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VC2426

Victor ID 2395
Gene Name VC2426
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2612968
NCBI Protein GI 15642423
Locus Tag VC2426
Genbank Accession HB973679
Protein Accession NP_232056
Other Database IDs UniProtKB-ID: O68839_VIBCH
UniRef100: UniRef100_A5F5L6
UniRef90: UniRef90_A5F5L6
UniRef50: UniRef50_E1SN76
UniParc: UPI00000D4145
EMBL: AF055371
EMBL: AF109904
EMBL: AE003852
EMBL-CDS: AAC63504.1
EMBL-CDS: AAD21032.1
EMBL-CDS: AAF95569.1
RefSeq_NT: NC_002505.1
MEROPS: A24.001
GenomeReviews: AE003852_GR
KEGG: vch:VC2426
TIGR: VC_2426
HOGENOM: HBG710101
OMA: DHQLLPD
ProtClustDB: CLSK874797
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 2600668
Gene Ending Position 2601543
Gene Strand (Orientation) +
Protein Name leader peptidase PilD
Protein pI 7.33
Protein Weight 30647.19
Protein Length 291
Protein Note similar to GP:3025799; identified by sequence similarity; putative
DNA Sequence 
>gi|15640032:2600668-2601543 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
AATGGAACTGTTTTACTTCTACCCTTGGCTGTTTCCGGTGCTCGCCACGCTGTTTGGCTTGATTGTCGGT
AGCTTTCTCAATGTGGTGATCTATCGCTTACCCAAAATCATGGAGCGTGAATGGCGCGCGGAATGTGCGG
CGAGTTTTCCTGAATATGGCATCACGCCACCAGAGGGTAAACTGACCCTCAGTTTGCCGCGTTCCACTTG
CCCACACTGTCAAACGCCGATTCGCGTCATTGATAATATCCCGCTACTGAGTTGGCTAGCGCTGCGCGGT
CAATGCTCACACTGTAAAGCGCCGATCAGCGCTCGCTATCCCTTGATTGAGCTACTCACTGCCCTCATGA
GCTTAGTGATTGCCACTCACTTTCCGTTCGGAGTTTTTGCCGTGGCGCTGCTGTTTTTCAGCTATGTGTT
GATTGCGGCAACCTTCATCGACTTCGATACCCTGTTGTTGCCCGACCAATTAACGCTACCTTTACTGTGG
GGCGGTATTGCACTGGCACTGCTTGGTTTTTCTCCTGTTTCACTCAGTGATGCGGTGATCGGAGCCATGG
CGGGTTATCTCTCGCTGTGGTCGATTTACTGGCTATTTAAACTGCTGACAGGTAAAGAAGGCATGGGTTA
TGGCGATTTCAAATTGCTCGCCGCTCTCGGCGCTTGGCTGGGTTGGCAGCAGTTGCCTGTCATCGTACTG
CTCTCATCGGTGGTTGGGGTGATTTTCGGTTTAATCCAACTGCGCCAGCAGAAAAAAGGTATCGATATGG
CCTTTCCGTTTGGCCCTTATCTCGCCATCGCGGGATGGTTTGCCTTGCTGTGGGGCGATAAGGTAATTGA
TTGGTACTTCACCACTTGGGTAGGACAACCGTTATG
Protein Sequence 
>gi|15642423|ref|NP_232056.1| leader peptidase PilD [Vibrio cholerae O1 biovar El Tor str. N16961]
MELFYFYPWLFPVLATLFGLIVGSFLNVVIYRLPKIMEREWRAECAASFPEYGITPPEGKLTLSLPRSTC
PHCQTPIRVIDNIPLLSWLALRGQCSHCKAPISARYPLIELLTALMSLVIATHFPFGVFAVALLFFSYVL
IAATFIDFDTLLLPDQLTLPLLWGGIALALLGFSPVSLSDAVIGAMAGYLSLWSIYWLFKLLTGKEGMGY
GDFKLLAALGAWLGWQQLPVIVLLSSVVGVIFGLIQLRQQKKGIDMAFPFGPYLAIAGWFALLWGDKVID
WYFTTWVGQPL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC2426 (pilD/vcpD) mutant is attenuated in mice (Marsh and Taylor, 1998).
COG COG1989NOU, under N: Cell motility; O: Posttranslational modification, protein turnover, chaperones; U: Intracellular trafficking, secretion, and vesicular transport
References
Marsh and Taylor, 1998: Marsh JW, Taylor RK. Identification of the Vibrio cholerae type 4 prepilin peptidase required for cholera toxin secretion and pilus formation. Molecular microbiology. 1998; 29(6); 1481-1492. [PubMed: 9781884].