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purD from Vibrio cholerae O395

Victor ID 2350
Gene Name purD from Vibrio cholerae O395
Sequence Strain (Species/Organism) Vibrio cholerae O395
NCBI Gene ID 5136447
NCBI Protein GI 147673352
Locus Tag VC0395_A2652
Protein Accession YP_001218530.1
Taxonomy ID 345073
Chromosome No 2
Gene Starting Position 2804678
Gene Ending Position 2805967
Gene Strand (Orientation) -
Protein Name phosphoribosylamine--glycine ligase
DNA Sequence 
>gi|147673035:2804678-2805967 Vibrio cholerae O395 chromosome 2, complete sequence
CTTACTTGGCTTGCTCACGCGCAATCGCGCGATAACCGATATCGCGGCGGCAGAACATACCATTCCAGTG
GATTTGATCCGCCAGTTGGTAAGCGCGTTGCTGCGCTTCTAATACGGTATTGCCCAGCGCCGTGGCACAC
AATACGCGACCGCCATTCGTAACCACTTGGTCGCCTTGGGTTTCGGTGCCTGCGTGGAACACTTTTTGTC
CTGCGCTTTCTTGAGTCGGTAGACCTGAAATCACCTCACCTTTGGTGTAATCGCCAGGGTAGCCGCCAGC
GGCGAGAACCACACCGATCGAGGCGCGTGGATCCCACTTCGATTCCACTTGATCCAGTTTGCCCGCAATT
GCTGCTTGGCACAGCTCAACCAGATCCGATTGCAGACGCATCATGATCGGTTGGGTTTCTGGGTCACCAA
AGCGGCAGTTGTACTCAATCACTTTCGGTGCACCAGTGCTATCTATCATCAAACCCGCGTAGAGGAAGCC
TGTGTAGGTGTTGCCTTCGGCTGCCATGCCGCGCACGGTTGGGTAAATCACTTCACGCATTACGCGATCA
TGGACGTCCTGTGTCACCACTGGCGCTGGTGAGTAAGCACCCATACCGCCGGTGTTCGGGCCAGTATCGG
CATCGCCCACGCGTTTGTGATCTTGGCTGGTGGCCATAGGCAGGACGTTTTCACCATCAACCATCACGAT
AAAGCTCGCTTCCTCTCCATCAAGGAATTCTTCAACCACCACACGGCTGCCTGCTGAACCAAAGGCATTG
CCAGCTAGCATGTCTTGAATTGCGTTTTCGGCCTCTTGCAGAGTCATCGCAACAATTACGCCTTTGCCCG
CCGCTAAACCGTCGGCTTTCACGACAATCGGCGCACCTTTTTTACGCACATAAGCCAGAGCTGGCTCAAT
TTCAGTGAAGTTGGCGTAAGCCGCTGTTGGAATGTGATGGCGAGCGAGGAAATCTTTAGTGAAGGCTTTG
GAGCCTTCTAGTTGCGCCGCGCCTTGGGTGGGGCCAAAAATCGGTAAACCTGCAGCGCGAAACGCATCGA
CCACACCAATCACCAGTGGTGCTTCTGGGCCAACGATGGTCAGCTCAATCGCTTTATCTTGAGCAAAGGC
AACCAGTGCTGGAATGTCGGTGATGCCAATGTTGACGTTTTGCACCTTGTGCTCAAGGGCAGTACCCGCA
TTGCCGGGCGCGACGTAAATAGTGTCAACTTGTGGGTTTTGTGCCACTTTCCACGCCAGTGCGTGTTCGC
GACCGCCAGAGCCGATGATGAGAACTTGCA
Protein Sequence 
>gi|147673352|ref|YP_001218530.1| phosphoribosylamine--glycine ligase [Vibrio cholerae O395] MQVLIIGSGGREHALAWKVAQNPQVDTIYVAPGNAGTALEHKVQNVNIGITDIPALVAFAQDKAIELTIVGPEAPLVIGVVDAFRAAGLPIFGPTQGAAQLEGSKAFTKDFLARHHIPTAAYANFTEIEPALAYVRKKGAPIVVKADGLAAGKGVIVAMTLQEAENAIQDMLAGNAFGSAGSRVVVEEFLDGEEASFIVMVDGENVLPMATSQDHKRVGDADTGPNTGGMGAYSPAPVVTQDVHDRVMREVIYPTVRGMAAEGNTYTGFLYAGLMIDSTGAPKVIEYNCRFGDPETQPIMMRLQSDLVELCQAAIAGKLDQVESKWDPRASIGVVLAAGGYPGDYTKGEVISGLPTQESAGQKVFHAGTETQGDQVVTNGGRVLCATALGNTVLEAQQRAYQLADQIHWNGMFCRRDIGYRAIAREQAK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: purD mutant is attenuated in mice (Chiang and Mekalanos, 1998).
COG COG0151F, under F: Nucleotide transport and metabolism
References
Chiang and Mekalanos, 1998: Chiang SL, Mekalanos JJ. Use of signature-tagged transposon mutagenesis to identify Vibrio cholerae genes critical for colonization. Molecular microbiology. 1998; 27(4); 797-805. [PubMed: 9515705].