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BPSS0067

Victor ID 1988
Gene Name BPSS0067
Sequence Strain (Species/Organism) Burkholderia pseudomallei K96243
NCBI Gene ID 3096819
NCBI Protein GI 53721107
Locus Tag BPSS0067
Genbank Accession BX571966
Protein Accession YP_110092
Other Database IDs UniProtKB-ID: Q63P77_BURPS
UniRef100: UniRef100_B7CTA0
UniRef90: UniRef90_Q3JI69
UniRef50: UniRef50_Q3JI69
UniParc: UPI000043B797
EMBL: BX571966
EMBL-CDS: CAH37511.1
RefSeq_NT: NC_006351.1
GenomeReviews: BX571966_GR
KEGG: bps:BPSS0067
NMPDR: fig|272560.3.peg.894
HOGENOM: HBG565180
OMA: FEVTSES
ProtClustDB: CLSK708841
BioCyc: BPSE272560:BPSS0067-MONOMER
Taxonomy ID 272560
Chromosome No 2
Gene Starting Position 76173
Gene Ending Position 78368
Gene Strand (Orientation) +
Protein Name phospholipase C precursor
Protein pI 9.04
Protein Weight 75579.39
Protein Length 731
Protein Note Similar to Pseudomonas aeruginosa non-hemolytic phospholipase C precursor PlcN or pa3319 SWALL:PHLN_PSEAE (SWALL:P15713) (692 aa) fasta scores: E(): 6e-54, 53.29% id in 728 aa, and to Burkholderia pseudomallei non-hemolytic phospholipase C precursor PlcN SWALL:PHLN_BURPS (SWALL:Q9RGS8) (700 aa) fasta scores: E(): 4e-39, 45.43% id in 744 aa
DNA Sequence 
>gi|53721039:76173-78368 Burkholderia pseudomallei K96243 chromosome 2, complete sequence
CATGAACGCTCGTCGCAGATTTCTGCAAGGCACCGCAACCACCGGCATCGCGGCCGCCACGTTGGCCGCG
TTTCCGCTCAGCATTCGCCGCGCACTCGCGATTCCCGCCAACAACCGCACCGGAACCATCCGGGATGTCG
AGCACATCGTCATCCTGATGCAGGAAAACCGCTCGTTCGACAACTACTTCGGCACGCTGCGCGGCGTGCG
CGGCTTTGGCGACCGCTTCGGCATTCCGCTGCCGAACGCGCTGACGGTCTGGCAGCAGCGCAACGCGACG
GGCGCGCTGGTGCTGCCCTATCACCTGGACGGCAGCAAGGGCAACGCACAGCGCGTCAGCGGCACGCCGC
ACTCGTGGGACGACGGGCAGAACGCGTGGGACGGCGGGCGCATGTATCAGTGGCCGCGCTACAAGAACAC
GGCGTCGATGGGCTACTTCCGGGAGAGCGAGCTGCCGTTCCAGTTCGCGCTCGCGAACGCGTTCACGATC
TGCGATGCGTACCACTGCTCGATGCACGCGGGCACCAACTCCAACCGGATGTTCATGTGGACCGGCACCA
ACGGCCCGACCGGCGCGGGCGTGGCCTCGGTGGTGAACGAATGGGACGACATCGGTCCCTCCACGTTCGG
CTATGAGTGGAAGACCTATCCCGAGCGCTTGCAGGAAGCCGGCGTGAGCTGGAAGGTCTACCAGAACATG
CCGGACAACTTCACCGACAACGCGCTTGCCGGCTTCAGGCAGTACCGCCGCGCGAACGAGGCGTCGGGCA
AGCCGGTGAGCAACAGCGACAAGGTGGTTTCGCCCGCATACGATCCGGCGAGCGACGACGTTCGCAACCC
GCTGTACAAGGGCATCGCCAACACGATGCCCGACGGCGGCTTCCTCGGCGCCTTCAAGGAAGACATCCGT
GCGGGCAAGCTGCCGCAGGTGTCGTGGGTGGTGGCGCCGGCCGCGTATTCCGAGCATCCGGGGCCGTCGA
GCCCGGTGCAGGGCGCGTGGTACATCCAGGAGGTGCTCGATGCGCTCACCGCGACGCCGGACGTCTGGAG
CAAGACCGTGCTGCTCGTGAATTTCGACGAGAACGACGGCTACTTCGACCACGTGCCTTCGCCGTCGGCG
CCGTCGCTGAATCCGGACGGCTCGCCGGCCGGCAAGACCACGCTGCCCGAGGCCGACATCGCGTTCGAGC
GCTTCACCCATCCGAAGCCGCCGGGCACCAAGAGCCAGCCGCAGCCCGACGCCCGCGTATATGGCCCCGG
CGTGCGCGTGCCGATGTACGTGATCTCGCCGTGGAGCCGCGGCGGCTGGGTCAACTCGCAGGTGTTCGAT
CACACGTCGACGCTGCGTTTCATCGAGGCGCGCTTCGGTGTGCGCGAGCCCAATATCTCCGCGTTCCGCC
GCTCGGTATGCGGCGATCTGACGAGCGCGTTCAACTTCGTGCGACCGAACAACGAGCCGCTGCCCACGCT
GGCGGGGCGCAAGACCCGGGCTCAGGCCGATGCGCTGCGCGCCGCGCAGCAGCAGATGCCGCAGATCGTG
CCGCCTGCGAACGGCCTATTGCCGCGCCAGGAGACAGGCACGCGGCCGTCGCGCGCGTTGCCGTACGAAC
TGCATGTCAACGCGGTCGCGCGCACGCTCGACGGCACGCTGCGCCTCGTATTCGCCAACACGGGGCAGGC
CGCGGCCGTGTTCCACGTCTACGACAAGCTGAATCTGGGCCGCCTGCCGCGCCGATACATGGTCGAGGCC
GGCAAGCAGCTCGACGACGTCTGGGCCGCGATGACGGACAACGGCGGCAAGTACGACCTGTGGGTGCTCG
GGCCCAACGGCTTGCACCGCCATTTCACCGGCGATATGAACCGCCTGCGCGCGGGCGGCGCGCCCGTGCC
CGAAGTGCGGGTGGAGTACGACCGCCAGCACGGCAACGTGCAATTGCTGTTGCGTAACGAAGGGGCGCGC
GAGTGCGTGTTCACCGTGCGCGCGAAGGCGTACCGCGACGATGGTCCGTGGACCTTCAAGGTCAAGGGCG
GCGCCGAGCGCAAGCATCACTGGAAGCTGGACGGCAGCGGCAATTGGTACGACTTCGTTGTGACCTGCGA
CGCCGACACCGGTTACTCGCGCCGCTTCGCCGGGCGGGTGGAAACCGGCGAGCACTCCGTCAGCGATCCG
GCGATGGGGTTCGGCGATCGGTTCTG
Protein Sequence 
>gi|53721107|ref|YP_110092.1| phospholipase C precursor [Burkholderia pseudomallei K96243]
MNARRRFLQGTATTGIAAATLAAFPLSIRRALAIPANNRTGTIRDVEHIVILMQENRSFDNYFGTLRGVR
GFGDRFGIPLPNALTVWQQRNATGALVLPYHLDGSKGNAQRVSGTPHSWDDGQNAWDGGRMYQWPRYKNT
ASMGYFRESELPFQFALANAFTICDAYHCSMHAGTNSNRMFMWTGTNGPTGAGVASVVNEWDDIGPSTFG
YEWKTYPERLQEAGVSWKVYQNMPDNFTDNALAGFRQYRRANEASGKPVSNSDKVVSPAYDPASDDVRNP
LYKGIANTMPDGGFLGAFKEDIRAGKLPQVSWVVAPAAYSEHPGPSSPVQGAWYIQEVLDALTATPDVWS
KTVLLVNFDENDGYFDHVPSPSAPSLNPDGSPAGKTTLPEADIAFERFTHPKPPGTKSQPQPDARVYGPG
VRVPMYVISPWSRGGWVNSQVFDHTSTLRFIEARFGVREPNISAFRRSVCGDLTSAFNFVRPNNEPLPTL
AGRKTRAQADALRAAQQQMPQIVPPANGLLPRQETGTRPSRALPYELHVNAVARTLDGTLRLVFANTGQA
AAVFHVYDKLNLGRLPRRYMVEAGKQLDDVWAAMTDNGGKYDLWVLGPNGLHRHFTGDMNRLRAGGAPVP
EVRVEYDRQHGNVQLLLRNEGARECVFTVRAKAYRDDGPWTFKVKGGAERKHHWKLDGSGNWYDFVVTCD
ADTGYSRRFAGRVETGEHSVSDPAMGFGDRF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: BPSS0067 mutant is attenuated in mice (Tuanyok et al., 2006).
COG COG3511M, under M: Cell wall/membrane/envelope biogenesis
References
Tuanyok et al., 2006: Tuanyok A, Tom M, Dunbar J, Woods DE. Genome-wide expression analysis of Burkholderia pseudomallei infection in a hamster model of acute melioidosis. Infection and immunity. 2006; 74(10); 5465-5476. [PubMed: 16988221].