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acfB from Vibrio cholerae M66-2

Victor ID 3856
Gene Name acfB from Vibrio cholerae M66-2
Sequence Strain (Species/Organism) Vibrio cholerae M66-2
NCBI Gene ID 7772078
NCBI Protein GI 227081017
Locus Tag VCM66_0797
Protein Accession YP_002809568.1
Other Database IDs UniProtKB-ID: C3LT91_VIBCM
UniRef100: UniRef100_C3LT91
UniRef90: UniRef90_C3LT91
UniRef50: UniRef50_A5F386
UniParc: UPI0000ED723D
EMBL: CP001233
EMBL-CDS: ACP05117.1
RefSeq_NT: NC_012578.1
GenomeReviews: CP001233_GR
KEGG: vcm:VCM66_0797
OMA: FNIASET
ProtClustDB: CLSK793817
Taxonomy ID 579112
Chromosome No I
Gene Starting Position 858945
Gene Ending Position 860825
Gene Strand (Orientation) +
Protein Name accessory colonization factor AcfB
DNA Sequence 
>gi|227080237:858945-860825 Vibrio cholerae M66-2 chromosome I, complete genome
AATGAAGTTTTCTATCAAGTTACTAATGATTTTTACATCAATTATAATTACTATTTCATCTATCCTTACT
TACTTTCAGATGCATGGAACCAATGAATATCTTGATCGTACGATAAAAGATACTATTTCTGAAACGCTAG
ACTCTTTGGAAGATAAAATAAATCTTTCTATTGAGTCCAAGGTCGATGTGTCAAAATCTGTTATCGACAT
TTATGAAAATTTACTGGAGGGGGAATCCCCTCTCAGTAAATTTAAGGATGTTGATGTCAATCATCTTTCA
AATGTTTTTCAATTGTTCGGATATGCTGATGAAAGAACAGGAGAGATCATTACTAATGACCCAAACTTTA
AAGTGCCTACAGGATTCGATCCAAGGACTCGATCGTGGTATTTAAATGCAAAAAAATTGAATACCTTTAG
TTTGTCTGAGCCGTATGTCGATCTCATTACAGAGAAGTTAATGGTGACAACAAGTGCACCAATATATAAT
AAAAACGATTTAACAGGAGTTATATTTTTTGATATACCACTAGATGACGTTCAGGAATTAATTAAAAGCT
ACAATCCATTTGATGCCGGCACGATTTTTATCGTTGATAACAGTGGGAAAATAATTTTCGGTAATAAAAA
TGATATATCGGGTAAAAATTTATTTGGAGACTTTGATAGCTTCCCTCTATCGGTAAGTGAGTCAAAAACG
AAAGATAAAAATGGGGTAAATTACGATGTATTCATCAAAATGTCAGACTTTGGCGGTTGGAATCTTGTTT
CTATTATCGACCATGATAAAGCACGCTCTGATATTATCACGTTGAGAAACAATAGTATATTTACTGCCGT
CATTTTAGCAAGTGTTTTCTTTGCTATCTTGTTGTTTACTATGCGGTTAATGCTGAAGCCATTGCATCAA
TTAACCGATGCAATGGTAAATATTTCATCGGGCAGTGCTGATCTTACGGTTCGTATCCCGAATAGTACGG
ATCAAGAGTTTTCAAAAATAATAAATTCCTTTAACATTTTTGTTGGTAATCTGCAATCTATTGTGTCGGA
GGTTAAAATGAACTCAGAAAAAATAAATTGCATAACTACTGAAACACAAGAGCTAGTCGAAGTTTGCAAT
AATAGCGTAGCTGATCAGTATCGTGAACTTGATATGCTAGCTAGCTCAATGAATGAGATGGTGGCAACAT
CTAATCAGATTGCACAAATTACATCCGAAGCATCAGAGATCACATCTAAGATTAACGGTCAAGTGAATGA
AGGAGTCGGTGCTGTTTCTTCTGTTACCGAAAGTGTAGGTAATTTAGTTGAGAAGTTGGATAAGACGAAA
TCTGTTATCCAAGATCTTAATCGCCAAACTCAAAATATAGATGTTATTTTGAAGGCTATTAATGATATTG
CTGACCAAACAAACCTTCTTGCTCTTAATGCTGCAATTGAGGCTGCACGAGCTGGGGAAAATGGACGAGG
TTTTGCTGTGGTTGCTGATGAGGTACGCAGCCTAGCAATAAAGACACAAGAGTCTACTAAAAATATAGGA
AGTATTATCCATATATTACAAGAAAACTCTTTGCTATCCGTTCATGTTATGGATGAAAGTTTTAATATTG
CCTCTGAAACTATGACTATATCAGCTGATTCAAAACAATGTTTAGACAATATTAGTCAATCAGTAATACA
AATTGTTGATATCACAAATCAAGTAGCTACAGCTGCTTACGAACAAAGTCACGTATCAGAGGAAATAAAC
AGCAACTCTATTTCTATAAAAGATAAAGCAGATACCTTATCAAGTTTGGGTAATAAGATTTCTCAACAGG
CTTATTCTCAAAAAGCACTGATTGGTCATCAAGATGATTTAATCAGTAAGTTTATCATTTA
Protein Sequence 
>gi|227081017|ref|YP_002809568.1| accessory colonization factor AcfB [Vibrio cholerae M66-2] MKFSIKLLMIFTSIIITISSILTYFQMHGTNEYLDRTIKDTISETLDSLEDKINLSIESKVDVSKSVIDIYENLLEGESPLSKFKDVDVNHLSNVFQLFGYADERTGEIITNDPNFKVPTGFDPRTRSWYLNAKKLNTFSLSEPYVDLITEKLMVTTSAPIYNKNDLTGVIFFDIPLDDVQELIKSYNPFDAGTIFIVDNSGKIIFGNKNDISGKNLFGDFDSFPLSVSESKTKDKNGVNYDVFIKMSDFGGWNLVSIIDHDKARSDIITLRNNSIFTAVILASVFFAILLFTMRLMLKPLHQLTDAMVNISSGSADLTVRIPNSTDQEFSKIINSFNIFVGNLQSIVSEVKMNSEKINCITTETQELVEVCNNSVADQYRELDMLASSMNEMVATSNQIAQITSEASEITSKINGQVNEGVGAVSSVTESVGNLVEKLDKTKSVIQDLNRQTQNIDVILKAINDIADQTNLLALNAAIEAARAGENGRGFAVVADEVRSLAIKTQESTKNIGSIIHILQENSLLSVHVMDESFNIASETMTISADSKQCLDNISQSVIQIVDITNQVATAAYEQSHVSEEINSNSISIKDKADTLSSLGNKISQQAYSQKALIGHQDDLISKFII
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: acfB mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice (Peterson and Mekalanos, 1988).
COG COG0840NT, under N: Cell motility; T: Signal transduction mechanisms
References
Peterson and Mekalanos, 1988: Peterson KM, Mekalanos JJ. Characterization of the Vibrio cholerae ToxR regulon: identification of novel genes involved in intestinal colonization. Infection and immunity. 1988; 56(11); 2822-2829. [PubMed: 2902009].