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tcpT from Vibrio cholerae M66-2

Victor ID 3854
Gene Name tcpT from Vibrio cholerae M66-2
Sequence Strain (Species/Organism) Vibrio cholerae M66-2
NCBI Gene ID 7772073
NCBI Protein GI 227081012
Locus Tag VCM66_0792
Protein Accession YP_002809563.1
Other Database IDs UniProtKB-ID: C3LT86_VIBCM
UniRef100: UniRef100_A5F381
UniRef90: UniRef90_P29480
UniRef50: UniRef50_P29480
UniParc: UPI00000B4509
EMBL: CP001233
EMBL-CDS: ACP05112.1
RefSeq_NT: NC_012578.1
GenomeReviews: CP001233_GR
KEGG: vcm:VCM66_0792
OMA: HAIRRIN
ProtClustDB: CLSK793812
Taxonomy ID 579112
Chromosome No I
Gene Starting Position 853606
Gene Ending Position 855117
Gene Strand (Orientation) +
Protein Name toxin co-regulated pilus biosynthesis protein T
DNA Sequence 
>gi|227080237:853606-855117 Vibrio cholerae M66-2 chromosome I, complete genome
GATGTCAATTGATATAAAGTATTTAAGTCGTATTGATATAGATCGTGAGGAGTTTTTCTTTAAAGACTCG
AGATTAATGTGTAAGAAATTCGATGAAGAGCGTGAGGTATTAACTCTTCTCGAATTCGATACAAAATTTC
GGGTCAATCTTCTGAAGAAAGATAAAGTTTATAAGTATTTCTTAGTTTCAGATGCAAATCATAAATTATT
AATAGCGAATCTTGTTACCGAGCAGCAAGCTAAAGACTTAAGTTTTATAGAAAAAGATATAATGAAAATT
GCATCATCTGCTACAGCTTATGGTGCAAGTGACATCCACTTCATCCGAGAGGATAGGATTTGTAAAATAA
AATTCCGTGTGAATGGCACAATGATCGACTATAGAGAAATATTAAGTTCAGAAGCCGATTCGCTAATGTT
TGTTCTATACAATGTGATGGCAACAACGAAAGAAACGACGTGGAACCGAAAACTACCTCAAGATGCAAAT
ATTATTCTTGTGATCAACGAAAAGGCATATCGCTTTCGTTACGCACATATGCCTTTATTTGGTGAGGGAG
GGAAAAACTATCATGCGGTAGTTCGTATTATCTATCCTTCAAATAATTTTGTTTGTACAAACTATCAAGA
TATTGGGTATAACGAGGCTGATACCGATGCGATTGCAAGAATTCTAAATACATCTTATGGATTGTTCATT
GTTTCCGGAACAACAGGTTCTGGTAAATCAACATCTTTGAAAAAGTATATAGAATTACTTTTCTTTAATA
AATATAAGGGAAAAGGATGTTTTGTCACCGTTGAAGATCCTGTCGAGTATTTAATTTCTGGAGCACAGCA
AAGCTCAATTGTTGCCGATAATGATGATAAAACAAAGAACCCATTTGCTGATGCGGTACGTTCAGCGATG
CGTCGAGATCCGGACGTTATTATGATCGGTGAAATTCGTGATAAACCTACCGTTGAGGCTCTATCAAGTG
CTGTAGAAAGTGGCCACTATTGTCTTACGACCATCCATGCAGGTTCTGTTGTTTCTGTTTTACAAAGACT
TTCAGGATTAGGGATGAAGGCTGACAAAATAGCATCACCTGGATTTCTGGCTGGTATTACAAGTCAGAAA
TTAATTCCCGAACTTTGCCCAAGTTGTAAAGTTTCCTTTGTTGATGAACGTTATCAGCGTGCTGTATTTA
GCGCGAATGAAAATGGCTGTGAGGCATGTAATCATTCTGGGTTTAAAGGAAGGCTGCTTTTATTAGAAAC
ATTAGTCCCAACAGTTGAAGATTTAGAGCTAGTGGCGAGTGAAAACTGGGTTTCCCTTTATCGTAAATAT
CGGGAGCGACGCTTTATAAAAACTGGAAAAAAAGGTCTTGGTGAAGGCTTCAGCATTAAAGATAAAGCTT
ATTACAATGTTTTAAAAGGTAAAGTGTGTCACGAATATTTTATGCTGCATTTCGGTCAGTTAGATCATGA
GGATGAAAATATAATATATGAAAATTATCTCCAAGAAGTATA
Protein Sequence 
>gi|227081012|ref|YP_002809563.1| toxin co-regulated pilus biosynthesis protein T [Vibrio cholerae M66-2] MSIDIKYLSRIDIDREEFFFKDSRLMCKKFDEEREVLTLLEFDTKFRVNLLKKDKVYKYFLVSDANHKLLIANLVTEQQAKDLSFIEKDIMKIASSATAYGASDIHFIREDRICKIKFRVNGTMIDYREILSSEADSLMFVLYNVMATTKETTWNRKLPQDANIILVINEKAYRFRYAHMPLFGEGGKNYHAVVRIIYPSNNFVCTNYQDIGYNEADTDAIARILNTSYGLFIVSGTTGSGKSTSLKKYIELLFFNKYKGKGCFVTVEDPVEYLISGAQQSSIVADNDDKTKNPFADAVRSAMRRDPDVIMIGEIRDKPTVEALSSAVESGHYCLTTIHAGSVVSVLQRLSGLGMKADKIASPGFLAGITSQKLIPELCPSCKVSFVDERYQRAVFSANENGCEACNHSGFKGRLLLLETLVPTVEDLELVASENWVSLYRKYRERRFIKTGKKGLGEGFSIKDKAYYNVLKGKVCHEYFMLHFGQLDHEDENIIYENYLQEV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tcpT mutant is attenuated in mice (Chiang and Mekalanos, 1998).
COG COG2804NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Chiang and Mekalanos, 1998: Chiang SL, Mekalanos JJ. Use of signature-tagged transposon mutagenesis to identify Vibrio cholerae genes critical for colonization. Molecular microbiology. 1998; 27(4); 797-805. [PubMed: 9515705].