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oxyR

Victor ID 987
Gene Name oxyR
Sequence Strain (Species/Organism) Brucella suis 1330
NCBI Gene ID 1164792
NCBI Protein GI 23500107
Locus Tag BRA0354
Genbank Accession AE014292
Protein Accession NP_699547
Other Database IDs UniProtKB-ID: Q8FWU1_BRUSU
UniRef100: UniRef100_A9MEA3
UniRef90: UniRef90_A5VU64
UniRef50: UniRef50_A5VU64
UniParc: UPI00000DD902
EMBL: AE014292
EMBL-CDS: AAN33552.1
RefSeq_NT: NC_004311.2
HSSP: Q9WXC7
GenomeReviews: AE014292_GR
KEGG: bms:BRA0354
NMPDR: fig|204722.1.peg.2456
TIGR: BRA0354
HOGENOM: HBG685425
OMA: QPGRSIG
ProtClustDB: CLSK886277
BioCyc: BSUI204722:BR_A0354-MONOMER
Taxonomy ID 204722
Chromosome No II
Gene Starting Position 335292
Gene Ending Position 336245
Gene Strand (Orientation) -
Protein Name transcriptional regulator OxyR
Protein pI 7.76
Protein Weight 33797.88
Protein Length 317
Protein Note similar to GP:4098965, and GP:4098965; identified by sequence similarity; putative
DNA Sequence 
>gi|56968493:335292-336245 Brucella suis 1330 chromosome chromosome II, complete sequence
ATTAAGAATATGAAGGGGTAGAAGGGTTATCCAATAAAGTATCAATCTTGGAAGGATCTATCTTTAGTTT
ATTAGCACTTTCTGCAATACATTCGGCGAGCGCTCGAAAACCTTTCCCGCGCATACTTTGCCGCCGCCAG
AAAAGTGCAATCTCGCGCTTGGGTTGTTCCCCCTCGAAAGGCACGATGCGCATATGGTTGCTGCGCGCTT
CGGCACGAACGGCAATTTCGGGGATCAGCGTCAGCCCCATGCCATGGCTGACCATCTGCAAAAGCGTGCT
CATGCTGGTTGCGCCGTATTTCACCAGTTGCCGCTGGGAGGGCAGGGTGCAAACGGCGAGCGCCTGGTCG
CGCATGCAATGGCCTTCCTCCAGCAGCAGAAGTCGTTCCAGCGCGGCATGGTTCTGCGTCATCGGCGAGG
CGAGAACCGTATGGTCGTTGGTGGAGGTGGCGATGAGAAAACGGTCGTCGAAAAGCTTCTGGTGGCTAAG
CTTCTCGTCATCGATCGGCAAGGCGGCAACAATGGCGTCCAGATCGCCAGCGTGCAGTTCTTCCAGCAAT
TTTGCCGTGACGCTCTCGCGCAACTGTAGGCGGAAAGATGGATGCTGTTCGTGCAGCAGGGGAATGAGAA
CCGGCACGAGATAGGGCGCGACGGTGGGAATGATTCCGAGCTTTATGCCCGTTTGCAGCACGCCACGGCT
TTGTGCGGCTATTTCCTCCAGCTTCTGTAATTCGCGCAGGATGGCCTTGATGCCAGGATAAAGGTGCTTT
CCAAGCTCGGTCATGATAACCTGCCGCTGCGAGCGCTCGAAAAGCGGTGCACCCGCGATTGCCTCCATTT
CTGCAATCTGGGCGGAGAGTGCTGGTTGTGAAACATGGGCCAGTTCGGCGGCCTTGCGAAAATGCAGGGT
AGAGGCAAGCGCATCGAAATAGCGTATTTGACGGACTGTAAACA
Protein Sequence 
>gi|23500107|ref|NP_699547.1| transcriptional regulator OxyR [Brucella suis 1330]
MFTVRQIRYFDALASTLHFRKAAELAHVSQPALSAQIAEMEAIAGAPLFERSQRQVIMTELGKHLYPGIK
AILRELQKLEEIAAQSRGVLQTGIKLGIIPTVAPYLVPVLIPLLHEQHPSFRLQLRESVTAKLLEELHAG
DLDAIVAALPIDDEKLSHQKLFDDRFLIATSTNDHTVLASPMTQNHAALERLLLLEEGHCMRDQALAVCT
LPSQRQLVKYGATSMSTLLQMVSHGMGLTLIPEIAVRAEARSNHMRIVPFEGEQPKREIALFWRRQSMRG
KGFRALAECIAESANKLKIDPSKIDTLLDNPSTPSYS
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: The transcription product of Brucella abortus oxyR binds to the B abortus catalase promoter region. A gene replacementdeletion Brucella oxyR mutant exhibits increased sensitivity to prolonged exposure to H2O2 and is unable to adapt to H2O2 in the environment (Kim and Mayfield, 2000).
COG COG0583K, under K: Transcription
References
Kim and Mayfield, 2000: Kim JA, Mayfield J. Identification of Brucella abortus OxyR and its role in control of catalase expression. Journal of bacteriology. 2000; 182(19); 5631-5633. [PubMed: 10986275].