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vacB from Shigella flexneri 2a str. 2457T

Victor ID 954
Gene Name vacB from Shigella flexneri 2a str. 2457T
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 2457T
NCBI Gene ID 1080803
NCBI Protein GI 161486368
Locus Tag S4602
Protein Accession NP_839722.2
Other Database IDs UniProtKB-ID: RNR_SHIFL
UniRef100: UniRef100_P30851
UniRef90: UniRef90_P21499
UniRef50: UniRef50_P21499
UniParc: UPI00001344B8
EMBL: AE005674
EMBL: AE014073
EMBL: D11024
EMBL-CDS: AAN45751.1
EMBL-CDS: AAP19534.1
EMBL-CDS: BAA01777.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
EnsemblGenome: EBESCG00000085322
EnsemblGenome_TRS: EBESCT00000086277
EnsemblGenome_PRO: EBESCP00000083099
EnsemblGenome: EBESCG00000088639
EnsemblGenome_TRS: EBESCT00000089595
EnsemblGenome_PRO: EBESCP00000086231
GenomeR
Taxonomy ID 198215
Gene Starting Position 4503631
Gene Ending Position 4506072
Gene Strand (Orientation) +
Protein Name exoribonuclease R
DNA Sequence 
>gi|30061571:4503631-4506072 Shigella flexneri 2a str. 2457T, complete genome
GATGTCACAAGATCCTTTCCAGGAACGCGAAGCTGAAAAATACGCGAATCCCATCCCTAGTCGGGAATTT
ATCCTCGAACATTTAACCAAACGTGAAAAACCGGCCAGCCGTGATGAGCTGGCGGTAGAACTGCACATTG
AAGGCGAAGAGCAGCTTGAAGGCCTGCGTCGCCGCCTGCGCGCGATGGAGCGCGATGGTCAACTGGTCTT
CACTCGTCGTCAGTGCTATGCGCTGCCGGAACGCCTCGACCTGGTGAAAGGTACCGTTATTGGTCACCGT
GATGGCTACGGCTTTCTGCGGGTTGAAGGGCGTAAAGATGATTTGTATCTCTCCAGCGAGCAGATGAAAA
CCTGCATTCATGGCGATCAGGTGCTGGCGCAGCCGCTGGGTGCTGACCGTAAAGGTCGTCGTGAAGCGCG
TATTGTCCGCGTACTGGTGCCAAAAACCAGCCAGATTGTTGGTCGCTACTTTACCGAAGCGGGCGTCGGC
TTTGTGGTTCCTGACGATAGCCGTCTGAGCTTCGATATCTTAATCCCGCCCGATCAGATCATGGGCGCGC
GGATGGGCTTTGTGGTCGTAGTCGAACTGACTCAGCGTCCGACTCGCCGCACCAAAGCGGTGGGTAAAAT
CGTCGAAGTGCTGGGCGACAATATGGGCACCGGCATGGCGGTTGATATCGCTCTGCGTACCCATGAAATT
CCGTATATCTGGCCGCAGGCTGTTGAGCAACAGGTTGCGGGGCTGAAAGAAGAAGTGCCGGAAGAAGCAA
AAGCGGGCCGTGTCGATTTGCGCGATTTACCGCTGGTCACCATTGATGGCGAAGACGCCCGTGACTTTGA
CGATGCAGTTTACTGCGAGAAAAAACGCGGCGGCGGCTGGCGTTTATGGGTCGCGATTGCCGACGTCAGC
TACTATGTGCGTCCGCCAACGCCGCTGGACAGAGAAGCGCGTAACCGTGGCACGTCGGTGTACTTCCCTT
CGCAGGTTATCCCGATGCTGCCGGAAGTGCTCTCTAACGGCCTGTGTTCGCTCAACCCGCAGGTAGACCG
CCTGTGTATGGTGTGCGAGATGACGGTTTCGTCGAAAGGCCGCCTGACGGGCTACAAATTCTACGAAGCG
GTGATGAGCTCTCACGCGCGTCTGACCTACACCAAAGTCTGGCATATTCTGCAGGGCGATCAGGATCTGC
GCGAGCAGTACGCCCCGCTGGTTAAGCATCTCGAAGAGTTGCATAACCTCTATAAAGTGCTGGATAAAGC
CCGTGAAGAACGCGGTGGGATCTCATTTGAGAGCGAAGAAGCGAAGTTCATTTTCAACGCTGAACGCCGT
ATTGAACGTATCGAACAGACCCAGCGTAACGACGCGCACAAATTAATTGAAGAGTGCATGATTCTGGCGA
ATATCTCGGCGGCGCGTTTCGTTGAGAAAGCGAAAGAACCGGCACTGTTCCGTATTCACGACAAGCCGAG
CACCGAAGCGATTACCTCTTTCCGTTCAGTGCTGGCGGAGCTGGGGCTGGAGCTGCCGGGTGGTAACAAG
CCGGAACCGCGTGACTACGCGGAACTGCTGGAGTCGGTTGCCGACCGTCCTGATGCAGAAATGCTGCAAA
CCATGCTGCTACGCTCGATGAAACAGGCGATTTACGATCCAGAAAACCGTGGTCACTTCGGTCTGGCATT
GCAGTCCTATGCGCACTTTACTTCGCCGATTCGTCGTTATCCTGACCTGACGCTGCACCGCGCCATTAAA
TATCTGCTGGCGAAAGAGCAGGGGCATCAGGGCAACACCACTGAAACCGGCGGCTACCATTATTCGATGG
AAGAGATGTTGCAACTGGGTCAGCACTGTTCGATGGCGGAACGTCGTGCCGACGAAGCAACGCGCGATGT
CGCTGACTGGCTGAAGTGTGACTTCATGCTCGACCAGGTAGGTAACGTCTTTAAAGGCGTAATTTCCAGC
GTCACTGGCTTTGGCTTCTTCGTCCGTCTGGACGACTTGTTCATTGATGGTCTGGTCCATGTCTCTTCGC
TGGACAATGACTACTATCGCTTTGACCAGGTAGGGCAACGCCTGATGGGGGAATCCAGCGGCCAGACTTA
TCGCCTGGGCGATCGCGTGGAAGTTCGCGTCGAAGCGGTTAATATGGACGAGCGCAAAATCGACTTTAGT
CTGATCTCCAGTGAACGCGCACCGCGCAACGTCGGTAAAACGGCGCGCGAGAAAGCGAAAAAAGGCGATG
CAGGCAAAAAAGGCGGCAAGCGTTGTCAGGTCGGTAAAAAGGTAAACTTTGAGCCAGACAGCGCCTTCCG
CGGTGAGAAAAAAACGAAGCCGAAAGCGGCGAAGAAAGACGCGAGAAAAGCGAAAAAGCCATCGGCGAAA
ACGCAGAAAATAGCCGCAGCGACCAAAGCGAAGCGTGCGGCGAAGAAAAAAGTGGCAGAGTG
Protein Sequence 
>gi|161486368|ref|NP_839722.2| exoribonuclease R [Shigella flexneri 2a str. 2457T] MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVELHIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVEGRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEAGVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVIPMLPEVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQGDQDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQTQRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLELPGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHFTSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRADEATRDVADWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYYRFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTAREKAKKGDAGKKGGKRCQVGKKVNFEPDSAFRGEKKTKPKAAKKDARKAKKPSAKTQKIAAATKAKRAAKKKVAE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: vacB mutants had attenuated invasion of MK2 cells compared to the wild-type strain (Tobe et al., 1992).
COG COG0557K, under K: Transcription
References
Tobe et al., 1992: Tobe T, Sasakawa C, Okada N, Honma Y, Yoshikawa M. vacB, a novel chromosomal gene required for expression of virulence genes on the large plasmid of Shigella flexneri. Journal of bacteriology. 1992; 174(20); 6359-6367. [PubMed: 1400189].