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VCA0896

Victor ID 2387
Gene Name VCA0896
Sequence Strain (Species/Organism) Vibrio cholerae O1 biovar El Tor str. N16961
NCBI Gene ID 2612623
NCBI Protein GI 15601650
Locus Tag VCA0896
Genbank Accession AE003853
Protein Accession NP_233281
Other Database IDs UniProtKB-ID: Q9KL52_VIBCH
UniRef100: UniRef100_A5F0Q7
UniRef90: UniRef90_A5F0Q7
UniRef50: UniRef50_P77809
UniParc: UPI00000C36B1
EMBL: AE003853
EMBL-CDS: AAF96793.1
RefSeq_NT: NC_002506.1
HSSP: P11413
GenomeReviews: AE003853_GR
KEGG: vch:VCA0896
TIGR: VC_A0896
HOGENOM: HBG322449
OMA: VFIIMGA
ProtClustDB: PRK05722
Taxonomy ID 243277
Chromosome No II
Gene Starting Position 850220
Gene Ending Position 851725
Gene Strand (Orientation) +
Protein Name glucose-6-phosphate 1-dehydrogenase
Protein pI 5.76
Protein Weight 54487.62
Protein Length 501
Protein Note catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate
DNA Sequence 
>gi|15600771:850220-851725 Vibrio cholerae O1 biovar eltor str. N16961 chromosome II, complete sequence
GATGATGGTAATACCTGAAAACAGCAGCATCGTAATTTTCGGTGCTTCGGGAGATTTGACGTACCGTAAG
CTTATTCCTGCGTTGTATCACCTCTATGCCAGTCAGCAACTGCCTAAATCGTTTGCGATTTTAGGTGTGA
GCCGTACCGAGTACAGTGACGAGTCTTACCGCGAGAAGCTAAAGCGCTCACTGCAAGAGCTGGAAAAAAC
AGAACCTGCCGCTCTCGAAGCCTTCATGCAGCATGTGCATTATCAAGCGCTGAACACCTCAGAAGTAGCT
GATTATCAGCACTTAGCGACCCGCCTTGATACACTGGCTAACGATTATCAGTTTGAGCAGCGTAATACGC
TGTTTTATCTCGCAACTCCACCAAGCTTGTATGGCGTGATCCCAGCTTGCCTTGCGGCACATGGCCTCAA
CGATGAGAGCCAAGGCTGGAAGCGTCTGATCATCGAAAAACCTTTTGGTTACGATCTGCAATCTGCACAA
GATCTGGATGTGGAAATCCACCACCACTTCAAAGAGCATCAGATCTACCGTATCGACCACTACCTTGGTA
AAGAAACCGTGCAAAACCTGCTGGTGTTCCGCTTTGCCAACGGCATGTTTGAGCCACTGTGGAACCGTAA
CTTTATTGATTACGTGGAAATCACAGGCGCAGAATTCCTAGGTGTGGAAGAGCGCGGCGGTTATTACGAT
GGTTCTGGCGCGGTGCGCGATATGTTCCAAAACCACCTGCTGCAAGTGCTGGCTATGGTGGGCATGGAGC
CGCCTGCGGCGATCAACGCGGATTCCATTCGTAACGAAGTGAACAAGGTACTGCAAAGCCTACAACCGCT
TTCTGAATCTGATCTGCGCAACAATCTGGTGCTCGGTCAATACACCGAATCGGAAGTGCGTGGGCAATTT
TTACCCAGCTACCGTAATGAGCCGGGCGTGGCGGCGGATTCACGCACCGAAACTTACGTCGCGCTAAAAA
TGTTCATCAATAACTGGCGTTGGAATGGTGTGCCATTCTATGTGCGCAGCGGTAAACGTTTACCAACGCG
TGTCACCGAAGTGGTCATTCACTTCAAACGTACACCGCATCCTGTCTTTGGGCAAAATGCGCCAGAGAAC
AAGCTGATCATCCGTATTCAGCCTGATGAAGGCATTCTGATGAGCTTCGGCTTGAAAGAGCCCGGCGCAG
GTTTCAAAGCCAAAGAAGTGTCGATGAATTTCCACTACGCCTCACTTGAGCAGATCAAAATGCTGACCGC
TTATGAGCGTTTGCTGCTGGATGCACTCAATGGTGACGCGACACTGTTTGCCCGTACTGATGCTGTAGAA
GCTTGTTGGAAGTTTGTGCAGCCGATCCTCGATTTCAAACAAGATCCGCAATCGCTGTATGGCTACGCCT
GTGGCACTTGGGGCCCGAAAGAGTCGGATGACTTGCTGCGCCGTGACGGCCGTGAGTGGCGCTTCCCTTG
TAAAAACCTCACTAACACGGATTACTGCGAATTATG
Protein Sequence 
>gi|15601650|ref|NP_233281.1| glucose-6-phosphate 1-dehydrogenase [Vibrio cholerae O1 biovar eltor str. N16961]
MMVIPENSSIVIFGASGDLTYRKLIPALYHLYASQQLPKSFAILGVSRTEYSDESYREKLKRSLQELEKT
EPAALEAFMQHVHYQALNTSEVADYQHLATRLDTLANDYQFEQRNTLFYLATPPSLYGVIPACLAAHGLN
DESQGWKRLIIEKPFGYDLQSAQDLDVEIHHHFKEHQIYRIDHYLGKETVQNLLVFRFANGMFEPLWNRN
FIDYVEITGAEFLGVEERGGYYDGSGAVRDMFQNHLLQVLAMVGMEPPAAINADSIRNEVNKVLQSLQPL
SESDLRNNLVLGQYTESEVRGQFLPSYRNEPGVAADSRTETYVALKMFINNWRWNGVPFYVRSGKRLPTR
VTEVVIHFKRTPHPVFGQNAPENKLIIRIQPDEGILMSFGLKEPGAGFKAKEVSMNFHYASLEQIKMLTA
YERLLLDALNGDATLFARTDAVEACWKFVQPILDFKQDPQSLYGYACGTWGPKESDDLLRRDGREWRFPC
KNLTNTDYCEL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: VCA0896 mutant is attenuated in mice (Merrell et al., 2002).
COG COG0364G, under G: Carbohydrate transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].