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aceF from Vibrio cholerae M66-2

Victor ID 3879
Gene Name aceF from Vibrio cholerae M66-2
Sequence Strain (Species/Organism) Vibrio cholerae M66-2
NCBI Gene ID 7773595
NCBI Protein GI 227082534
Locus Tag VCM66_2336
Protein Accession YP_002811085.1
Other Database IDs UniProtKB-ID: C3LQV6_VIBCM
UniRef100: UniRef100_A5F5M0
UniRef90: UniRef90_A5F5M0
UniRef50: UniRef50_P06959
UniParc: UPI0000ED83F5
EMBL: CP001233
EMBL-CDS: ACP06634.1
RefSeq_NT: NC_012578.1
GenomeReviews: CP001233_GR
KEGG: vcm:VCM66_2336
OMA: MEIPAPK
ProtClustDB: PRK11854
Taxonomy ID 579112
Chromosome No I
Gene Starting Position 2520016
Gene Ending Position 2521929
Gene Strand (Orientation) -
Protein Name pyruvate dehydrogenase, E2 component, dihydrolipoamide acetyltransferase
DNA Sequence 
>gi|227080237:2520016-2521929 Vibrio cholerae M66-2 chromosome I, complete genome
CTTACAGTACCAGACGACGGATGTCGCTTAGACACTCGTTCAGGTAAGTAATGAAGCGTGCACCTTCTGC
ACCGTCGATCACGCGGTGATCGTAAGACAGTGACAGTGGCAGTTGCAGACGTGGCGCGAACTCTTTGCCG
TTCCACACTGGCTTCATCTCAGACTTAGACACACCCAAAATAGCCACTTCAGGTGCGTTAACGATTGGGG
TAAACGCTGTACCGCCAATACCGCCTAGGCTAGAGATAGTGAAACAGCCACCTTGCATGTCAGCGGCAGT
CAGCTTACCGCCACGGGCTTTCTTCGAGACTTCAGCCAGCTCTTTTGACAGCTCGTAGATGCCTTTCTTG
TTCACATCTTTAAACACAGGAACCACCAGACCATTTGGTGTATCCACTGCAATACCGATGTTCACGTATT
TCTTCAGGATCAAGCTTTCGCCATCGTCAGACAGAGAAGAGTTGAACGCAGGGAAAGCTTCCAGCGCTTT
CGCAGCGGCTTTCATGATGAACACCAGCGGAGTGATCTTCATGCCAGTGTCGCGCTTCGCTTCCATCGCG
TTTTGCTCTTGACGGAATTTCTCTAGCTCAGTGATGTCTGCATTGTCCCATTGGGTCACGTGCGGGATCA
TCACCCAGTTACGGTGCAGGTTAGCACCCGAGATTTTCTTGATGCGAGACAGTGGTTGCACTTCGGTATC
ACCGAACTTGCTGAAGTCCACTTTTGGCCAAGGCAGTAAGCCCAGCGCTGCGCCATCACCTTTACCTGAA
GCCGCCGCTTGCGCGCCAGATTCCAGACGTTTCAGCGCTTCTTTCACGTAGTTCTGTACGTCTTCTTTCA
GGATACGGTTCTTGCGGCCAGAGCCTTTGACTTTGGCTAGGTTAACACCAAATTCACGAGCCAGACGACG
CACGACTGGAGAAGCGTGTGAGTACTCATGGTTTTCTTGGAATTCACCACTTGTTGCAGGTGCAGCCGCC
GCAGGAGCTGCTGCTTGAGCAGGCGCTGCCGCAGGTGCTGGTGCTGGTGCTGCTTGAACTGGTGCCGCGA
CTGGCGCTGCGCCAGCAACTTCAAACACCATGATCAGCGAACCTGTTTTCACTTTATCGCCTGCAGCCAC
TTTGATCTCTTTGAGAGTTCCAGCAAAAGGTGCTGGTACTTCCATAGAAGCCTTATCGCCTTCTACGGTG
ATCAGAGATTGCTCTTCGCTGATGCTGTCGCCCACGTTAACCATGATTTCCGTTACGGTCACTTCGTCAC
CGCCGATATCAGGTACTTGAACTTCTTTCAGTGCTGCAACAGCTGGAGCAGCAGCTGCCGCTGGTGCCGC
AGCTTGAACTGGTGCTGCAACTGGCGCAGCACCGGCTACTTCAAACACCATGATCAGTGAACCTGTTGAT
ACTTTGTCGCCCGCAGCGATTTTGATCTCTTTAACCGTACCAGCGAAAGGTGCAGGTACTTCCATTGACG
CTTTGTCGCCTTCAACGGTGATCAGAGATTGCTCTTCCGCAACCACATCGCCCACTTTGACCATGATTTC
AGTCACTTCAACTTCATCACCGCCAATGTCTGGTACTTGCACTTCTTTCAGTGCAGCGGCCGCTGGAGCC
GCAGCAACTGGTGCTGCCGCTTGAGGCGCAGGAGCTGGTGCTGCCGCTGCTGCACCTTCCGCTTCAAAGA
CCATGATCAGAGAGCCAGTAGACACTTTGTCACCTGCCACTACTTTGATCTCTTTAACGATACCCGCTTG
AGACGCAGGAACTTCCATAGAAGCTTTGTCGCCTTCAACCGTGATCAGAGATTGCTCTTCAGCCACTTTG
TCGCCGACTTTGACGAGAATCTCAGTGACTTCAACCTCATCCGCACCGATGTCAGGTACATAAATTTCGA
TTGCCATTACTTTTCCTACCTTCA
Protein Sequence 
>gi|227082534|ref|YP_002811085.1| dihydrolipoamide acetyltransferase [Vibrio cholerae M66-2] MKVGKVMAIEIYVPDIGADEVEVTEILVKVGDKVAEEQSLITVEGDKASMEVPASQAGIVKEIKVVAGDKVSTGSLIMVFEAEGAAAAAPAPAPQAAAPVAAAPAAAALKEVQVPDIGGDEVEVTEIMVKVGDVVAEEQSLITVEGDKASMEVPAPFAGTVKEIKIAAGDKVSTGSLIMVFEVAGAAPVAAPVQAAAPAAAAAPAVAALKEVQVPDIGGDEVTVTEIMVNVGDSISEEQSLITVEGDKASMEVPAPFAGTLKEIKVAAGDKVKTGSLIMVFEVAGAAPVAAPVQAAPAPAPAAAPAQAAAPAAAAPATSGEFQENHEYSHASPVVRRLAREFGVNLAKVKGSGRKNRILKEDVQNYVKEALKRLESGAQAAASGKGDGAALGLLPWPKVDFSKFGDTEVQPLSRIKKISGANLHRNWVMIPHVTQWDNADITELEKFRQEQNAMEAKRDTGMKITPLVFIMKAAAKALEAFPAFNSSLSDDGESLILKKYVNIGIAVDTPNGLVVPVFKDVNKKGIYELSKELAEVSKKARGGKLTAADMQGGCFTISSLGGIGGTAFTPIVNAPEVAILGVSKSEMKPVWNGKEFAPRLQLPLSLSYDHRVIDGAEGARFITYLNECLSDIRRLVL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: aceF mutant is attenuated in mice (Merrell et al., 2002).
COG COG0508C, under C: Energy production and conversion
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].