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bopE

Victor ID 1986
Gene Name bopE
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3096393
NCBI Protein GI 53722546
Locus Tag BPSS1525
Genbank Accession BX571966
Protein Accession YP_111531
Other Database IDs UniProtKB-ID: BOPE_BURPS
UniRef100: UniRef100_Q3JL30
UniRef90: UniRef90_A3MCH6
UniRef50: UniRef50_Q3JL30
UniParc: UPI000043BD17
EMBL: BX571966
EMBL-CDS: CAH38998.1
RefSeq_NT: NC_006351.1
PDB: 2JOK
PDB: 2JOL
GenomeReviews: BX571966_GR
KEGG: bps:BPSS1525
HOGENOM: HBG042551
OMA: VKRSEAR
ProtClustDB: CLSK894591
BioCyc: BPSE272560:BPSS1525-MONOMER
Taxonomy ID 272560
Chromosome No 2
Gene Starting Position 2078019
Gene Ending Position 2078804
Gene Strand (Orientation) +
Protein Name G-nucleotide exchange factor
Protein pI 9.89
Protein Weight 27216.55
Protein Length 261
Protein Note Similar to Salmonella enterica subsp. VII G-nucleotide exchange factor SopE SWALL:Q8VSR1 (EMBL: AF378113) (240 aa) fasta scores: E(): 8.6e-08, 28.77% id in 212 aa, and to Salmonella gallinarum G-nucleotide exchange factor SopE SWALL:Q8VSQ6 (EMBL: AF380340) (240 aa) fasta scores: E(): 1.5e-07, 24.56% id in 228 aa
DNA Sequence 
>gi|53721039:2078019-2078804 Burkholderia pseudomallei K96243 chromosome 2, complete sequence
CATGACTTACAACCCGAGAATCGGCGGATTCACGCACGTCAAGCAGGCGTCGTTCGACGTTCACGTCAAG
CGCGGCGAAGCGCAGCCGCGCACGTCGTTCGCACAACAGATCAAGCGCATCTTCAGCAAGATCGGCGAAA
CGCTCGGGCAACTGTTCCGCCACCGCGCGCCGGACAGCGCGCCCGGCCGGGTCAGGCTGCAGGGCGTGCG
CTACGTCGGCAGCTATCGGCCCACGGGCGACGCGAAACAGGCGATCCGGCATTTCGTCGACGAAGCGGTC
AAGCAGGTCGCCCACGCGCGTACCCCGGAGATCCGGCAGGATGCCGAATTCGGCCGGCAAGTCTACGAAG
CGACGCTCTGCGCGATCTTCAGCGAAGCGAAGGACCGGTTCTGCATGGACCCGGCCACGCGCGCGGGCAA
CGTGCGGCCGGCGTTCATCGAGGCGCTCGGCGACGCGGCGCGTGCGACGGGGCTGCCCGGCGCCGACAAG
CAAGGCGTGTTCACGCCGAGCGGCGCCGGCACGAATCCGCTCTACACCGAGATCCGGCTGCGCGCCGATA
CGCTGATGGGCGCCGAGCTGGCCGCGCGCCCGGAGTATCGCGAGCTTCAGCCGTATGCGCGGCAGCAGGC
GATCGATCTCGTCGCGAACGCGTTGCCGGCCGAGCGTTCGAACACGCTCGTCGAGTTCCGGCAGACGGTG
CAGACGCTCGAAGCCACATACCGCCGCGCGGCACAAGACGCGTCGCGCGACGAGAAGGGCGCGACGAACG
CGGCGGACGGCGCGTG
Protein Sequence 
>gi|53722546|ref|YP_111531.1| G-nucleotide exchange factor [Burkholderia pseudomallei K96243]
MTYNPRIGGFTHVKQASFDVHVKRGEAQPRTSFAQQIKRIFSKIGETLGQLFRHRAPDSAPGRVRLQGVR
YVGSYRPTGDAKQAIRHFVDEAVKQVAHARTPEIRQDAEFGRQVYEATLCAIFSEAKDRFCMDPATRAGN
VRPAFIEALGDAARATGLPGADKQGVFTPSGAGTNPLYTEIRLRADTLMGAELAARPEYRELQPYARQQA
IDLVANALPAERSNTLVEFRQTVQTLEATYRRAAQDASRDEKGATNAADGA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: bopE mutant is attenuated in mice (Stevens et al., 2004).
References
Stevens et al., 2004: Stevens MP, Haque A, Atkins T, Hill J, Wood MW, Easton A, Nelson M, Underwood-Fowler C, Titball RW, Bancroft GJ, Galyov EE. Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis. Microbiology (Reading, England). 2004; 150(Pt 8); 2669-2676. [PubMed: 15289563].