Victors

VC2295
Victor ID	2406
Gene Name	VC2295
Sequence Strain (Species/Organism)	Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID	2613091
NCBI Protein GI	15642293
Locus Tag	VC2295
Genbank Accession	AE003852
Protein Accession	NP_231926
Other Database IDs	UniProtKB-ID: NQRA_VIBCH UniRef100: UniRef100_Q9KPS1 UniRef90: UniRef90_Q9KPS1 UniRef50: UniRef50_Q1QX86 UniParc: UPI0000130436 EMBL: AF117331 EMBL: AE003852 EMBL-CDS: AAD29962.1 EMBL-CDS: AAF95439.1 RefSeq_NT: NC_002505.1 GenomeReviews: AE003852_GR KEGG: vch:VC2295 TIGR: VC_2295 HOGENOM: HBG413878 OMA: EYGPILR ProtClustDB: PRK05352
Taxonomy ID	243277
Chromosome No	I
Gene Starting Position	2449431
Gene Ending Position	2450819
Gene Strand (Orientation)	-
Protein Name	Na(+)-translocating NADH-quinone reductase subunit A
Protein pI	7.01
Protein Weight	45678.76
Protein Length	462
Protein Note	uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm
DNA Sequence	>gi\|15640032:2449431-2450819 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome ATTACCCTTCTTTCTCGATCTTGTCTAAGCACTCACGCAGGAGCTGACCGTACTCGTATTTGCCTGGGCA AACGAACGTACACAGTGCTAGATCTTCTTCATCCAGCTCTAAAGCACCTAAGCGAACCGCGCTGTCACTG TCACCAGCACACAGATCACGAAGCAACAAGGTTGGCTCCATATCTAGTGGCATGACCTTCTCATAGTTAC CGATTGGAACCATAGATCGATCACTACCATTAGTGGTTGTGGTCATGTTGTACACTTGGCCCTTGAATAG GTGACCAAGGAAAGAGCGAGTCACAGAGAACTTGTTCTTACCCGGCATCGCCCAACCAAACAGTTCTTTA TCACGTCCTTCACGAAGAACAGAGACCTGTAGGTGGTAACGACCAAGATAAGCGTGTGGTCCAGTGGCTT TCGTACCAGACAGCACAGAGCCAGAGATGATGCGTACTTCGCCAGGCATGATTTCGCTGTCCACCAGTTG CTCTAGTGATGCGCCCATGACAGTGCGAACCAAACGAGGTTTGTTCACCACCGGGCCGGCAAGAGAAACC ACACGCTGGGTGTATAGCTCGCCCGTCAGGAACAGTTGACCTACTGCGATCACGTCCTGATAGTTGATGC TCCACGCCACGTGGTCTGCACTTACTGGATAGAGGAAATGCATGTGAGTGCCAGCTAAGCCTGCAGGATG TGGGCCGTCAAAGACATGTTCTTCAACATTCGGCTGTTGAGAACGTGGCAAGCTGGTGCCTTTTTTACAA ACGTACACTTTGCCAGTTGTCAGTGCGGAAAGCACATCTAGACCAGCAACGAAGGCTTCAGATTGTTCAT TGATCACAACGGTCGGCTCAGCTGCCAACGGATTGGTATCCATAGCAGTGACAAAAATGGCTTCAGAAGT GGAATCAATGGCTGGAACCTTGCTGAACGGACGAGTACGGAAAGCAGTCCAAAGACCAGACTCAACCAGC TGAGTTTTGATCGCATCGCGATTCAAACTGGCTAATTGATTGGCTTCAAACTTGTCGAAGGTCACTTGGT CATCACCCGCCACTTCAATCACTACAGACTGAAGAACGCGCTTTGCACCACGATTGATTTCAACCACTTT ACCGCTGACTGGTGAAGTAAATTTCACACCCGGATTCTTCTTATCTTCAAAAAGAATCTGAGCTTTTTTT ACTTCATCACCTACGCGGACATGCATAGTAGGACGCATGCCAACGTACTCTTCGCCAAGCAAGGCGACTT TTTTGATGGCTTTACCATCACTAATCACCTGGGAAGGAGTTCCTGCGATAGGAAGGTCCAATCCCTTTTT TATTGTAATCATACGCACTTGCACTACTTTTATCGGGAAAAAGATTCTTTCATTGCGCA
Protein Sequence	>gi\|15642293\|ref\|NP_231926.1\| Na(+)-translocating NADH-quinone reductase subunit A [Vibrio cholerae O1 biovar El Tor str. N16961] MRNERIFFPIKVVQVRMITIKKGLDLPIAGTPSQVISDGKAIKKVALLGEEYVGMRPTMHVRVGDEVKKA QILFEDKKNPGVKFTSPVSGKVVEINRGAKRVLQSVVIEVAGDDQVTFDKFEANQLASLNRDAIKTQLVE SGLWTAFRTRPFSKVPAIDSTSEAIFVTAMDTNPLAAEPTVVINEQSEAFVAGLDVLSALTTGKVYVCKK GTSLPRSQQPNVEEHVFDGPHPAGLAGTHMHFLYPVSADHVAWSINYQDVIAVGQLFLTGELYTQRVVSL AGPVVNKPRLVRTVMGASLEQLVDSEIMPGEVRIISGSVLSGTKATGPHAYLGRYHLQVSVLREGRDKEL FGWAMPGKNKFSVTRSFLGHLFKGQVYNMTTTTNGSDRSMVPIGNYEKVMPLDMEPTLLLRDLCAGDSDS AVRLGALELDEEDLALCTFVCPGKYEYGQLLRECLDKIEKEG
Molecule Role	Virulence factor
Molecule Role Annotation	MUTATION: VC2295 mutant is attenuated in mice (Merrell et al., 2002).
COG	COG1726C, under C: Energy production and conversion
References	*Merrell et al., 2002:* Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].


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VC2295