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VC0242

Victor ID 2453
Gene Name VC0242
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2614705
NCBI Protein GI 15640272
Locus Tag VC0242
Genbank Accession AE003852
Protein Accession NP_229899
Other Database IDs UniProtKB-ID: RFBB_VIBCH
UniRef100: UniRef100_Q06951
UniRef90: UniRef90_Q06951
UniRef50: UniRef50_Q06951
UniParc: UPI00001337D5
EMBL: X59554
EMBL: AE003852
EMBL-CDS: CAA42135.1
EMBL-CDS: AAF93418.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC0242
TIGR: VC_0242
HOGENOM: HBG644964
OMA: DGSWFNL
ProtClustDB: CLSK873915
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 247928
Gene Ending Position 249319
Gene Strand (Orientation) +
Protein Name phosphomannomutase
Protein pI 4.95
Protein Weight 49257.5
Protein Length 463
Protein Note similar to GB:X59554 SP:Q06951 PID:581822; identified by sequence similarity; putative
DNA Sequence 
>gi|15640032:247928-249319 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
AGTGAAAGAGTTAACTTGTTTTAAAGCCTACGATATTCGCGGACAATTAGGGAGTGAGCTTGATAATGAA
ATTGCCTACAGAATTGGTCGCTCGTATGGGCAGTTTTTAAAAAGCGAAAATGACGCAGATAAAACAGTTG
TGGTAGGTGGTGATGTTCGTTTAACCAGCGAAGCGCTTAAACAAGCACTAGCTAATGGCTTAATGGATGC
AGGTATTAACGTTATTGATATTGGCGTTACTGGTACCGAAGAGATCTATTTTGCAACCTTCTACCTTGGT
GTTGATGGTGGTATTGAAGTTACCGCAAGTCATAACCCAATGGATTACAATGGTATGAAGCTGGTTCGTG
AAGGTTCAAAACCCATTAGTGGTGATACTGGTTTACGAGAAATTCAAGCTTTGGCTGAAAAGAATGAATT
TATGGACGTTGAAGTTAAAGGTAACTACAAAAAGGTTTCTTTACTTCCAGAATATGTAGATCACTTAATA
TCTTATATTACACCCGCGAAAATTAAACCAATGAAGTTGGTCATCAATTCAGGTAACGGAGCTGCAGGCC
ACGTGATTGATGAGTTGGAAAAACGATTTATTGAATTGAGTATCCCGCTAGAAATTATCAAAGTGCATCA
TGAAGAAGATGGTAACTTCCCGAATGGTATTCCTAACCCATTGTTACCTGAATGCCGTGCTGATACCGCA
AACGCAGTAAAGGAGCACAAGGCTGATATGGGCATTGCCTTTGATGGTGACTTTGATCGCTGCTTTTTGT
TTGATGAAAATGGCGATTTTATTGAAGGTTACTACATCGTAGGTTTATTGGCAGAAGCGTTTTTACAGAA
AGAGCAAGGTGCCAAAATTATTCATGATCCACGCTTAAGCTGGAACACCATTGATGTGGTGACTAAGTCG
GGTGGCGTGCCTGTAATGTCTAAAACAGGGCATGCATTTATAAAAGAGCGTATGCGCAAAGAAGATGCTA
TCTACGGTGGTGAAATGAGTGCCCATCACTACTTCCGTGATTTCGGTTACTGTGATTCGGGGATGATTCC
GTGGCTTCTGATTACAGAGTTACTTTCCTTAGCCCCGGATATTAGCTTATCTAAGCTGATATCTGCAAAA
AGATTTTTGTTTCCATGTAGCGGTGAAATTAATTTTAAGGTCAAGCAGGCAAAGCTAATAATGGAGCAAG
TTTATTTACATTATTACGAGAATTCTATACATTTCTCTGCCATTGATGGTATCTCTCTTGAATTTGAAGG
ATGGCGTTTTAATCTTAGAGATTCAAATACTGAGCCCTTATTAAGATTGAATGTGGAATCTAAACAAAAT
ATCGCGTTGATGAATGATAAAGTTGAAGAGCTTACTAAATTAATTAAGAAATTGGATATTTA
Protein Sequence 
>gi|15640272|ref|NP_229899.1| phosphomannomutase [Vibrio cholerae O1 biovar El Tor str. N16961]
MKELTCFKAYDIRGQLGSELDNEIAYRIGRSYGQFLKSENDADKTVVVGGDVRLTSEALKQALANGLMDA
GINVIDIGVTGTEEIYFATFYLGVDGGIEVTASHNPMDYNGMKLVREGSKPISGDTGLREIQALAEKNEF
MDVEVKGNYKKVSLLPEYVDHLISYITPAKIKPMKLVINSGNGAAGHVIDELEKRFIELSIPLEIIKVHH
EEDGNFPNGIPNPLLPECRADTANAVKEHKADMGIAFDGDFDRCFLFDENGDFIEGYYIVGLLAEAFLQK
EQGAKIIHDPRLSWNTIDVVTKSGGVPVMSKTGHAFIKERMRKEDAIYGGEMSAHHYFRDFGYCDSGMIP
WLLITELLSLAPDISLSKLISAKRFLFPCSGEINFKVKQAKLIMEQVYLHYYENSIHFSAIDGISLEFEG
WRFNLRDSNTEPLLRLNVESKQNIALMNDKVEELTKLIKKLDI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC0242 mutant is attenuated in mice (Merrell et al., 2002).
COG COG1109G, under G: Carbohydrate transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].