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tolB from Vibrio cholerae O1 biovar El Tor str. N16961

Victor ID 2417
Gene Name tolB from Vibrio cholerae O1 biovar El Tor str. N16961
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2613590
NCBI Protein GI 15641838
Locus Tag VC1836
Protein Accession NP_231470.1
Other Database IDs UniProtKB-ID: TOLB_VIBCH
UniRef100: UniRef100_A5F753
UniRef90: UniRef90_A5F753
UniRef50: UniRef50_Q3IJ16
UniParc: UPI00000C60B3
EMBL: AE003852
EMBL-CDS: AAF94984.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC1836
TIGR: VC_1836
HOGENOM: HBG644919
OMA: RVADYDG
ProtClustDB: PRK04792
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 1977119
Gene Ending Position 1978471
Gene Strand (Orientation) -
Protein Name translocation protein TolB
DNA Sequence 
>gi|15640032:1977119-1978471 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
GTTATAAAAACGGTGACCATGCTGGAGCACGAACGCGCCCATTGGTTGCCGGTAATCTTGCTTTAAAGCG
TCCATCAATGGATACCATCGACAAGACGTTGGCCTTATTGTAGATGGAGCTATAAATCACCATACCACCA
TTCGGCGCAATACTTGGGGACTCATCTAACAAGGTTTTTGTCAGAATCTGCATTGCCCCTGTTTCTAAAT
CCTGCTTCGCGAGATTGAAGCCGGAATCACTACGATTCACCATCACCAAGAATTTTCCATCCGGTGTAAT
TTGGCCACCCAAGTTTTGGCTACCTTGCCAAGTTAAACGCTTGGTTTCACCGCCGGATAAATTTACTTGA
TAAATCTGTGGTTTACCACCCCGATCTGAAGTGAAAATTAAAGATTTACCATCTGGATGCCAGAAAGGTT
CGGTGTTGTTGGAACGGCCACTAGTCACCTCTGTTAAGCGACGTGTAGCCAAGTCCATCGTGTAGACCTG
TAAATTACCAGTTTTTGATAAAACCAGCGCTAGCGTTTTACCATCTGGTGAGAATCTGGGTGCACCATTA
TGACGTGGGAATGACGTCAGCTTCTCTCGCTTCCCACTGTAGATGTTCATCATGTAAATTTCGGCTTGTC
CGTTTTGGAAACTCACGTAAGCCAAAGTCTGACCATCAGGTGACCAAGCAGGTGACATAAGCGGCTGCTT
AGAACGAAGTACAAGACGTTCGTTATAGCCGTCATAATCAGCAATTCTCAGTTGATAAGGATACGGATCC
TTATCATTGACCACAACGTAAGCGATGCGCGTTAAGAAGGCGCCGCGTTCACCGGTCAATTCCTCATAAA
CCAAGTCCGCAATACGGTGGGCATATTCACGCATTCTTGATGCAGGAACGGTCGCCACTTTATTAAACAA
AACATGATCTTTAGATAGCACCAATTGACCATCTTGAGACAGAGCTTTGCTTTGGCCTTGAGTCAGTTGT
CCACGCACAATGTCAACCAGTTGATAACTAATTACATAGCTACCTTCCGCATTTTGCGTGATCGTACCCG
TCAATAATGAATCGACCCCCATAGATGTCCATTTGCCAAAGTTAACCTGCTCTTCGCTATAAGGCGTCTG
TGGCATTTTGCTGGTCGGAACTGGGCTAAATTTACCACTGCGCTGTAAGTCAGAGGCAATCACCGCAGAA
ACGTCTTCAGGCAACTTGGTTGCGCCTTCCCATTTGAAAGGAACTATCGCAATCGGACGTGCAGAATCAA
TACCGTCAGTAATAACTAGCTCCAATGCTGCATTCGCAATATTGGAAAAACCGGTACCGATGAGCATCAA
AACAAAAACTAATCGCTTAAACA
Protein Sequence 
>gi|15641838|ref|NP_231470.1| translocation protein TolB [Vibrio cholerae O1 biovar El Tor str. N16961] MFKRLVFVLMLIGTGFSNIANAALELVITDGIDSARPIAIVPFKWEGATKLPEDVSAVIASDLQRSGKFSPVPTSKMPQTPYSEEQVNFGKWTSMGVDSLLTGTITQNAEGSYVISYQLVDIVRGQLTQGQSKALSQDGQLVLSKDHVLFNKVATVPASRMREYAHRIADLVYEELTGERGAFLTRIAYVVVNDKDPYPYQLRIADYDGYNERLVLRSKQPLMSPAWSPDGQTLAYVSFQNGQAEIYMMNIYSGKREKLTSFPRHNGAPRFSPDGKTLALVLSKTGNLQVYTMDLATRRLTEVTSGRSNNTEPFWHPDGKSLIFTSDRGGKPQIYQVNLSGGETKRLTWQGSQNLGGQITPDGKFLVMVNRSDSGFNLAKQDLETGAMQILTKTLLDESPSIAPNGGMVIYSSIYNKANVLSMVSIDGRFKARLPATNGRVRAPAWSPFL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tolB mutant is attenuated in mice (Merrell et al., 2002).
COG COG0823U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].