Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

tonB from Shigella flexneri 2a str. 2457T

Victor ID 933
Gene Name tonB from Shigella flexneri 2a str. 2457T
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 2457T
NCBI Gene ID 1077715
NCBI Protein GI 30062775
Locus Tag S1341
Protein Accession NP_836946.1
Other Database IDs UniProtKB-ID: Q83RM7_SHIFL
UniRef100: UniRef100_Q31ZU6
UniRef90: UniRef90_P02929
UniRef50: UniRef50_P25945
UniParc: UPI000018F830
EMBL: AE005674
EMBL: AE014073
EMBL-CDS: AAN42868.2
EMBL-CDS: AAP16753.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
HSSP: P94739
EnsemblGenome: EBESCG00000087568.
EnsemblGenome_TRS: EBESCT00000088524
EnsemblGenome_PRO: EBESCP00000085346
EnsemblGenome: EBESCG00000091591.
EnsemblGenome_TRS: EBESCT00000092547
EnsemblGenome_PRO: EBESCP00000089183
GenomeReviews: AE005674
Taxonomy ID 198215
Gene Starting Position 1307267
Gene Ending Position 1307995
Gene Strand (Orientation) +
Protein Name membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins
DNA Sequence 
>gi|30061571:1307267-1307995 Shigella flexneri 2a str. 2457T, complete genome
TATGACTTCAATAACCCTTGATTTACCTCGCCGCTTCCCCTGGCCGACGTTACTTTCGGTCTGCATTCAT
GGTGCTGTTGTGGCGGGGCTGCTCTATACCTCGGTACATCAGGTTATTGAACTACCTGCGCCTGCGCAAC
CAATTTCTGTCACGATGGTTGCGCCTGCTGATCTCGAACCGCCACAAGCCGTTCAGCCGCCACCGGAGCC
GGTGGTAGAGCCAGAACCGGAACCTGAGCCGATCCCCGAACCGCCAAAAGAAGCACCGGTGGTCATTGAA
AAGCCGAAGCCGAAACCTAAGCCAAAACCGAAGCCGGTGAAAAAGGTACAGGAGCAGCCAAAACGCGATG
TCAAACCCGTAGAGTCGCGTCCGGCATCACCGTTTGAAAATACGGCACCCGCGCGCCCCACATCAAGTAC
GGCAACGGCTGCAACCAGCAAGCCGGTTACCAGTGTGGCTTCAGGACCACGCGCATTAAGCCGTAATCAG
CCGCAGTATCCGGCACGAGCACAGGCATTGCGCATTGAAGGGCAGGTTAAAGTTAAATTTGACGTCACGC
CGGATGGTCGCGTGGATAACGTACAAATCCTCTCAGCCAAGCCTGCGAACATGTTTGAGCGTGAGGTGAA
AAATGCGATGCGCAGATGGCGTTATGAGCCGGGTAAGCCAGGCAGTGGGATTGTGGTGAATATCCTGTTT
AAAATTAACGGCACCACCGAAATTCAGTA
Protein Sequence 
>gi|30062775|ref|NP_836946.1| transporter [Shigella flexneri 2a str. 2457T] MTSITLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: tonB mutant is able to invade epithelial cells but is incapable of cell to cell spread (Reeves et al., 2000).
COG COG0810M, under M: Cell wall/membrane/envelope biogenesis
References
Reeves et al., 2000: Reeves SA, Torres AG, Payne SM. TonB is required for intracellular growth and virulence of Shigella dysenteriae. Infection and immunity. 2000; 68(11); 6329-6336. [PubMed: 11035742].