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lysA from Vibrio cholerae O395

Victor ID 2357
Gene Name lysA from Vibrio cholerae O395
Sequence Strain (Species/Organism) Vibrio cholerae O395
NCBI Gene ID 5136731
NCBI Protein GI 147674363
Locus Tag VC0395_A2394
Protein Accession YP_001218294.1
Taxonomy ID 345073
Chromosome No 2
Gene Starting Position 2548795
Gene Ending Position 2550048
Gene Strand (Orientation) -
Protein Name diaminopimelate decarboxylase
DNA Sequence 
>gi|147673035:2548795-2550048 Vibrio cholerae O395 chromosome 2, complete sequence
TTTACTCCGGTAATACCGATTCTAACGCCCACAAGCTGCTAAGCTCTTCACGCTGACGCACCAAATAGGT
TTTATTGCCATCAACCATGACTTCAGCCACTCGCGGACGGGTATTGTAATTCGACGACATGGTAAACCCA
TACGCACCAGAAGAGCGCACCGCCAGTAAATCCCCCTCTTGCAACACTAAGTCGCGATCTTTCCCTAGGA
AATCACTGGTTTCACACACCGGGCCAACCAAATCATAAGTTTGGGCTTCGCCTTGGCGCGGACGCAGTGG
AATGATGTCTTGCCACGCTTGGTATAGCGCCGGGCGGATCAAATCGTTCATCGCCGCATCAATGATCGCG
AAGTTTTTGTGCTCAGTGTGTTTGAGAAACTCCACCTTAGTCACCAATACTCCCGCGTTAGCCGCAATCG
CGCGTCCCGGTTCAAAAATCAGCTCTAAATCGCGGTGGCGCTCTAGGCGGTCCAGCAATGCTTTGGCGTA
TTCCGAAGGCTGCGGAGGCAGTTCATCACGATAAACCACCCCTAAACCACCGCCGACATCCAAGTGGCGG
ATATGAATGCCTTCCGCTTTCAGCGAATCAATCAGTGCCAGTAAACGGTCAGTCGCATCAATAAACGGTG
CGAGAGCGGTTAGCTGTGAGCCGATATGGCAGTCAATACCATGTACATCGAGGTTGGGTAAGCTGTGCGC
TAAGCGATATACCTGCGCTGCGCGGTCAAAGGTGATACCAAATTTGTTATCACGTAGACCCGTTGAAATG
TAAGGGTGAGTTTTGGCATCCACATCAGGATTGATGCGCAGTGAAATCGGCGCTTTAACACCAAGCTCGC
CAGCCACTTTATTCAGGCGCTGCAGCTCAGGCTCCGATTCCACGTTAAAGCATTTGATCTTCAATTGCAG
GGCGCGCTTCATCTCAGCTTCGGTTTTACCCACACCAGAGAATACCACCTTGCTTGGGTCACCACCGGCG
GCCAATACACGCTCTAATTCGCCAACGGAGACGATATCAAAACCTGAACCCAAACGAGCTAAAGTATTCA
ATACCCCTAAGTTAGAGTTGGCTTTCACCGCATAACAAATTAGGTGAGGATAATCACCGACTGATTTATC
AAACGCGTGCCAATGGCGCTCAAGTGTCGCTCTTGAGTAAACATAAAGCGGTGTACCGTACTGGTTTGCC
AAATCGGCGAGTGGAACTTGCTCAGCCCACAACTGACCATCTTCCTGATAATTGAAGTAATCCA
Protein Sequence 
>gi|147674363|ref|YP_001218294.1| diaminopimelate decarboxylase [Vibrio cholerae O395] MDYFNYQEDGQLWAEQVPLADLANQYGTPLYVYSRATLERHWHAFDKSVGDYPHLICYAVKANSNLGVLNTLARLGSGFDIVSVGELERVLAAGGDPSKVVFSGVGKTEAEMKRALQLKIKCFNVESEPELQRLNKVAGELGVKAPISLRINPDVDAKTHPYISTGLRDNKFGITFDRAAQVYRLAHSLPNLDVHGIDCHIGSQLTALAPFIDATDRLLALIDSLKAEGIHIRHLDVGGGLGVVYRDELPPQPSEYAKALLDRLERHRDLELIFEPGRAIAANAGVLVTKVEFLKHTEHKNFAIIDAAMNDLIRPALYQAWQDIIPLRPRQGEAQTYDLVGPVCETSDFLGKDRDLVLQEGDLLAVRSSGAYGFTMSSNYNTRPRVAEVMVDGNKTYLVRQREELSSLWALESVLPE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: lysA mutant is attenuated in mice (Merrell et al., 2002).
COG COG0019E, under E: Amino acid transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].