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ompR from Shigella flexneri 2a str. 2457T

Victor ID 952
Gene Name ompR from Shigella flexneri 2a str. 2457T
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 2457T
NCBI Gene ID 1080544
NCBI Protein GI 30065312
Locus Tag S4339
Protein Accession NP_839483.1
Other Database IDs UniProtKB-ID: OMPR_SHIFL
UniRef100: UniRef100_P0AA18
UniRef90: UniRef90_P0AA18
UniRef50: UniRef50_P0AA18
UniParc: UPI0000000AFA
EMBL: AJ288905
EMBL: AE005674
EMBL: AE014073
EMBL: AF030314
EMBL-CDS: CAC34268.1
EMBL-CDS: AAN44885.1
EMBL-CDS: AAP19294.1
EMBL-CDS: AAB84276.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
EnsemblGenome: EBESCG00000087532
EnsemblGenome_TRS: EBESCT00000088488
EnsemblGenome_PRO: EBESCP00000085310
EnsemblGenome: EBESCG00000088828
EnsemblGenome_TRS: EBESCT00000089784
Ensem
Taxonomy ID 198215
Gene Starting Position 4266805
Gene Ending Position 4267524
Gene Strand (Orientation) +
Protein Name osmolarity response regulator
DNA Sequence 
>gi|30061571:4266805-4267524 Shigella flexneri 2a str. 2457T, complete genome
AATGCAAGAGAACTACAAGATTCTGGTGGTCGATGACGACATGCGCCTGCGTGCGCTGCTGGAACGTTAT
CTCACCGAACAAGGCTTCCAGGTTCGAAGCGTCGCTAATGCAGAACAGATGGATCGCCTGCTGACTCGTG
AATCTTTCCATCTTATGGTACTGGATTTAATGTTACCTGGTGAAGATGGCTTGTCGATTTGCCGACGTCT
TCGTAGTCAGAGCAACCCGATGCCGATCATTATGGTGACGGCGAAAGGGGAAGAAGTGGACCGTATCGTA
GGCCTGGAGATTGGCGCTGACGACTACATTCCAAAACCGTTTAACCCGCGTGAACTGCTGGCCCGTATTC
GTGCGGTGCTGCGTCGTCAGGCGAACGAACTGCCAGGCGCACCGTCACAGGAAGAGGCGGTAATTGCTTT
CGGTAAGTTCAAACTTAACCTCGGTACGCGCGAAATGTTCCGCGAAGATGAGCCGATGCCGCTCACCAGC
GGTGAGTTTGCGGTACTGAAGGCACTGGTCAGCCATCCGCGTGAGCCGCTCTCCCGCGATAAGCTGATGA
ACCTTGCCCGTGGTCGTGAATATTCCGCAATGGAACGCTCCATCGACGTGCAGATTTCGCGTCTGCGCCG
CATGGTAGAAGAAGATCCAGCGCATCCGCGTTACATTCAGACCGTTTGGGGCCTGGGCTACGTCTTTGTA
CCGGACGGCTCTAAAGCATG
Protein Sequence 
>gi|30065312|ref|NP_839483.1| osmolarity response regulator [Shigella flexneri 2a str. 2457T] MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMPLTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPDGSKA
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mutant of the ompB locus (both the envZ and ompR genes) showed attenuated virulence in HeLa cells, and a weak response to a Serany test (Bernardini et al., 1990).
COG COG0745TK, under T: Signal transduction mechanisms; K: Transcription
References
Bernardini et al., 1990: Bernardini ML, Fontaine A, Sansonetti PJ. The two-component regulatory system ompR-envZ controls the virulence of Shigella flexneri. Journal of bacteriology. 1990; 172(11); 6274-6281. [PubMed: 2121709].