Victors

VC2390
Victor ID	2404
Gene Name	VC2390
Sequence Strain (Species/Organism)	Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID	2613059
NCBI Protein GI	15642387
Locus Tag	VC2390
Genbank Accession	AE003852
Protein Accession	NP_232020
Other Database IDs	UniProtKB-ID: CARA_VIBCH UniRef100: UniRef100_Q9KPH8 UniRef90: UniRef90_Q7MNU1 UniRef50: UniRef50_A4SXM1 UniParc: UPI0000126F67 EMBL: AE003852 EMBL-CDS: AAF95533.1 RefSeq_NT: NC_002505.1 GenomeReviews: AE003852_GR KEGG: vch:VC2390 TIGR: VC_2390 HOGENOM: HBG286341 OMA: FTYPELG ProtClustDB: PRK12564
Taxonomy ID	243277
Chromosome No	I
Gene Starting Position	2557295
Gene Ending Position	2558434
Gene Strand (Orientation)	-
Protein Name	carbamoyl phosphate synthase small subunit
Protein pI	5.89
Protein Weight	38540.58
Protein Length	379
Protein Note	catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers
DNA Sequence	>gi\|15640032:2557295-2558434 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome ATTAAGCGCGGAATTGTTTAATCAGTTCAATAAAGTGGTCAAACAGCGGTGCTGCATCGTGTGGACCTGG GCTTGCTTCTGGGTGGCCTTGGAAGCTAAACGCTGGCTTGTCGGTACGATGAATCCCTTGCAGTGAACCA TCAAACAGCGATTTGTGGGTTGCACGCAGGTTGTCAGGCAGAGTCGCTTCATCGGCTGCAAAACCGTGGT TTTGCGAGGTGATCATCACCACACCGCGATCCAAATCTTTCACTGGATGGTTTGCACCATGGTGACCGAA CTTCATTTTTACTGTTTTCGCGCCGGAGGCGAGTGCCAGAATTTGGTGACCTAGACAGATCCCAAAAACA GGAATGTTTTTCTCAAGGAAAACGCGTGTGGCTTCAATCGCATAAGTACATGGCTCTGGGTCGCCTGGGC CATTGGATAGAAACACACCGTCTGGATTAAGGGCGAGCACGTCTTCTGCAGAGGTCTGCGCCGGTACCAC AGTTAAGCGGCAGCCACGATCCACCAACATACGTAGGATGTTACGCTTCGCACCAAAATCGTAAGCCACA ACATGGTAAGGCAGCTCGCTGTCCGCTTTCGCTTCAGGTAGGCCGCCTTCTAGCGTCCATGAGCCTTGTT TCCACGCATACGCTTCTTTGGTGGAAACCACTTTCGCGAGATCCATGCCTTTCAGGCCCGGAAACTCTTT CGCTTTCGCCAGTGCTAATGCTTCATCCAGATTATCGCCCGCCATGATGCAGCCGTTCTGTGCGCCTTTC TCACGCAAGATACGAGTCAGTTTACGGGTATCAATGTCAGCAATACCGACAATGTTTTGTGACTTGAGAT AATCAGAGAGGGATTGTTCACTGCGGAAGTTAGAAGCGATAAGAGGGAGATCGCGAATCACAAGGCCTTG AGCATGAATCGCGGTGGATTCTTCGTCTTCGGAGTTGGTTCCGGTATTGCCAATGTGAGGATAAGTAAGA GTAACGATTTGCTGGGAATAAGAAGGATCAGTGAGGATTTCTTGGTACCCCGTCATCGAGGTATTGAAAA CGACTTCACCGACGGAAATACCATCTGCCCCGATGGACACTCCGCGGAACACTGTCCCATCTTCTAGGAC TAACAGTGCTGATTTACTCA
Protein Sequence	>gi\|15642387\|ref\|NP_232020.1\| carbamoyl phosphate synthase small subunit [Vibrio cholerae O1 biovar El Tor str. N16961] MSKSALLVLEDGTVFRGVSIGADGISVGEVVFNTSMTGYQEILTDPSYSQQIVTLTYPHIGNTGTNSEDE ESTAIHAQGLVIRDLPLIASNFRSEQSLSDYLKSQNIVGIADIDTRKLTRILREKGAQNGCIMAGDNLDE ALALAKAKEFPGLKGMDLAKVVSTKEAYAWKQGSWTLEGGLPEAKADSELPYHVVAYDFGAKRNILRMLV DRGCRLTVVPAQTSAEDVLALNPDGVFLSNGPGDPEPCTYAIEATRVFLEKNIPVFGICLGHQILALASG AKTVKMKFGHHGANHPVKDLDRGVVMITSQNHGFAADEATLPDNLRATHKSLFDGSLQGIHRTDKPAFSF QGHPEASPGPHDAAPLFDHFIELIKQFRA
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: VC2390 mutant is attenuated in mice (Merrell et al., 2002).
COG	COG0505EF, under E: Amino acid transport and metabolism; F: Nucleotide transport and metabolism
References	*Merrell et al., 2002:* Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].


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VC2390