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acfA from Vibrio cholerae O395

Victor ID 2370
Gene Name acfA from Vibrio cholerae O395
Sequence Strain (Species/Organism) Vibrio cholerae O395
NCBI Gene ID 5137546
NCBI Protein GI 147674631
Locus Tag VC0395_A0368
Protein Accession YP_001216324.1
Taxonomy ID 345073
Chromosome No 2
Gene Starting Position 396298
Gene Ending Position 396945
Gene Strand (Orientation) -
Protein Name accessory colonization factor AcfA
DNA Sequence 
>gi|147673035:396298-396945 Vibrio cholerae O395 chromosome 2, complete sequence
ACTAGAAGTAGTACTTTGAATTTAAACTTATAGAAAGCACATCATTGTACTTATCGAACTGATATCTTAA
CTCTGTTCCAACGCTAAGCTCTGGAATTAAATTATAATCCAACCCTAACGAAAATAGTGCACCAAAGCGA
TTCTTTTTAAGACCTGTTTCTAATAGAGCTTTTCTAATCTCTATATCATCATTTAGGAGTAATTCTAGCT
CTTCATATTTTCCAGAATATGCTTCATATTGTGTATGTGTCACACCAACTTTTATATTTGTTTTCAATTG
CTGATGAATGGGGTATGAGTAAACTGAGATTAATGCAAGTTGTTTAGCTTCAATCTCAGAGCTCCATTCG
TGCTCTTTTCTATATTGTTGATTATTTAAAGATTCAATTCCTATAAACTTACTGTATTGATCTTCTAATT
TATAACTTGAATAGTTGATTTCAAAAGAAAAATTATCATTAAATTTATAACCAATTAGTCCACCTAAAAA
CATATCTTCCATATTGGGGTTTAGGCTAACAGCGTCACTTTGATAGTTCGTCTCAAAGCTATGATTTGCT
GTTCCAATTCCAAGTTCAAGACCAATATACGGTGCTGCATTTGCTGATAAAGTCGTAAACAAAAAAATTG
CTGATAAAGTTTTTTGCA
Protein Sequence 
>gi|147674631|ref|YP_001216324.1| accessory colonization factor AcfA [Vibrio cholerae O395] MQKTLSAIFLFTTLSANAAPYIGLELGIGTANHSFETNYQSDAVSLNPNMEDMFLGGLIGYKFNDNFSFEINYSSYKLEDQYSKFIGIESLNNQQYRKEHEWSSEIEAKQLALISVYSYPIHQQLKTNIKVGVTHTQYEAYSGKYEELELLLNDDIEIRKALLETGLKKNRFGALFSLGLDYNLIPELSVGTELRYQFDKYNDVLSISLNSKYYF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: acfA mutant had a defect in colonization of mice, and had a ten-fold increase in the 50% lethal dose in mice (Peterson and Mekalanos, 1988).
References
Peterson and Mekalanos, 1988: Peterson KM, Mekalanos JJ. Characterization of the Vibrio cholerae ToxR regulon: identification of novel genes involved in intestinal colonization. Infection and immunity. 1988; 56(11); 2822-2829. [PubMed: 2902009].