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iucA from Shigella flexneri 2a str. 2457T

Victor ID 951
Gene Name iucA from Shigella flexneri 2a str. 2457T
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 2457T
NCBI Gene ID 1080262
NCBI Protein GI 30065052
Locus Tag S4056
Protein Accession NP_839223.1
Other Database IDs UniProtKB-ID: Q9XCH4_SHIFL
UniRef100: UniRef100_Q31T55
UniRef90: UniRef90_Q47316
UniRef50: UniRef50_Q47316
UniParc: UPI00000B745B
EMBL: AF141323
EMBL: AE005674
EMBL: AE014073
EMBL-CDS: AAD44746.1
EMBL-CDS: AAN45161.2
EMBL-CDS: AAP19034.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
EnsemblGenome: EBESCG00000087241.
EnsemblGenome_TRS: EBESCT00000088196
EnsemblGenome_PRO: EBESCP00000085018
EnsemblGenome: EBESCG00000089338.
EnsemblGenome_TRS: EBESCT00000090294
EnsemblGenome_PRO: EBESCP00000086930
Taxonomy ID 198215
Gene Starting Position 3952683
Gene Ending Position 3954464
Gene Strand (Orientation) -
Protein Name siderophore biosynthesis protein
DNA Sequence 
>gi|30061571:3952683-3954464 Shigella flexneri 2a str. 2457T, complete genome
TTCAGACCTCCTGAGCCTGCAGCGGGTTAGCGAAATCGAAATAGATCACCGAAGGGTCAACAATGGTGTT
CTCGTTATGATCGTTCAGATAACAGAAAAAGTTACCTTTTACGTTCCAGTACGGACTTTCCAGCACGTAG
TTGAGACAGGTTTTATGAGTCACCTGATCACGCACTTCAGCCAGCGATGCTCGTACACGAGCCATCAGAT
TCGATTCGCTGTCCAGCCCGGCAGCCCCCAGCGCAGCGGTCACAGCAAAAGTGGAGTTAACCAGCAGGTA
ATAAGGGAAATAGCGCAGCAACTGCTCATGGGTGAAAATATTTTCCGCCTGCGCCTCGCCAATAGAATCG
AGCCAGTCTGTCGCGTGAGGCATAAAAGCGCTGCCCTGACAGTCACGGTAAATAAATCCGACCGGCAGAT
CCCCAAGCATCTGGACAAGAATATTTTGCTGATGCGCCAGCAGCACCAGGCCGTAATCCGCTTCAGCCGT
AAACAGCGGCTTTAGCACTTGCTGACAGTATGCATCAACCCATGCATGGGCGGCCTGTTGCACAGTGATA
CCGAGGCGATCGCTCAGGCGTTTTACCGCCGAAACCAGCAGCGAATCACCGCCATCAGGTGCGGCCTGAG
TCAGGGAGACCAGTACGTTAGTCTGGCTTTTCGGCTGATCCACCAGCAGATTTTCACGCAGGGCAAACAG
ACTTTCCTGCATGATGTTGCCGTTAAGATCGAGCAGCCCGGCCCAGCCATCCTCCTGCATTACCCGGAAA
GTCGGGAAGCGGACCTGTAGCATCTGCCAGCCGTCGGTTTGAGCCAGGCGTGCCAGGCGCATCCCACGCT
TCACTTCTTTCACGGACAGAGTACGGATGGAGTTGGTCAGCCGTACGCTCAGGGAGAACTTGATCATATC
GCGGCTGGTGGCACAGTAGAGGGAACGGGAAGAGGTGGTCGGCAGCCACGACGTGCCGGCCTCACCTAAG
TCTTTAATCAGCCCTTTAGCAACAAGTGCCTGGCACCACCCCTGCTGCAAAAGATATTCCCCCTGCCACG
GGTGCAACGGGAACAGCCATTGGTTGTCACTTAATTCGTTGAGTAACTGAGGCGCATTCTCTGCGGCAAA
TCGCGTCAGCCGCTGTTGAAGGTTGAGATGCAAACTTTCACCGGCGATTTGCGTTTTATCCACCGAAAAC
CACCGCAGTGGGAAGTGGGGTGCCATATCAGGCAGGTAGCGTTCAGCCTCCCGCCGGTTAAACGGTTCAT
GAGACTTAGGCGCAGGGTGGAAAGCGTGTCCTGTCAGCAGCGCCTGCTCAGCCTCGCCAAAATTCAACGC
TTTTTCACGCAGAGCGGCCCAGTCATGACGGGCATCAATTGCCTGTTGCGTATGGACATGGCTTTCCAGC
ACGCGCTGGTGGAAAGTTTCGCAGAGGGGAACGGGCAGAAACAGTTGATGGCGTAGCTTATCAATAATAA
GCCGGGAGAGAGTGGTAAAGTCGACAGGATAACTGCCTGATGCCGTGACCAGACGTGCAGGAAATGCAAA
GCGGTGATGCTGGGTTGGGGAGAAATAAGCCACTCTGAAATGGAGCGATTTCTGCTCATCCAGCGGGATG
AGCAATTCGTCTGGCGGGTATTCTGTCAGTTTCCAGTCTGTGGTTTCACGAATCAGTGCATTCAGGAAGC
ACTGCGCAGCCACATCTGTGGCTGGTTTTTCAGAGGGCAGGGTCATAGTCAAACAGCTCCCACACAGTAA
AATAATAACAATTATGTCAATAATGATTCTCA
Protein Sequence 
>gi|30065052|ref|NP_839223.1| siderophore biosynthesis protein [Shigella flexneri 2a str. 2457T] MRIIIDIIVIILLCGSCLTMTLPSEKPATDVAAQCFLNALIRETTDWKLTEYPPDELLIPLDEQKSLHFRVAYFSPTQHHRFAFPARLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLCETFHQRVLESHVHTQQAIDARHDWAALREKALNFGEAEQALLTGHAFHPAPKSHEPFNRREAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDNQWLFPLHPWQGEYLLQQGWCQALVAKGLIKDLGEAGTSWLPTTSSRSLYCATSRDMIKFSLSVRLTNSIRTLSVKEVKRGMRLARLAQTDGWQMLQVRFPTFRVMQEDGWAGLLDLNGNIMQESLFALRENLLVDQPKSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSAFMPHATDWLDSIGEAQAENIFTHEQLLRYFPYYLLVNSTFAVTAALGAAGLDSESNLMARVRASLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFANPLQAQEV
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: iuc mutants are attenuated in chicken embryos and rabbit ileal loops (Wyckoff et al., 2009).
COG COG4264Q, under Q: Secondary metabolites biosynthesis, transport and catabolism
References
Wyckoff et al., 2009: Wyckoff EE, Boulette ML, Payne SM. Genetics and environmental regulation of Shigella iron transport systems. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. 2009; 22(1); 43-51. [PubMed: 19130265].