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VC1639

Victor ID 2423
Gene Name VC1639
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2613770
NCBI Protein GI 15641644
Locus Tag VC1639
Genbank Accession AE003852
Protein Accession NP_231276
Other Database IDs UniProtKB-ID: Q9KRK1_VIBCH
UniRef100: UniRef100_A5F7P5
UniRef90: UniRef90_A5F7P5
UniRef50: UniRef50_Q7MLK6
UniParc: UPI00000C3061
EMBL: AE003852
EMBL-CDS: AAF94790.1
RefSeq_NT: NC_002505.1
HSSP: P02933
GenomeReviews: AE003852_GR
KEGG: vch:VC1639
TIGR: VC_1639
HOGENOM: HBG700828
OMA: EMVGNLV
ProtClustDB: CLSK874470
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 1764913
Gene Ending Position 1766301
Gene Strand (Orientation) +
Protein Name sensor histidine kinase
Protein pI 6.66
Protein Weight 48802.29
Protein Length 462
Protein Note similar to PID:929823; identified by sequence similarity; putative
DNA Sequence 
>gi|15640032:1764913-1766301 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
CTTGGGTATCAGTTGCATGCCAATTAAATCTCGGGCGTTACGTCATCTCAGCCTAAAAACCCGCTTGCTC
CTTGCTGCGGCACTATGGCTGGGCGCGATGATCTTGGCCGCCGGCTATTTGATCCCAAATCTCATCCATC
AATATTTGCTGGAAGATGTGCAAAACCAGTTGCAACTGTCGATGGATGAGATCACCGCCAACTTGGAAGC
CAATCCACAAGGACAATTAACCCTCACCACTCGACTTGCGGATCCCCGTTTTACCCAGCCTTATAGTGGC
CTTTACTGGTCAGCCACTTTAGGCGATCAAACGCTTCGCTCACGCTCGTTGTGGGATCGCTTTTTGACCG
AAGAAACCCATGTTCACGGTACGATTTATCTTGGCGCGAAAGAGGAATCGTTAATTGTATTAAAGCGTAC
GGTTTATCTGCCCGAATTTTCACAACCCATCACAATCACGATAGGCTTAGATGATGCCCCGCTAAAAGCC
ACGCTACAGCGCGTGAGCAAAGAGTTGTGGATGATTTTGGCTCTATTGTTCAGCGGGATACTCGTTTTAA
CTGGCGTACAAGTGACGTGGTCACTCCGCCCACTTTCGAAAATGCAGCGCGAACTCTCAGCCTTGCGAGA
TGGCCAGCAAAATGCGTTGAATGGCGATTACCCACAAGAGATTTCACCGCTAGTCAATGATCTCAACGCT
CTCCTCTTTCATTACCAAGAGCTGCTTGAGCGAGCCAGACACCATGCGGGGAACTTATCCCACGCATTAA
AAACACCACTTTCTGTGCTCAAAAACGAAGTCACTCAGTTGAATGATGCCCAGCTCAGAATCCAGTTACA
GCCTTCTGTTGAGCAGATCCAGCAGCAAATTGACTACCATCTAGGGCGTGCTCGTATGGCGGGTTCCGCC
AATATTCTTTCGGTTAAAACCGCACCCAGTGCGCGAGTCGATGCTATTTCACAAGCATTTGATAAGGTTT
ACGCTGAACGTGGAATCACCTTGGTGAATGAGCTGGATTCGGACTTAGAAGTGGCCGTTGAACCGACTGA
CCTAGATGAAATGATCGGTAACCTTCTGGAAAACAGCTACAAATGGGCCAACAGCTTAATTCGTGTACAC
AGCCAAATACTGAGTGACGATTGGGTACAGATCTGCGTGGAAGACGATGGCGCAGGCATCAGTGCAACGA
ACCGCGAAAAAGCCCTCAAACGCGGAGTGCGCTTGGATGAAACCACGCCCGGCACTGGGCTTGGGCTTAA
TATTGTGAGTGAAATGGCGCACAGTTATCGTGGAGCATTGGCTTTAGGAGAGAGTCAGTTAGGCGGCTTA
AAAGCCACTCTGACCTTAAAACAACCCACTCGCGCAGCCAAAGCCGTCAAATCCCATTA
Protein Sequence 
>gi|15641644|ref|NP_231276.1| sensor histidine kinase [Vibrio cholerae O1 biovar El Tor str. N16961]
MGISCMPIKSRALRHLSLKTRLLLAAALWLGAMILAAGYLIPNLIHQYLLEDVQNQLQLSMDEITANLEA
NPQGQLTLTTRLADPRFTQPYSGLYWSATLGDQTLRSRSLWDRFLTEETHVHGTIYLGAKEESLIVLKRT
VYLPEFSQPITITIGLDDAPLKATLQRVSKELWMILALLFSGILVLTGVQVTWSLRPLSKMQRELSALRD
GQQNALNGDYPQEISPLVNDLNALLFHYQELLERARHHAGNLSHALKTPLSVLKNEVTQLNDAQLRIQLQ
PSVEQIQQQIDYHLGRARMAGSANILSVKTAPSARVDAISQAFDKVYAERGITLVNELDSDLEVAVEPTD
LDEMIGNLLENSYKWANSLIRVHSQILSDDWVQICVEDDGAGISATNREKALKRGVRLDETTPGTGLGLN
IVSEMAHSYRGALALGESQLGGLKATLTLKQPTRAAKAVKSH
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC1639 mutant is attenuated in mice (Merrell et al., 2002).
COG COG0642T, under T: Signal transduction mechanisms
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].