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wcbN

Victor ID 1995
Gene Name wcbN
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3091825
NCBI Protein GI 53720402
Locus Tag BPSL2793
Genbank Accession BX571965
Protein Accession YP_109388
Other Database IDs UniProtKB-ID: Q63R80_BURPS
UniRef100: UniRef100_Q9AI34
UniRef90: UniRef90_Q9AI34
UniRef50: UniRef50_Q9AI34
UniParc: UPI00000BBEA8
EMBL: BX571965
EMBL-CDS: CAH36802.1
RefSeq_NT: NC_006350.1
GenomeReviews: BX571965_GR
KEGG: bps:BPSL2793
HOGENOM: HBG613347
OMA: VVLDSIA
ProtClustDB: CLSK710582
BioCyc: BPSE272560:BPSL2793-MONOMER
Taxonomy ID 272560
Chromosome No 1
Gene Starting Position 3340907
Gene Ending Position 3341476
Gene Strand (Orientation) -
Protein Name putative D-glycero-d-manno-heptose 1,7-bisphosphate phosphatase
Protein pI 4.71
Protein Weight 19038.92
Protein Length 189
Protein Note Also known as gmhCSimilar to Aneurinibacillus thermoaerophilus D-glycero-d-manno-heptose 1,7-bisphosphate phosphatase GmhC SWALL:Q9AGY5 (EMBL: AF324836) (179 aa) fasta scores: E(): 3.6e-35, 60% id in 155 aa. Identical to Burkholderia mallei WcbN protein SWALL:Q9AI34 (EMBL: AF285636) (189 aa) fasta scores: E(): 9.5e-78, 100% id in 189 aa
DNA Sequence 
>gi|53717639:3340907-3341476 Burkholderia pseudomallei K96243 chromosome chromosome 1, complete sequence
CCTAGAACGATCCGGCATCCGGTCCGGGGCCCGTCAGGAACGGAATGACGTCACGCGGATTGCGGACGAC
GGCGCTCGCCGCCGTCGCCACACGCGATGCGTCCCGGTCGCATATGAGGAGAGTCGTCCCGACACCCGCC
GTCGACCCGGCTTGAATATCGGACTCCTTATCCCCGACAAGTAACGACGCCCCCAGATCGAGATCGAAGT
CATGCTGCGCCGCGAGGATCATCCCCGGATTCGGCTTCCTGAACCGGGACTCGACCTTATATCGGCCAAT
GCCGTGCTCGGGATGTGTCGGACAAAAGTACACGCCGTCGATCGGCGCGCCTTCGGTCGCGAAGACCCCT
TTCATCCAGTCGGACAGGCGAAAAAAATCGTCTTCCGAATAGTAGCCGCGCCCGATCCCCGCCTGGTTCG
TCACCACGATGCTCAGATATCCCAACGCCTTGGCGGCTCCGGCAAGCTCGAAAATTCCGTCCAGAAAGAC
AAATTTCTCGATCTCGAAAACATAGCCGTCGTCGCGATTGATCACCCCATCGCGATCCAGGAACAACGCG
CGATTCTTCA
Protein Sequence 
>gi|53720402|ref|YP_109388.1| putative D-glycero-d-manno-heptose 1,7-bisphosphate phosphatase [Burkholderia pseudomallei K96243]
MKNRALFLDRDGVINRDDGYVFEIEKFVFLDGIFELAGAAKALGYLSIVVTNQAGIGRGYYSEDDFFRLS
DWMKGVFATEGAPIDGVYFCPTHPEHGIGRYKVESRFRKPNPGMILAAQHDFDLDLGASLLVGDKESDIQ
AGSTAGVGTTLLICDRDASRVATAASAVVRNPRDVIPFLTGPGPDAGSF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: wcbN mutant is attenuated in mice (Cuccui et al., 2007).
COG COG0241E, under E: Amino acid transport and metabolism
References
Cuccui et al., 2007: Cuccui J, Easton A, Chu KK, Bancroft GJ, Oyston PC, Titball RW, Wren BW. Development of signature-tagged mutagenesis in Burkholderia pseudomallei to identify genes important in survival and pathogenesis. Infection and immunity. 2007; 75(3); 1186-1195. [PubMed: 17189432].