Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

hemN

Victor ID 94
Gene Name hemN
Sequence Strain (Species/Organism) Mycobacterium tuberculosis H37Rv
NCBI Gene ID 885300
NCBI Protein GI 15609525
Locus Tag Rv2388c
Protein Accession NP_216904.1
Other Database IDs UniProtKB-ID: HEMN_MYCTU
UniRef100: UniRef100_P71756
UniRef90: UniRef90_P71756
UniRef50: UniRef50_P71756
UniParc: UPI000012C5A7
EMBL: BX842579
EMBL: AE000516
EMBL-CDS: CAB03737.1
EMBL-CDS: AAK46752.1
RefSeq_NT: NC_000962.2
RefSeq_NT: NC_002755.2
EnsemblGenome: EBMYCG00000001339
EnsemblGenome_TRS: EBMYCT00000001339
EnsemblGenome_PRO: EBMYCP00000001339
EnsemblGenome: EBMYCG00000072174
EnsemblGenome_TRS: EBMYCT00000072179
EnsemblGenome_PRO: EBMYCP00000070238
GenomeReviews: AE000516_GR
GenomeReviews
Taxonomy ID 83332
Gene Starting Position 2682014
Gene Ending Position 2683141
Gene Strand (Orientation) -
Protein Name coproporphyrinogen III oxidase
DNA Sequence 
>gi|57116681:2682014-2683141 Mycobacterium tuberculosis H37Rv, complete genome
GTTAGCCCAGCAGAGTGCGCACCACCGCGTCGGCCAGCAATCGCCCCCGGCCGGTGAGGACCAGTCGGTC
GCCGTGGTAGTCCAGCAATCCGTCGGCCAACACCGCCTCGGCACGTTCCCGTTCGGCAGCCCCTAGCCGG
GCGAGCGGTAGCCCCTGGCGCAGCCGGACCTTCAGCAACACGTCTTCGGTGTGCAAAGCGTCGGCGCCCA
GCTGCTCGAAGCCCGCTACCGGCAACGTCGCCCCGGCCAGTATCTCGGCGTAAGTGTTGGGGTGCTTGAC
ATTCCACCAGCGTGTCACGCCAATGTAGCCGTGCGCGCCCGGACCTGCGCCCCACCACTGGCCACCGTCC
CAATAACCCAGGTTGTGCCGGCACTCGCCGCCCGGTCGACACCAATTGGACACCTCGTACCAGGCAAACC
CGGCCGCCGACAGCCGAGCATCGACCAACTCGTAGCGATGCGCCAGCACGTCGTCATCGGGCGCGGCCAG
CTCACCACGCCGAACCCGGCGAGCCAGTGCCGTGCCGTGCTCGACGACCAAGGCATACGCGGACACATGA
TCCACACCGGCCTGCACCGCGGCGTCCACTGAGCGCACCAGGTCGTCGTCGGACTCCCCCGGGGTTCCAT
AGATCAGGTCGAGGTTGACGTGTGTGAAGCCCTCCGCTATCGCCTCGGTGGCCGCGGCCGCCGCCCGGCC
CGGCGAGTGCACCCGGTCCAAGGTTGCCAGCACCCTCGGGGCCACCGACTGCATGCCGAGCGACACCCGC
GTGTAACCGGCCGCGCGGATCGTGGCGAAGAACTCCGGCCACGTCGACTCGGGGTTGGCCTCGGTGCTGA
CTTCGGCGTCGGGCGCCAGCACAAAGTGGTCCCGCACCATGTCCAGCAACGTGGCCAGGCGCTCCCCCCC
GAGCAGCGATGGCGTCCCGCCACCCACATACACGGTATGCACCGTCGGTGCGTCCAGCTTGGCGGCCGCC
AGTTCGAGCTCCGCCCGCAGCGCCAGCAGCCAACGGTCCGGGCTGACGCCACCCAGCTGGGCCGGGGTGT
AGGTATTGAAGTCGCAGTACCCGCAACGGGTCAGGCAGAACGGGACGTGCAGGTAGACCCCGAACGGTTG
TCCGGGCA
Protein Sequence 
>gi|15609525|ref|NP_216904.1| oxygen-independent coproporphyrinogen III oxidase [Mycobacterium tuberculosis H37Rv] MPGQPFGVYLHVPFCLTRCGYCDFNTYTPAQLGGVSPDRWLLALRAELELAAAKLDAPTVHTVYVGGGTPSLLGGERLATLLDMVRDHFVLAPDAEVSTEANPESTWPEFFATIRAAGYTRVSLGMQSVAPRVLATLDRVHSPGRAAAAATEAIAEGFTHVNLDLIYGTPGESDDDLVRSVDAAVQAGVDHVSAYALVVEHGTALARRVRRGELAAPDDDVLAHRYELVDARLSAAGFAWYEVSNWCRPGGECRHNLGYWDGGQWWGAGPGAHGYIGVTRWWNVKHPNTYAEILAGATLPVAGFEQLGADALHTEDVLLKVRLRQGLPLARLGAAERERAEAVLADGLLDYHGDRLVLTGRGRLLADAVVRTLLG
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: attenuated in mice (Sassetti and Rubin, 2003).
COG COG0635H, under H: Coenzyme transport and metabolism
References
Sassetti and Rubin, 2003: Sassetti CM, Rubin EJ. Genetic requirements for mycobacterial survival during infection. Proceedings of the National Academy of Sciences of the United States of America. 2003; 100(22); 12989-12994. [PubMed: 14569030].