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ugpB from Brucella suis 1330

Victor ID 999
Gene Name ugpB from Brucella suis 1330
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1165097
NCBI Protein GI 23500399
Locus Tag BRA0655
Protein Accession NP_699839.1
Other Database IDs UniProtKB-ID: UGPB_BRUSU
UniRef100: UniRef100_Q8FW10
UniRef90: UniRef90_Q2YKR5
UniRef50: UniRef50_Q2YKR5
UniParc: UPI00000DD9F7
EMBL: AE014292
EMBL-CDS: AAN33844.1
RefSeq_NT: NC_004311.2
GenomeReviews: AE014292_GR
KEGG: bms:BRA0655
NMPDR: fig|204722.1.peg.2748
TIGR: BRA0655
HOGENOM: HBG313575
OMA: ALWIAND
ProtClustDB: CLSK881850
BioCyc: BSUI204722:BR_A0655-MONOMER
Taxonomy ID 204722
Chromosome No II
Gene Starting Position 636566
Gene Ending Position 637867
Gene Strand (Orientation) +
Protein Name glycerol-3-phosphate ABC transporter, periplasmic glycerol-3-phosphate-binding protein
DNA Sequence 
>gi|56968493:636566-637867 Brucella suis 1330 chromosome II, complete genome
CATGTTCACCCGTCTGATCACGACTTCCGCGCTCACGGGAGCTATCGCGCTCACCATCGGTTCTCAGGCT
TTTGCCCAGACGGAACTGGCATGGTGGCACGGCATGACCGGCGCCAACAACGAAATGGTCAATGAGCTCT
CCAAGGAGTTCAACGAAAGCCAGAGCGAATACAAGATCGTTCCGGTTTACAAGGGCAACTATCCTGAAAC
GTTGAACGCGGGCATCGCCGCATTCCGTTCCAAGCAGCCGCCAGCAATCCTTCAGGTTTTCGACGCTGGC
AGCGGCGTGATGATGGCAGCCGAAGGCGCCATAGTTCCGGCTGCCGAAGTGCTCGAAAAGGGTGGCTACA
AGTTCGACAAGTCGCAATATCTGCCGGGTATCGTGGCTTATTATTCCAAGCCGGACGGCACCATGTTGTC
CTTCCCCTACAATTCCTCTTCGCCAATCCTCTATTACAACAAGGACGCCTTCAAGAAGGCCGGCCTTGAT
GAAAACAAGCCGCCGAAGACCTGGCCGGAAGTTTTTGAAGCCGCCAAAAAGATCAAGGCAAGCGGCGCAT
CGCCTTGTGGTTTCACCTCCACCTGGCTGACCTGGATCCAGACCGAAAACTTCGCCGCCTGGAACAATGT
GCCCTATGGCACGAATGAAAATGGCCTTGCCGGGACCGACGTGAAGCTCGAAATCAATTCGCCGCTTTAT
GTCGAGCACTTCCAGGCTATCGCCGATCTCGCCAAGGATGGCACGTTCCGTTATGGCGGCCGCACGTCCG
AGGCAAAGCAGCTCTTCACCTCCGGCGAATGCGCCATGCTGACGGAATCCTCCGGCGGCCTGGGCGATGT
CGTGAAGTCGGGCATCAATTACGGCATCGGCCAGTTGCCTTATTATGAAGGCCATGGCCCGCAGAACACA
ATTCCGGGCGGCGCTTCGCTCTGGGTATTCGCCGGCCTCAGCGACGACCAGTACAAAGGCATCGCGGAAT
TCTTCAATTTCCTCTCGCAGACCAAGATTCAGGTCAAGCTGCATGAAAAATCCGGCTATCTGCCGGTGAC
GCTTGCAGCCTATGAGGAAACCAAGAAGTCGGATTTCTATGAAAAGAATCCGGGCCGCGAAACGCCGATC
CTGCAAATGATGGGCAAGGAGCCGACGGAAAATTCCAAGGGTGTGCGCCTCGTCAATCTGCCGCAGGTTC
GCGACATTCTGAATGAAGAGTTTGAGGCCATGCTGGGCGGCAAACAGGACGCGAAGACCGCACTCGACAA
CGCCGTCAAGCGCGGCAACGCAGCAATCGCCGCAGCTCAATA
Protein Sequence 
>gi|23500399|ref|NP_699839.1| glycerol-3-phosphate ABC transporter periplasmic glycerol-3-phosphate-binding protein [Brucella suis 1330] MFTRLITTSALTGAIALTIGSQAFAQTELAWWHGMTGANNEMVNELSKEFNESQSEYKIVPVYKGNYPETLNAGIAAFRSKQPPAILQVFDAGSGVMMAAEGAIVPAAEVLEKGGYKFDKSQYLPGIVAYYSKPDGTMLSFPYNSSSPILYYNKDAFKKAGLDENKPPKTWPEVFEAAKKIKASGASPCGFTSTWLTWIQTENFAAWNNVPYGTNENGLAGTDVKLEINSPLYVEHFQAIADLAKDGTFRYGGRTSEAKQLFTSGECAMLTESSGGLGDVVKSGINYGIGQLPYYEGHGPQNTIPGGASLWVFAGLSDDQYKGIAEFFNFLSQTKIQVKLHEKSGYLPVTLAAYEETKKSDFYEKNPGRETPILQMMGKEPTENSKGVRLVNLPQVRDILNEEFEAMLGGKQDAKTALDNAVKRGNAAIAAAQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: B suis ugpB mutant does not contain SP41 protein. Mutants lacking SP41 production are less invasive, but proliferate in HeLa cells. An isogenic DeltaugpB mutant showed a significant inhibitory effect on Brucella adherence and invasion of human cultured epithelial cells and this effect could be reversed by restoration of the ugpB on a plasmid. (Castañeda-Roldán et al., 2006).
COG COG1653G, under G: Carbohydrate transport and metabolism
References
Castañeda-Roldán et al., 2006: Castañeda-Roldán EI, Ouahrani-Bettache S, Saldaña Z, Avelino F, Rendón MA, Dornand J, Girón JA. Characterization of SP41, a surface protein of Brucella associated with adherence and invasion of host epithelial cells. Cellular microbiology. 2006; 8(12); 1877-1887. [PubMed: 16817909].