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Rv0986

Victor ID 99
Gene Name Rv0986
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 885364
NCBI Protein GI 15608126
Locus Tag Rv0986
Protein Accession NP_215501.1
Other Database IDs UniProtKB-ID: Y986_MYCTU
UniRef100: UniRef100_O53899
UniRef90: UniRef90_O53899
UniRef50: UniRef50_O53899
UniParc: UPI0000139EBC
EMBL: BX842575
EMBL: AE000516
EMBL-CDS: CAA17585.1
EMBL-CDS: AAK45262.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
TCDB: 3.A.1.125.2
EnsemblGenome: EBMYCG00000003804
EnsemblGenome_TRS: EBMYCT00000003806
EnsemblGenome_PRO: EBMYCP00000003806
EnsemblGenome: EBMYCG00000069298
EnsemblGenome_TRS: EBMYCT00000069303
EnsemblGenome_PRO: EBMYCP00000067362
GenomeReviews: AE00051
Taxonomy ID 83332
Gene Starting Position 1101802
Gene Ending Position 1102548
Gene Strand (Orientation) +
Protein Name PROBABLE ADHESION COMPONENT TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER
DNA Sequence 
>gi|57116681:1101802-1102548 Mycobacterium tuberculosis H37Rv, complete genome
CATGAACCGGCAACCTATCGTTCAGCTGAGTAACTTGAGCTGGACATTCCGAGAAGGCGAAACCCGACGA
CAAGTCCTAGACCACATCACCTTCGATTTCGAGCCCGGTGAGTTTGTCGCGCTGCTGGGGCAAAGTGGAA
GTGGTAAAAGCACTTTGCTGAACCTCATCAGTGGCATAGAAAAGCCCACCACAGGTGACGTCACAATTAA
TGGGTTCGCTATCACTCAGAAAACCGAGCGAGACCGGACGTTGTTCCGGCGCGATCAGATTGGCATCGTC
TTTCAATTTTTCAACCTGATTCCCACTCTTACCGTGTTGGAAAATATTACGCTGCCTCAGGAACTGGCCG
GAGTTTCTCAGAGGAAAGCGGCCGTGGTCGCTCGTGACCTTCTCGAAAAAGTGGGCATGGCCGACCGTGA
ACGCACCTTTCCCGATAAACTCTCCGGCGGAGAACAACAACGGGTCGCTATTTCCAGAGCGTTGGCGCAT
AATCCCATGCTGGTGTTAGCCGATGAGCCGACCGGCAACCTGGACTCCGATACCGGGGATAAAGTCTTGG
ATGTTCTGCTTGATCTCACCCGCCAAGCAGGTAAAACCTTAATCATGGCTACGCATAGCCCGTCGATGAC
GCAGCATGCCGACCGGGTAGTCAACTTACAGGGCGGCAGGTTGATACCTGCCGTGAACCGAGAAAATCAA
ACCGACCAGCCGGCCAGCACGATCCTATTGCCCACGTCATATGAATG
Protein Sequence 
>gi|15608126|ref|NP_215501.1| adhesion component ABC transporter ATP-binding protein [Mycobacterium tuberculosis H37Rv] MNRQPIVQLSNLSWTFREGETRRQVLDHITFDFEPGEFVALLGQSGSGKSTLLNLISGIEKPTTGDVTINGFAITQKTERDRTLFRRDQIGIVFQFFNLIPTLTVLENITLPQELAGVSQRKAAVVARDLLEKVGMADRERTFPDKLSGGEQQRVAISRALAHNPMLVLADEPTGNLDSDTGDKVLDVLLDLTRQAGKTLIMATHSPSMTQHADRVVNLQGGRLIPAVNRENQTDQPASTILLPTSYE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: Rv0986 mutant is attenuated in survival within macrophages (Pethe et al., 2004).
COG COG1136V, under V: Defense mechanisms
References
Pethe et al., 2004: Pethe K, Swenson DL, Alonso S, Anderson J, Wang C, Russell DG. Isolation of Mycobacterium tuberculosis mutants defective in the arrest of phagosome maturation. Proceedings of the National Academy of Sciences of the United States of America. 2004; 101(37); 13642-13647. [PubMed: 15340136].