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VC0259

Victor ID 2464
Gene Name VC0259
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2615261
NCBI Protein GI 15640288
Locus Tag VC0259
Genbank Accession AE003852
Protein Accession NP_229915
Other Database IDs UniProtKB-ID: Q07023_VIBCH
UniRef100: UniRef100_C3M3Q4
UniRef90: UniRef90_C3M3Q4
UniRef50: UniRef50_C3M3Q4
UniParc: UPI00000DA178
EMBL: AE003852
EMBL: X59554
EMBL-CDS: AAF93434.1
EMBL-CDS: CAA42151.1
RefSeq_NT: NC_002505.1
GenomeReviews: AE003852_GR
KEGG: vch:VC0259
TIGR: VC_0259
HOGENOM: HBG726846
OMA: VASSPNY
ProtClustDB: CLSK793547
Taxonomy ID 243277
Chromosome No I
Gene Starting Position 264253
Gene Ending Position 265485
Gene Strand (Orientation) -
Protein Name lipopolysaccharide biosynthesis protein RfbV
Protein pI 9.2
Protein Weight 44356.75
Protein Length 410
Protein Note similar to GB:X59554 PID:48400 PID:1929424; identified by sequence similarity; putative
DNA Sequence 
>gi|15640032:264253-265485 Vibrio cholerae O1 biovar El Tor str. N16961 chromosome I, complete genome
TTCAACAGACATTTCCGAAGAGTTCACTATACAGTTTAGTATAGCTTTGTGCATAGCGATGTGCTGTGAA
TTCCTGTTCAAAACGTTTGCGAGCATTAATACCTAATTTTTCACAAAGTTTTGTATCATGTTCTATTTTT
AACATTGCATCGGAAAAGCTTTGACTGTCAGCTGGCGGAACAACTAACCCTGTTTCGCCATTGATGTTCA
CATAAGATGAACCTGTGCCAATATCACTACTAATAATGGCTTTACAGTACATTTGTGCTTCGATAAGTGA
TATACCAAAAGCTTCTGAGCGTAGGTGAGATGGGAAAACAAAAGCTTTAGAAAGTAAATGTAATATGACT
TTGTCTTCCTCAGAAATGAATCCTACTAGCTTAACGTTTTCAAGATTGTGTTTGGCAATATAAGACTCTA
GTTTTACTCTTTCCGGACCGTCACCAGCAATTATAACAGGTAGCTGGTTGATTTTTGCTGCTTCAAGTAA
GAAATCTAGACCCTTGTAGTACCGTAATACGCCAACAAATAAGAAAAAACCTTCCCCTACTTTTTCTCGC
CATTTATTAATATTATCGTTTGATGGGATAGGATAAGTATTCTCATCAACGGCAAGTGGAATTATTTTTA
CCTTATTTTTATGCCTTAACAAATTCTCGCTTGTGTGTGCATATTGTGGTGATGTTGCCACAAGGATATT
TGCTTGATTTAAAAAATGACTCTCAAGTGGTTGATATAATTTCTTTAAGCACTTTTGACGAATAATATCG
GAATGATACGTTACAATACTTGGATTCGATGAGCCAAATAAAGAGAGAAAGTCTCCGGTTGGCCATGGAT
AATGGTAATGGATTATGTCAGCCCATTTTGAAAGTTTCTTGAATTGTCTAATTAGCTTCCACGAGAATCC
ATTTGAAGAGATTTCAATCGATTTTTTTACTGAGATTATTTCTGTTCCTTCACAATAATAAGAAGAAGTT
TGATTATCAGATAATGTAAGTATTTTAGTTTCTATTCCTAACGGTTTTGTTCCCGATGCTATAAATCGAA
TAACTTGCTCAACACCGCCTTTTGTTTCAGGATAACAGGTTCTATATACATGCAATACTTTCATTTTATT
CTCATTTTTGTGGCGAATAACCCGTAGGTGCATCAAGTAAAATTCGCTTAATACATTCAACATCAAAGTT
ATGACAGCATACATCAAGTTCCGTGAGTAGGTCTTCCATGGCA
Protein Sequence 
>gi|15640288|ref|NP_229915.1| lipopolysaccharide biosynthesis protein RfbV [Vibrio cholerae O1 biovar El Tor str. N16961]
MPWKTYSRNLMYAVITLMLNVLSEFYLMHLRVIRHKNENKMKVLHVYRTCYPETKGGVEQVIRFIASGTK
PLGIETKILTLSDNQTSSYYCEGTEIISVKKSIEISSNGFSWKLIRQFKKLSKWADIIHYHYPWPTGDFL
SLFGSSNPSIVTYHSDIIRQKCLKKLYQPLESHFLNQANILVATSPQYAHTSENLLRHKNKVKIIPLAVD
ENTYPIPSNDNINKWREKVGEGFFLFVGVLRYYKGLDFLLEAAKINQLPVIIAGDGPERVKLESYIAKHN
LENVKLVGFISEEDKVILHLLSKAFVFPSHLRSEAFGISLIEAQMYCKAIISSDIGTGSSYVNINGETGL
VVPPADSQSFSDAMLKIEHDTKLCEKLGINARKRFEQEFTAHRYAQSYTKLYSELFGNVC
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VC0259 mutant is attenuated in mice (Merrell et al., 2002).
COG COG0438M, under M: Cell wall/membrane/envelope biogenesis
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].