Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

tolBfrom Vibrio cholerae O395

Victor ID 2338
Gene Name tolBfrom Vibrio cholerae O395
Sequence Strain (Species/Organism) Vibrio cholerae O395
NCBI Gene ID 5135619
NCBI Protein GI 147674437
Locus Tag VC0395_A1429
Protein Accession YP_001217372.1
Taxonomy ID 345073
Chromosome No 2
Gene Starting Position 1530222
Gene Ending Position 1531574
Gene Strand (Orientation) -
Protein Name translocation protein TolB
DNA Sequence 
>gi|147673035:1530222-1531574 Vibrio cholerae O395 chromosome 2, complete sequence
GTTATAAAAACGGTGACCATGCTGGAGCACGAACGCGCCCATTGGTTGCCGGTAATCTTGCTTTAAAGCG
TCCATCAATGGATACCATCGACAAGACGTTGGCCTTATTGTAGATGGAGCTATAAATCACCATACCACCA
TTCGGCGCAATACTTGGGGACTCATCTAACAAGGTTTTTGTCAGAATCTGCATTGCCCCTGTTTCTAAAT
CCTGCTTCGCGAGATTGAAGCCGGAATCACTACGATTCACCATCACCAAGAATTTTCCATCCGGTGTAAT
TTGGCCACCCAAGTTTTGGCTACCTTGCCAAGTTAAACGCTTGGTTTCACCGCCGGATAAATTTACTTGA
TAAATCTGTGGTTTACCACCCCGATCTGAAGTGAAAATTAAAGATTTACCATCTGGATGCCAGAAAGGTT
CGGTGTTGTTGGAACGGCCACTAGTCACCTCTGTTAAGCGACGTGTAGCCAAGTCCATCGTGTAGACCTG
TAAATTACCAGTTTTTGATAAAACCAGCGCTAGCGTTTTACCATCTGGTGAGAATCTGGGTGCACCATTA
TGACGTGGGAATGACGTCAGCTTCTCTCGCTTCCCACTGTAGATGTTCATCATGTAAATTTCGGCTTGTC
CGTTTTGGAAACTCACGTAAGCCAAAGTCTGACCATCAGGTGACCAAGCAGGTGACATAAGCGGCTGCTT
AGAACGAAGTACAAGACGTTCGTTATAGCCGTCATAATCAGCAATTCTCAGTTGATAAGGATACGGATCC
TTATCATTGACCACAACGTAAGCGATGCGCGTTAAGAAGGCGCCGCGTTCACCGGTCAATTCCTCATAAA
CCAAGTCCGCAATACGGTGGGCATATTCACGCATTCTTGATGCAGGAACGGTCGCCACTTTATTAAACAA
AACATGATCTTTAGATAGCACCAATTGACCATCTTGAGACAGAGCTTTGCTTTGGCCTTGAGTCAGTTGT
CCACGCACAATGTCAACCAGTTGATAACTAATTACATAGCTACCTTCCGCATTTTGCGTGATCGTACCCG
TCAATAATGAATCGACCCCCATAGATGTCCATTTGCCAAAGTTAACCTGCTCTTCGCTATAAGGCGTCTG
TGGCATTTTGCTGGTCGGAACTGGGCTAAATTTACCACTGCGCTGTAAGTCAGAGGCAATCACCGCAGAA
ACGTCTTCAGGCAACTTGGTTGCGCCTTCCCATTTGAAAGGAACTATCGCAATCGGACGTGCAGAATCAA
TACCGTCAGTAATAACTAGCTCCAATGCTGCATTCGCAATATTGGAAAAACCGGTACCGATGAGCATCAA
AACAAAAACTAATCGCTTAAACA
Protein Sequence 
>gi|147674437|ref|YP_001217372.1| translocation protein TolB [Vibrio cholerae O395] MFKRLVFVLMLIGTGFSNIANAALELVITDGIDSARPIAIVPFKWEGATKLPEDVSAVIASDLQRSGKFSPVPTSKMPQTPYSEEQVNFGKWTSMGVDSLLTGTITQNAEGSYVISYQLVDIVRGQLTQGQSKALSQDGQLVLSKDHVLFNKVATVPASRMREYAHRIADLVYEELTGERGAFLTRIAYVVVNDKDPYPYQLRIADYDGYNERLVLRSKQPLMSPAWSPDGQTLAYVSFQNGQAEIYMMNIYSGKREKLTSFPRHNGAPRFSPDGKTLALVLSKTGNLQVYTMDLATRRLTEVTSGRSNNTEPFWHPDGKSLIFTSDRGGKPQIYQVNLSGGETKRLTWQGSQNLGGQITPDGKFLVMVNRSDSGFNLAKQDLETGAMQILTKTLLDESPSIAPNGGMVIYSSIYNKANVLSMVSIDGRFKARLPATNGRVRAPAWSPFL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tolB mutant is attenuated in mice (Merrell et al., 2002).
COG COG0823U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].