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VC0965

Victor ID 2428
Gene Name VC0965
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2614218
NCBI Protein GI 15640981
Locus Tag VC0965
Genbank Accession AE003852
Protein Accession NP_230612
Other Database IDs UniProtKB-ID: Q9KTD7_VIBCH
UniRef100: UniRef100_A5F2V8
UniRef90: UniRef90_Q7MMU0
UniRef50: UniRef50_A8GHF7
UniParc: UPI00000C2E38
EMBL: AE003852
EMBL-CDS: AAF94127.1
RefSeq_NT: NC_002505.1
HSSP: P08839
GenomeReviews: AE003852_GR
KEGG: vch:VC0965
TIGR: VC_0965
HOGENOM: HBG456539
OMA: VILVAYD
ProtClustDB: PRK11177
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 1029759
Gene Ending Position 1031480
Gene Strand (Orientation) -
Protein Name phosphoenolpyruvate-protein phosphotransferase
Protein pI 4.44
Protein Weight 59757.67
Protein Length 573
Protein Note Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system
DNA Sequence 
>gi|15640032:1029759-1031480 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
ATTACGCTTTCGCTGCGATGAATTTATCTACGCAAGCTTCAATTTCTGCAGCCGTTGGCAGGGCAAGCGC
CTCTTCAGCCATCGCTTTGATTTCCGCATAATTGGCGTTACGGATCACTTTCTTCACTTTTGGAATCGAG
ATGCCGCTCATTGAGAACTCATCCAGACCCATACCGAGTAGGAGTAGCGTTGCACGCTCGTCACCCGCTA
ATTCACCACACATACCAGTCCATTTGCCTTCTGCGTGAGAAGCATCAATCACCTGCTTGATCACGGTCAG
AACCGCTGGAGAGAGTGGGTTGTAGAGGTGAGAGATCATCTCGTTACCACGGTCTACCGCTAAGGTGTAC
TGAGTTAAATCGTTAGTACCGATAGAGAAGAAAGAGACTTCTTTTGCCAAGTGATGAGCAATCGCTGCTG
CAGCTGGTGTTTCTACCATCACACCGATTTCGATGTTTTCATCGAAAGCATGACCTTCGGTGCGCAGTTC
AGCTTTGTACTCTTCAATCGCATTTTTCAGCTCACGAATTTCTTCTACTGAAATGATCATTGGGAACATA
ACGCGAAGTTTGCCGTGTGCAGAGGCTCGCAGAATACCGCGTAGCTGGTCACGTAGAATTTCACGGCGAT
CTAAGCTGATACGCACGGCACGCCAACCCAAGAATGGGTTCATCTCTTTTGGGAGATCCATGTACGGTAG
ATCTTTGTCGCCGCCGATGTCCATGGTGCGGATGATAACCGCTTGGCCATTCATCGCTTCCGCGACTTCT
TTGTAGGCTTGGTACTGTTCTTCTTCTGTTGGCAGGGCATCACGATCCATGAACAGGAATTCAGTACGGT
ATAGGCCGACACCTTCACCACCGTTACGGATGATACCGTCACAGTCTTTCACGGTACCGATGTTGCCACA
CACTTCAACGCGATGGCCGTCTAGCGTTTCTGCTGGAAGATCTTTCAGCTTAGCGAGCTCTTCTTTTTCC
GCTAAGAAAGCCGCTTTAACCGCTTTGGCTTCTTCAATTTGTGCTTGAGTTGGATTCACAATGATCTTGT
TGTTCATTGCGTCCAGAATTAATGTGTCGCCATTTTTCACTTTCTTAGTGATGTCGTTAGTACCGACAAT
CGCTGGCAGCTCTAGAGAGCGAGCCATGATAGAAGTGTGAGAGGTACGGCCGCCAATATCACATGCAAAA
CCGAGAACGTAGTTCAGGTTAATCTGCGCAGTTTCAGAAGGCGTTAAATCGTAGGCAACAAGGACAACTT
CTTGATCGATTTCGCTCAGCGATACGATGTGCATGCCCAGAGCATTTTTTACAAAACGTGTACCGATATC
ACGGATATCTGTTGCACGTTCTTTGAGATATTCATCGTCTAAAGATTCAAGCGCAGTGGCTTGCTCTTCG
ATAACGGTATGAATCGCGTTATCGGCAGACATTTTTTCTTTTTTGATGAGGGCTAAAATCTCTTCTTCTA
GCTCTTCATCTTCAAGCAACATGATATGGCCTTCAAAGATGGCTTCTTTTTCTTCACCAAAAGTTTCAAG
TGCTTTTTGTTTGATCACTTCTAACTGCGCAGAAGATTTGTCACGCGCAGTGTAAAAGCGCTCAACTTCG
GCTTCTACTTGATCGTCAGAAATGGTGTTTGTGTTTAGGACAATTTCATCTTCTTGAAGAAGTAATGCTT
TACCAATAGCAATACCTGGAGATGCTAGAATGCCTGAAATCA
Protein Sequence 
>gi|15640981|ref|NP_230612.1| phosphoenolpyruvate-protein phosphotransferase [Vibrio cholerae O1 biovar El Tor str. N16961]
MISGILASPGIAIGKALLLQEDEIVLNTNTISDDQVEAEVERFYTARDKSSAQLEVIKQKALETFGEEKE
AIFEGHIMLLEDEELEEEILALIKKEKMSADNAIHTVIEEQATALESLDDEYLKERATDIRDIGTRFVKN
ALGMHIVSLSEIDQEVVLVAYDLTPSETAQINLNYVLGFACDIGGRTSHTSIMARSLELPAIVGTNDITK
KVKNGDTLILDAMNNKIIVNPTQAQIEEAKAVKAAFLAEKEELAKLKDLPAETLDGHRVEVCGNIGTVKD
CDGIIRNGGEGVGLYRTEFLFMDRDALPTEEEQYQAYKEVAEAMNGQAVIIRTMDIGGDKDLPYMDLPKE
MNPFLGWRAVRISLDRREILRDQLRGILRASAHGKLRVMFPMIISVEEIRELKNAIEEYKAELRTEGHAF
DENIEIGVMVETPAAAAIAHHLAKEVSFFSIGTNDLTQYTLAVDRGNEMISHLYNPLSPAVLTVIKQVID
ASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSGISIPKVKKVIRNANYAEIKAMAEEALALPTAAE
IEACVDKFIAAKA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC0965 mutant is attenuated in mice (Merrell et al., 2002).
COG COG1080G, under G: Carbohydrate transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].