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ilvD from Vibrio cholerae O395

Victor ID 2365
Gene Name ilvD from Vibrio cholerae O395
Sequence Strain (Species/Organism) Vibrio cholerae O395
NCBI Gene ID 5137059
NCBI Protein GI 147675499
Locus Tag VC0395_A2491
Protein Accession YP_001218384.1
Taxonomy ID 345073
Chromosome No 2
Gene Starting Position 2642693
Gene Ending Position 2644534
Gene Strand (Orientation) +
Protein Name dihydroxy-acid dehydratase
DNA Sequence 
>gi|147673035:2642693-2644534 Vibrio cholerae O395 chromosome 2, complete sequence
CATGCCTAAGTACCGTTCCGCCACCACCACACACGGACGTAACATGGCGGGTGCGCGCGCATTATGGCGC
GCCACCGGCGTCAAAGAGGAAGATTTTGGTAAACCGATCATTGCGGTGGTCAACTCCTTCACCCAATTTG
TTCCCGGCCATGTGCATTTAAAAGATCTCGGCCAACTGGTCGCACGCGAAATTGAAGCCGCGGGCGGCAT
TGCCAAAGAATTCAACACCATTGCGGTCGATGACGGCATCGCCATGGGCCACGGCGGCATGCTCTACTCG
CTGCCATCGCGTGAACTGATCGCCGATTCCGTCGAATACATGGTCAATGCGCACTGCGCCGATGCCATGG
TGTGTATCTCCAACTGTGACAAAATCACTCCAGGAATGCTGATGGCGGCGATGCGCCTTAATATTCCGGC
GATTTTCGTCTCTGGCGGCCCGATGGAAGCGGGAAAAACCAAGCTTTCTGACCAAATCATCAAGCTCGAC
TTGGTCGATGCCATGATGCAAGGCGCTGACCCCAAAGTATCGGATGCCCAAAGTGAGCAGATTGAACGCT
CGGCCTGTCCTACTTGTGGCTCTTGCTCGGGGATGTTTACCGCCAACTCAATGAACTGCTTGACCGAAGC
GCTGGGTCTCTCTCAGCCGGGTAACGGCTCACTGCTCGCCACGCATGCCGATCGCAAACAGCTGTTTTTG
ACTGCTGGGCAACGGATTGTTGAGCTGACTAAACGTTACTACGAGCAAGATGATGCCTCAGTTTTGCCAC
GCAACATTGCCAACAAAGCAGCGTTTGAAAACGCCATTGCGCTGGATATTGCGATGGGCGGCTCCACCAA
CACGGTGTTACACCTGTTGGCCGCTGCGCAGGAAGGCGAAGTGGAATTTGATATGACCGATATCGATCGC
ATGTCTCGCCAAGTGCCACACTTATGTAAAGTCGCGCCTTCCACTCAGAAATACCATATGGAAGATGTAC
ACCGCGCGGGCGGTGTAATGGGCATTTTGGGTGAGCTACAACGTGCAGGTCTACTCAAGGATCAAACCCG
CACCGTACTAGGCATCTCGCTGCAAGAGCAGCTGGCGCAATACGACGTGAAACAAACCCAAGATCCAGCG
GTACATACTATGTTCCGCGCAGGCCCTGCTGGCATTCGCACCACTCAAGCTTTCTCACAAGATTGCCGTT
GGGATACGCTCGATGACGATCGCCAAGAGGGGTGTATTCGCGATAAAGCGCACGCATTCAGTCAAGATGG
TGGCCTTGCCGTACTCAAAGGCAACTTGGCGATTGACGGCTGCATCGTAAAAACTGCTGGCGTGGATGAA
AGTATCCTCAAATTCCGTGGTCCTGCTGTGGTGTATGAAAGTCAGGAAGACGCGGTCAACGGCATTCTTG
GCGGCCAAGTCAAAGCCGGTGACGTCGTGGTTATTCGTTATGAAGGGCCAAAAGGCGGTCCGGGCATGCA
AGAGATGCTCTACCCAACCACCTACCTCAAATCGATGGGACTGGGTAAACAGTGCGCGCTACTGACCGAT
GGCCGCTTCTCCGGTGGTACGTCCGGCTTGTCGATTGGTCACGCCTCTCCGGAAGCGGCGAATGGCGGTA
CGATCGGCTTGGTACGCAGTGGCGATAGCATCGCGATTGATATTCCCAACCGTTCGATCACGCTCGAAGT
CAGCGAATCTGAGCTAGCAGCTCGCCGCGCTGAACAAGATAAACTCGGCTGGAAACCAGTGGATCGCCAG
CGTACCGTTTCTTTGGCGCTGAAAGCTTATGCCAGCATGGCAACCAGCGCCGACAAAGGTGCAGTGCGCG
ATAAGTCCAAACTTGAGGGCTA
Protein Sequence 
>gi|147675499|ref|YP_001218384.1| dihydroxy-acid dehydratase [Vibrio cholerae O395] MPKYRSATTTHGRNMAGARALWRATGVKEEDFGKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEAAGGIAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPAIFVSGGPMEAGKTKLSDQIIKLDLVDAMMQGADPKVSDAQSEQIERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKQLFLTAGQRIVELTKRYYEQDDASVLPRNIANKAAFENAIALDIAMGGSTNTVLHLLAAAQEGEVEFDMTDIDRMSRQVPHLCKVAPSTQKYHMEDVHRAGGVMGILGELQRAGLLKDQTRTVLGISLQEQLAQYDVKQTQDPAVHTMFRAGPAGIRTTQAFSQDCRWDTLDDDRQEGCIRDKAHAFSQDGGLAVLKGNLAIDGCIVKTAGVDESILKFRGPAVVYESQEDAVNGILGGQVKAGDVVVIRYEGPKGGPGMQEMLYPTTYLKSMGLGKQCALLTDGRFSGGTSGLSIGHASPEAANGGTIGLVRSGDSIAIDIPNRSITLEVSESELAARRAEQDKLGWKPVDRQRTVSLALKAYASMATSADKGAVRDKSKLEG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ilvD mutant is attenuated in mice (Merrell et al., 2002).
COG COG0129EG, under E: Amino acid transport and metabolism; G: Carbohydrate transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].