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rfc

Victor ID 937
Gene Name rfc
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 2457T
NCBI Gene ID 1078521
NCBI Protein GI 30063485
Locus Tag S2219
Protein Accession NP_837656.1
Other Database IDs UniProtKB-ID: RFC_SHIFL
UniRef100: UniRef100_P37784
UniRef90: UniRef90_P37784
UniRef50: UniRef50_P37784
UniParc: UPI00001337F7
EMBL: X71970
EMBL: AE005674
EMBL: AE014073
EMBL-CDS: CAA50774.1
EMBL-CDS: AAN43636.1
EMBL-CDS: AAP17465.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
EnsemblGenome: EBESCG00000086365
EnsemblGenome_TRS: EBESCT00000087320
EnsemblGenome_PRO: EBESCP00000084142
EnsemblGenome: EBESCG00000090788
EnsemblGenome_TRS: EBESCT00000091744
EnsemblGenome_PRO: EBESCP00000088380
GenomeR
Taxonomy ID 198215
Gene Starting Position 2093826
Gene Ending Position 2094974
Gene Strand (Orientation) -
Protein Name O-antigen polymerase
DNA Sequence 
>gi|30061571:2093826-2094974 Shigella flexneri 2a str. 2457T, complete genome
TTTATTTTGCTCCAGAAGTGAGGTTATTACTAATTTGGATATTTTCTATAGAAAATACCCATAAAACTAC
AACGCCTATAATAAAAATTCCCATGGGTGTAAAAAGAAATGGATTAGTTATAGAAACGGTAATACTGAAA
AAAAGTATTAACGACATCATTAATGATGTTTTTGTACTATTTAAAAAATAGCCTTTCAAAAAGATAAGCA
ACATAGGAACTAATGATATAAATACACCAATAACGCCTGTTTTCTGAAGTATCTCAAGAGGTACTATTTC
AATCCTTAATCGATCTAATATAAATGAACCAAATCCTCTTCCAAACAAGAACGTCGCTAAATCAACATTT
TTATAATAAAAATATAAATCATTAAATCTAACAGAGTCAGAATCTTCACTGCGTGATCCGACCATGTAAA
GCATAATTATAAATAGAACGCTGCCCAATATTATTATAATAGTATTTAAATATAGCTTATGTAATTTAAA
ACTGGCTAATAACAGTGATAATGTTGTAAAAAGTAATACACCTCTTGATTCTGTCAATAATATCGCAAGC
ACTATTATGAGACATTTTAAATATTTTTTGTCGACAAAACTGATAATCGCACCGACACCAAAAAAGTAGA
AGGATTTGGAAAAAAAAGCCCCATCGGGACGAAAAAAGAACTCGCTAGTCAATGATAAGTGTTCATAAAT
TAAATTAAAATTTAACAAACCGAAATTCAACAAAATTATGTATGAAATATATAACAGTGATCCATATAAT
GCAAATGCATTAACTATTTTAATAAAAATCTCACATGAAAATACTTTTAAAGTATATCTTAGTGTAAATA
GATATATAAGTGACAGCATAAAAAGGTATGGTTGCACATCAAACAGTATATCATTTATTTTATTACCAGC
TAATAAGCCGACAAAGAAGCCATAAAAAGGAAATAAAAGCAACCATATAAAAAGACTGACACATTTTTGG
GTGATTGAAAAATTGAATGTAACTAAATTAAAAATTAAAAGTATAAAACTAAATACAAATAATAAATATC
GCAAAGGGAATATTCCCAATGGCTCCAGTAATCTTCCACCACCACCAATAATCAGTTCAATACATAAAAA
TGTTATAAAAATTTTATTTATATTATTCA
Protein Sequence 
>gi|30063485|ref|NP_837656.1| O-antigen polymerase [Shigella flexneri 2a str. 2457T] MNNINKIFITFLCIELIIGGGGRLLEPLGIFPLRYLLFVFSFILLIFNLVTFNFSITQKCVSLFIWLLLFPFYGFFVGLLAGNKINDILFDVQPYLFMLSLIYLFTLRYTLKVFSCEIFIKIVNAFALYGSLLYISYIILLNFGLLNFNLIYEHLSLTSEFFFRPDGAFFSKSFYFFGVGAIISFVDKKYLKCLIIVLAILLTESRGVLLFTTLSLLLASFKLHKLYLNTIIIILGSVLFIIMLYMVGSRSEDSDSVRFNDLYFYYKNVDLATFLFGRGFGSFILDRLRIEIVPLEILQKTGVIGVFISLVPMLLIFLKGYFLNSTKTSLMMSLILFFSITVSITNPFLFTPMGIFIIGVVVLWVFSIENIQISNNLTSGAK
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: rfc mutant is attenuated in invasion of T84 cell monolayer and adhesion to epithelial cells (Köhler et al., 2002).
References
Köhler et al., 2002: Köhler H, Rodrigues SP, McCormick BA. Shigella flexneri Interactions with the Basolateral Membrane Domain of Polarized Model Intestinal Epithelium: Role of Lipopolysaccharide in Cell Invasion and in Activation of the Mitogen-Activated Protein Kinase ERK. Infection and immunity. 2002; 70(3); 1150-1158. [PubMed: 11854195].