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purF from Vibrio cholerae O395

Victor ID 2353
Gene Name purF from Vibrio cholerae O395
Sequence Strain (Species/Organism) Vibrio cholerae O395
NCBI Gene ID 5136658
NCBI Protein GI 147673131
Locus Tag VC0395_A0525
Protein Accession YP_001216476.1
Taxonomy ID 345073
Chromosome No 2
Gene Starting Position 565088
Gene Ending Position 566602
Gene Strand (Orientation) +
Protein Name amidophosphoribosyltransferase
DNA Sequence 
>gi|147673035:565088-566602 Vibrio cholerae O395 chromosome 2, complete sequence
CATGTGTGGTATTGTTGGAATCGTGGGTACAACGCCTGTAAACCAGTCAATTTATGACGCTTTGACGGTC
TTGCAGCATCGTGGCCAAGATGCCGCGGGTATTTGTACCATAGAAAGCAATCGTTTTCGTCTGCGTAAGG
CAAACGGATTAGTCAGGGATGTCTTTGAAGCGAAACACATGCAACGCCTGCAAGGCAACGTCGGGATCGG
CCATGTGCGTTACCCCACCGCAGGTAGCTCTAGCGCCTCAGAAGCTCAACCTTTCTATGTCAACTCTCCT
TTCGGTATCACACTTGCTCACAACGGTAATCTGACCAACGCGAACCAAGTGCGTCAAAAGCTGTTTGAAA
AAGACCGTCGTCATGTGAATACCACTTCGGATTCAGAGGTGTTGCTCAATGTCCTGGCTCATGAAATTGA
TACCGTAAAGGGCAATGTCACCGCCGAAGATGTGTTCCGTGCAATCAGCAATGTTCACCGTACCATTCGT
GGTGCTTATGCGGTGGCGGCGATGATCATTGGTCACGGTATGATTGCGTTTCGTGACCCACACGGTATTC
GCCCATTGTGTCTCGGTAAGCGTGAAGTTAATGGTCAGCTCGAATATATGGTCGCCTCCGAATCGGTCGC
ACTGGATGCGGTTGGGTTCGACTTCGTGCGAGATGTCGCGCCCGGTGAAGCGATTTATGCCACTTTCGAC
GGTGAGCTCTACACCAAACAGTGTGCCGATAATCCAGCACTCAACCCATGCATCTTTGAATTTGTCTACT
TTGCGCGCCCAGATTCGTTTATCGACAAGATTTCCGTTTACAGCGCTCGTGTAGAGATGGGTAAGCGTTT
AGGTGAGCGCATCAAAAACGATTACAGCGATCTCGATATCGATGTAGTCATCCCGATTCCTGAAACCTCT
TGTGATATCGCCCTACAAATTGCACAGGCGATTGATAAACCATATCGCCAAGGCTTTGTTAAAAACCGCT
ATGTTGGTCGAACCTTTATCATGCCGGGTCAGCAGCAACGTAAGAAATCGGTACGCCGCAAACTCAATGC
GATTCGCTCAGAGTTTAAAGATAAAAACGTACTACTGGTGGATGATTCTATCGTGCGTGGCACTACCTCA
GAGCAGATCATTGAGATGGCTCGTGATTCTGGGGCGAAGAAAGTCTACATCGTCTCTGCTGCCCCTGAGA
TTCGCTTCCCGAACGTGTATGGTATTGATATGCCAAGTGCCAATGAGCTGATTGCTCATGGTCGTGATAA
CGATGCTATCTGTAAGCAGATTGGTGCTGATGCCTTGATATTCCAAACTTTAGAGGATTTGGTGGAAGCG
GTTCGCTGTGGCAACCCTGATATCGTCAAGTTTGAAGCTTCGGTCTTTAATGGCGAATACGTGACGGGTG
ACATCGATCAGCAGTACTTAGATTTTCTCGAGTCAATGCGCAGTGATGACGCGAAAGTGCAGCGTGAAAT
TCAACAAGATCTGGCTAACCTTGAGCTGCATAACGAAGGTGCTTA
Protein Sequence 
>gi|147673131|ref|YP_001216476.1| amidophosphoribosyltransferase [Vibrio cholerae O395] MCGIVGIVGTTPVNQSIYDALTVLQHRGQDAAGICTIESNRFRLRKANGLVRDVFEAKHMQRLQGNVGIGHVRYPTAGSSSASEAQPFYVNSPFGITLAHNGNLTNANQVRQKLFEKDRRHVNTTSDSEVLLNVLAHEIDTVKGNVTAEDVFRAISNVHRTIRGAYAVAAMIIGHGMIAFRDPHGIRPLCLGKREVNGQLEYMVASESVALDAVGFDFVRDVAPGEAIYATFDGELYTKQCADNPALNPCIFEFVYFARPDSFIDKISVYSARVEMGKRLGERIKNDYSDLDIDVVIPIPETSCDIALQIAQAIDKPYRQGFVKNRYVGRTFIMPGQQQRKKSVRRKLNAIRSEFKDKNVLLVDDSIVRGTTSEQIIEMARDSGAKKVYIVSAAPEIRFPNVYGIDMPSANELIAHGRDNDAICKQIGADALIFQTLEDLVEAVRCGNPDIVKFEASVFNGEYVTGDIDQQYLDFLESMRSDDAKVQREIQQDLANLELHNEGA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: purF mutant is attenuated in mice (Merrell et al., 2002).
COG COG0034F, under F: Nucleotide transport and metabolism
References
Merrell et al., 2002: Merrell DS, Hava DL, Camilli A. Identification of novel factors involved in colonization and acid tolerance of Vibrio cholerae. Molecular microbiology. 2002; 43(6); 1471-1491. [PubMed: 11952899].