCCCAACGGAGTCCGCTCGTGGCGAATTCACTCTCCAGGATCGAGCACATCGTC
CATCTGATGCTCGAAAACCGCTCGTTCGATCAGATGCTCGGCTTTCTCTACACCGACGACGGCAATCGCT
CTCCCACCGGGCAGCCGTTCGACGGCCTCACCGGCAACGAATCGAATCCGGACGACCTCGGCCGCCCGGT
CGGCGTCTACCGGATCCGCGCCACCGATCCGCATCCGTATCTGATGCCCGGCGCCGATCCCGGCGAAGGC
TTTCAGAACACCAACTATCAACTGTTCTGCGACGACCACCCCGCCCCCGGCGCCGTGCCGACCAATCAGG
GCTTCGTCGTCAACTTCAAGTCGGCGATCGCGACCGATCAGTCGCGGCACGACAAGGACGCGCTGCCCGG
CACGACGCCCGAGCAGATCATGGGCATGTACACGCCGGAGCTGCTGCCCGTGCTGTCCGGGCTCGCGAAG
GGCTATGCGGTGTGCGACCGCTGGTTCGCGTCTGCGCCGACGATGACGATGCCCAACCGCGCGTTCGCGC
TCGCCGCCACGTCGCAGGGCCACCTCGACGATCACGTGAAGATCTTCACTTGCCCGAGCATCTTCGGGCG
GTTGTCGGACCAGGGCGTCGACTGGGCGATCTTCGGCTACAACCGCGATCCGCTCACGCGCCACGACTTC
CCCGACACGCAGAACGCCGACGACAGCCACTTCGGCCACTTTCGCGATTTCCAGGCGCGCGCGGCGAGCG
GCACGCTGCCCGCGTTCACGTTCCTCGAACCGAGCTGGGATGCGAGCGGCAACAGCCAGCATCCGAACTA
CGACGTCGCCGCGGGCGAGCAACTGATTCACGACGTCTACTACGCGCTGCGCAACGGCCCCGGCTGGAAT
AGCACGCTCTTCATCGTCACGTACGACGAGCACGGCGGCAACTACGATCACGTCGCGCCGCCGTCCGGCG
CGACGCCGCCCGGCGACGGCACCGTCGGCGAATTCGGCTTCGACTTCACGCGCTTCGGCGTGCGCGTGCC
CGCGGTGCTCGTCTCGCCGCTGATCGCGGCGGGCACCGTGTTTCGCAGCGCGGCGGGCACGATCGATCAC
ACGTCGGTGCTGAAGACGATCGGCGAGCGCTTCGGGACGGCGCCGCTGACGGCGCGCGACCGCGCCGCGC
CGTCGCTCGGCGACGCGCTCACGCTCGCGAGCCCGCGCGCCGCGAGCGACGATCCGCTCGCCGGCGTGAC
CGTACCCGTGTCGCGCGTGTCCCATCCGAACGCGGCGATGCCGTCGAAGCTCGACAAGCTCCAGGCGGCC
CGCATCGCGGCACTGCCGCTGCGCAACGAGAAGGGTTATTACGAGGAGGCCGACACGCCGCTCGCATCGA
GCGCCGAACTGTCGAACTTCATTCGGGACCGCGGCGCCGCGTGGAGCCAGCATCGCCAGCGGCAACAGCA
ACGGCGGCAGCAACAGCAACGACAACAGCCGCGGAGCAAGCCGCGCCGCTG
Protein Sequence 
>gi|53719489|ref|YP_108475.1| putative phospholipase [Burkholderia pseudomallei K96243]
MHAGGPQRSPLVANSLSRIEHIVHLMLENRSFDQMLGFLYTDDGNRSPTGQPFDGLTGNESNPDDLGRPV
GVYRIRATDPHPYLMPGADPGEGFQNTNYQLFCDDHPAPGAVPTNQGFVVNFKSAIATDQSRHDKDALPG
TTPEQIMGMYTPELLPVLSGLAKGYAVCDRWFASAPTMTMPNRAFALAATSQGHLDDHVKIFTCPSIFGR
LSDQGVDWAIFGYNRDPLTRHDFPDTQNADDSHFGHFRDFQARAASGTLPAFTFLEPSWDASGNSQHPNY
DVAAGEQLIHDVYYALRNGPGWNSTLFIVTYDEHGGNYDHVAPPSGATPPGDGTVGEFGFDFTRFGVRVP
AVLVSPLIAAGTVFRSAAGTIDHTSVLKTIGERFGTAPLTARDRAAPSLGDALTLASPRAASDDPLAGVT
VPVSRVSHPNAAMPSKLDKLQAARIAALPLRNEKGYYEEADTPLASSAELSNFIRDRGAAWSQHRQRQQQ
RRQQQQRQQPRSKPRR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: BPSL1876 mutant is attenuated in mice (Tuanyok et al., 2006).
COG COG3511M, under M: Cell wall/membrane/envelope biogenesis
References
Tuanyok et al., 2006: Tuanyok A, Tom M, Dunbar J, Woods DE. Genome-wide expression analysis of Burkholderia pseudomallei infection in a hamster model of acute melioidosis. Infection and immunity. 2006; 74(10); 5465-5476. [PubMed: 16988221].