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pabB from Burkholderia pseudomallei 1106a

Victor ID 1963
Gene Name pabB from Burkholderia pseudomallei 1106a
Sequence Strain (Species/Organism) Burkholderia pseudomallei 1106a
NCBI Gene ID 4902449
NCBI Protein GI 126454445
Locus Tag BURPS1106A_3308
Protein Accession YP_001067545.1
Other Database IDs UniProtKB-ID: A3NYX4_BURP0
UniRef100: UniRef100_A3NYX4
UniRef90: UniRef90_A1V0U9
UniRef50: UniRef50_A1V0U9
UniParc: UPI00005FAF1D
EMBL: CP000572
EMBL-CDS: ABN91627.1
RefSeq_NT: NC_009076.1
GenomeReviews: CP000572_GR
KEGG: bpl:BURPS1106A_3308
TIGR: BURPS1106A_3308
eggNOG: COG0147
HOGENOM: HBG507440
OMA: VNYTYRL
ProtClustDB: CLSK931093
Taxonomy ID 357348
Chromosome No I
Gene Starting Position 3225452
Gene Ending Position 3227461
Gene Strand (Orientation) -
Protein Name para-aminobenzoate synthase, component I
DNA Sequence 
>gi|126451443:3225452-3227461 Burkholderia pseudomallei 1106a chromosome I, complete genome
CCTATCGCGGTGCCGCCGCGCCGGCGGCCCGCACGAGTTGCGCGGGCATCGCGCCGCGCAATGCGTTCGT
CAGCATCAGCGCGTCGGCGCGCAGCACGTCGTCCAGCGTCATTACACGCTCGGACGCCTGCCATGCCGGA
TCGTCGAGCAGCGCGCCGCGCATCACGCCCGGCAACACGCCCGACGACAGCGGCGGCGTGAACCAGCGCC
CGGCCAGCTTCACGAATACGCTCGTGCGCCCGCCTTCGGTCAATTCGCCGCGTTCGTTGAAGAACAGCAT
GTCGAACGCACCGCACGCCTGCGCGGCTTTCCACGCGCGATCGTAATCGGCGCGGCGCGTCGTCTTGTGC
GCGAGCAGGAAGTCGCCCGAGCGCATCGGCGCGAACCCGTGCTCGGGCGCGAGCAACACGGCCACCGCGG
CGCCCGCGAGCGGCGCGAGCGGCGCGGCCACGATGTCGAGCACGCCGTCCTTCGCGAGCGCGACGCGCAA
GCGATGCTCGCCGTCGCCGAGCTGCACGCAGCGCGCGCCGATGCGCTGCCTGGCCGCCGCTTCGTCGAAC
GCGAAGCCGAGCGCGTCGGCACTCGCGCGCAGCCGCGCGACATGGCGGTCGAGATGGCGCACGCCGGCGT
CACGCGTGGCGAGCATCGTCTCGAACAACTGGAAGCCGGGCTCGGCGTCGGTCAGGAAACGCGCCTTCAA
TTCGCACTCCGCGTATTCGTCGGCGGCAACGCTGTCGAGCACGATGCCCGCGCCGACGCCCATCGTGCCG
CGCCGCTCGCCGCCGGCCGACGGCGCGTCGAGCGTCAGCGTGCGGATCGCGACCGACAGGCAGAAATCGC
CGCACGCGCCGGCCGGGCTTGTCGCGCCGGCACGCTTCGACGCCTGCTTCGACGCGATTTCGCCCGCGCA
CGCACCATCCGACGCCGTGCCTGCGGCCGGGCTCGCCGCACGCGCCGGCGCGAACGCGCCGGCGGCAGGC
TCGGCGCCGTCCGCACGCGCCTCCTCCGCATCGAGCCAGCCGATCGCGCCCGTATAGAGCCCGCGCGGCG
TCGTCTCGAGCGCATCGATCAGTTGCATCGTCCTGTGCTTCGGCGCGCCCGTGATCGAGCCGCACGGAAA
GAGCGCGCGCAGCACGTCGGCGAACGTCGCGCCTTCGACGATGCCCGCCTCGACCGTCGACGTCATCTGC
CACACCGACGCATACGGCTCGACCGAGAACAACGCCGGCACCGTCACCGATCCGGTGCGCGCGATGCGCG
CGAGATCGTTGCGCAGCAGATCGACGATCATCACGTTCTCGGCGCGATTCTTCGCATCGTTCGCGAGAAA
GCGCGCGGCGGCCGCATCCTCGCGCGGATCGTCCGAGCGAGGCGCGGTGCCTTTCATCGGCCGCGCGCGC
AGCAACGCGCCCGTCTTCTCGACGAACAGCTCGGGCGAGCACGACACGATCCACGCGCCGCCCGGCAGCG
CGACGAGCGCGCCGTAGCGCACCGGCTGGCGCGCCCGCAGGCGGCGATACAGCGCGAGCGGCGCGCCGAA
CGCATCGAAATGCAGCCGGTACGTGTAGTTGATCTGATACGAATCGCCCGCGCGCAGCGCATCGTGCACG
GCGGCGATCGCCGCGTCGAACGCGTCGCGCGCGACGCTCTTCGTCACGTGCGCGACGCCCGCCGCCGACG
GCTCGGCCGAGCCGCCGTCGCGCGACGCGAGCCACGCGTCGGCCTCCTCGCGCGAGAGCATCCTGCATTC
GGCGAACAGCAGGAACCGCAACGCGCCGCCGCCGCGCTTGCCGAGCTGCAGGTCGCGCCCGAACTCGTAG
TCGCCGAGCACGACGGCGTGCAGCCCGCGCCGCGCGTCGTCGGCGACGGCCGCGCACACCGCGTCGAGGC
CGGCCGGATCGGCGCAGGCCCGCTCGTGCGAGAAGCCCGAATACAAACGACTCGAGCGCGCCGCCGCGGT
CGAGTCGCAATCGTCGAAGAGCGCGAAAACCGCGCCCGCTTCGTCAGTCA
Protein Sequence 
>gi|126454445|ref|YP_001067545.1| para-aminobenzoate synthase, component I [Burkholderia pseudomallei 1106a] MTDEAGAVFALFDDCDSTAAARSSRLYSGFSHERACADPAGLDAVCAAVADDARRGLHAVVLGDYEFGRDLQLGKRGGGALRFLLFAECRMLSREEADAWLASRDGGSAEPSAAGVAHVTKSVARDAFDAAIAAVHDALRAGDSYQINYTYRLHFDAFGAPLALYRRLRARQPVRYGALVALPGGAWIVSCSPELFVEKTGALLRARPMKGTAPRSDDPREDAAAARFLANDAKNRAENVMIVDLLRNDLARIARTGSVTVPALFSVEPYASVWQMTSTVEAGIVEGATFADVLRALFPCGSITGAPKHRTMQLIDALETTPRGLYTGAIGWLDAEEARADGAEPAAGAFAPARAASPAAGTASDGACAGEIASKQASKRAGATSPAGACGDFCLSVAIRTLTLDAPSAGGERRGTMGVGAGIVLDSVAADEYAECELKARFLTDAEPGFQLFETMLATRDAGVRHLDRHVARLRASADALGFAFDEAAARQRIGARCVQLGDGEHRLRVALAKDGVLDIVAAPLAPLAGAAVAVLLAPEHGFAPMRSGDFLLAHKTTRRADYDRAWKAAQACGAFDMLFFNERGELTEGGRTSVFVKLAGRWFTPPLSSGVLPGVMRGALLDDPAWQASERVMTLDDVLRADALMLTNALRGAMPAQLVRAAGAAAPR
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: pabB mutant is attenuated in mice (Breitbach et al., 2008).
COG COG0147EH, under E: Amino acid transport and metabolism; H: Coenzyme transport and metabolism
References
Breitbach et al., 2008: Breitbach K, Köhler J, Steinmetz I. Induction of protective immunity against Burkholderia pseudomallei using attenuated mutants with defects in the intracellular life cycle. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2008; 102 Suppl 1; S89-94. [PubMed: 19121696].