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VC1675

Victor ID 2424
Gene Name VC1675
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2613806
NCBI Protein GI 15641679
Locus Tag VC1675
Genbank Accession AE003852
Protein Accession NP_231311
Other Database IDs UniProtKB-ID: Q9KRG7_VIBCH
UniRef100: UniRef100_A1F4F3
UniRef90: UniRef90_A1F4F3
UniRef50: UniRef50_Q7MLN2
UniParc: UPI00000C3083
EMBL: AE004245
EMBL-CDS: AAF94825.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC1675
TIGR: VC_1675
HOGENOM: HBG742930
OMA: PAENHEY
ProtClustDB: CLSK874493
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 1809978
Gene Ending Position 1811009
Gene Strand (Orientation) -
Protein Name multidrug resistance protein, putative
Protein pI 6.31
Protein Weight 34663.48
Protein Length 343
Protein Note similar to GB:L11616 PID:438853 SP:P52477; identified by sequence similarity; putative
DNA Sequence 
>gi|15640032:1809978-1811009 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
CCTACAGCCCTCGCTCCTTGACCCATTCACGCACTTTTATGCCCTCGGTCACGCCACTGACACCGGAAAT
AATGATCCGGTCGCCATCATTTAAGCCTGTAAGCACTTGGCGTTGTTCATTCAAAGTGACCGCAGCTTTA
CTGACCAGCCCCGCGTCATCGACTCGCCATACGTATTTTCCCCCTTGCTCTGCAAACAATGCAGAAGTGG
GGATCACCGTCGCGCTACCGCTCGGAGCCATGAGGCTTACACGCCCCGCCATACCCGGCAAAATGCCGAC
ATCATTGGGTCTTTCCATCACCATAGTCACTTTATAGGAGCGGGTTTTGGAATCGGCCTCGGTATCTATC
TCTTGAAATTGCAACGGATATTGGCGGTTAGGGAACGAGTCAAACACCATATGCGCTTCTACACCATCGC
GAGAAAAGCGATTAAGCAAATGATCGGGAAGGAGAAACTGCACTTTGAGCAGTTGATTGGTTTGAATATT
CATCACCCCTTGCTTGGCTGCGACATACTCATACTGCTCTGCTGGGATCAGCGAAATAGTGCCATCATAA
GGGGCGATCAATTGGGTATAACGCAGATTGGCTTTGGCTTGTTCCCAGGTGGCTTTCGCGGAATTGTGAT
TGGCTTGAGCTTGGTCGAAATCCTGCTCGGAAACGACTTTGTCTTGTCGTAATCGCTGTGCCCGCTGAAA
TTGCACATCGGCTAATTGAAAATTGGCGCTGGCTTGCTGTTCTAACAACGCATATTCGTCAGGGTTGAGT
CTGGCAAGTACCTCACCTTTCTTCACCTCTTGTCCGGCTAAAACATCAATGGTTTGTAGTTGTCCGGGTA
CACGGAAAGCGAGCACCGCGCGATCGCCAGCCGCCGTAGTGGCTGGAAATTGGCGAGAAAAGGTGTTGTT
ACCTACGGACACAGTCGTCAATTTAGCTGGCCGCGAATCGGGCTCAGGCACGGGAGGAAGCTCTTTTCCA
CACCCCACCAGCAAAGTGGAGCAGATAGAAAAGGCCAAAAGGGTTTTGTTCA
Protein Sequence 
>gi|15641679|ref|NP_231311.1| multidrug resistance protein, putative [Vibrio cholerae O1 biovar El Tor str. N16961]
MNKTLLAFSICSTLLVGCGKELPPVPEPDSRPAKLTTVSVGNNTFSRQFPATTAAGDRAVLAFRVPGQLQ
TIDVLAGQEVKKGEVLARLNPDEYALLEQQASANFQLADVQFQRAQRLRQDKVVSEQDFDQAQANHNSAK
ATWEQAKANLRYTQLIAPYDGTISLIPAEQYEYVAAKQGVMNIQTNQLLKVQFLLPDHLLNRFSRDGVEA
HMVFDSFPNRQYPLQFQEIDTEADSKTRSYKVTMVMERPNDVGILPGMAGRVSLMAPSGSATVIPTSALF
AEQGGKYVWRVDDAGLVSKAAVTLNEQRQVLTGLNDGDRIIISGVSGVTEGIKVREWVKERGL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC1675 mutant is attenuated in mice (Merrell et al., 2002).
COG COG0845M, under M: Cell wall/membrane/envelope biogenesis
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].