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surA from Shigella flexneri 2a str. 2457T

Victor ID 928
Gene Name surA from Shigella flexneri 2a str. 2457T
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 2457T
NCBI Gene ID 1076439
NCBI Protein GI 30061620
Locus Tag S0052
Protein Accession NP_835791.1
Other Database IDs UniProtKB-ID: SURA_SHIFL
UniRef100: UniRef100_Q1RGE4
UniRef90: UniRef90_Q1RGE4
UniRef50: UniRef50_Q1RGE4
UniParc: UPI0000136242
EMBL: AE005674
EMBL: AE014073
EMBL-CDS: AAN41716.1
EMBL-CDS: AAP15596.1
RefSeq_NT: NC_004337.1
RefSeq_NT: NC_004741.1
EnsemblGenome: EBESCG00000085049
EnsemblGenome_TRS: EBESCT00000086004
EnsemblGenome_PRO: EBESCP00000082826
EnsemblGenome: EBESCG00000088629
EnsemblGenome_TRS: EBESCT00000089585
EnsemblGenome_PRO: EBESCP00000086221
GenomeReviews: AE005674_GR
GenomeReviews
Taxonomy ID 198215
Gene Starting Position 52219
Gene Ending Position 53505
Gene Strand (Orientation) -
Protein Name peptidyl-prolyl cis-trans isomerase SurA
DNA Sequence 
>gi|30061571:52219-53505 Shigella flexneri 2a str. 2457T, complete genome
ATTAGTTGCTCAGGATTTTAACGTAGGCGCTGGCACGTTGTTCCTGCATCCAGCTTGCTGCTTCTTCCGA
GAACTTACGGTTCATCAGCATGCGGTATGCACGATCTTTCTGCGCAGCGTCGGTTTTATCGACATTACGG
GTATCCAGCAGTTCGATTAAATGCCAGCCGAATGAAGAGTGAACCGGTGCACTCATTTGACCTTTGTTCA
GGCGGGTCAGGGCGTCACGGAAGGCTGGATCGAAAATATCTGGTGTAGCCCAGCCGAGATCACCGCCCTG
GTTAGCAGAACCTGGATCCTGCGAGAACTCTTTCGCTGCGGCAGCAAAAGTCGTTTTACCACTCTTGATA
TCAGCAGCAATTTGCTCCAGTTTCACGCGGGCCTGTTCGTCAGTCATGATCGGCGACGGTTTCAGCAGAA
TATGGCGAGCATGAACTTCGGTCACCGAGATATTTTTGCTTTCGCCGCGCAGGTCGTTAACTTTCAGAAT
ATGGAAGCCAACGCCGGAACGAATCGGGCCAACAATGTCGCCTTTCTTCGCGGTGCTTAATGCCTGGGCG
AAGATCCCCGGCAACTCCTGAATACGGCCCCACCCCATCTGGCCGCCGTTCAGCGCCTGCTGGTCGGCAG
AATGAGCAATCGCCAGCTTACCGAAATCAGCGCCGTTACGCGCCTGATCGACAATGGCGCGCGCCTGGCT
TTCCGCTTCGTTCACCTGATCAGAGGTCGGGTTTTCCGGCAGCGGGATCAGGATGTGGCTCAGGTTCAGC
TCAGTGCTGGCGTCGTTTTGGTTACCCACCTGCTGCGCCAGGGATTCGACTTCCTGTGGCAGGATGGTGA
TGCGACGACGCACCTCGTTGTTACGCACTTCAGAGATAATCATCTCTTTGCGGATCTGGTTACGATAAGT
GTTGTAGTTCAGACCATCGTAAGCCAGACGGCTGCGCATCTGATCCAGCGTCATGTTGTTCTGTTTCGCG
ATGTTAGCAATCGCCTGATCCAGCTGCTCATCGGAGATTTTCACTCCCATTTTCTGCCCCATCTGCAGGA
TGATTTGATCCATGATCAAACGTTCCATGATTTGGTGGCGCAGCGTCGCGTCATCAGGAAGCTGCTGCCT
TGCCTGCGCAGCGTTCAGTTTTACCGACTGCATTAATCCATCAACGTCGCTTTCCAGCACGACGCCGTTA
TTGACGACGGCTGCGACTTTATCGACTACCTGGGGGGCAGCGAAACTGGTATTCGCGATCATGGCGATAC
CGAGAAGCAGCGTTTTCCAGTTCTTCA
Protein Sequence 
>gi|30061620|ref|NP_835791.1| peptidyl-prolyl cis-trans isomerase SurA [Shigella flexneri 2a str. 2457T] MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESLAQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: surA mutant is able to infect epithelial cells but is incapable of cell to cell spread (Behrens-Kneip, 2010).
COG COG0760O, under O: Posttranslational modification, protein turnover, chaperones
References
Behrens-Kneip, 2010: Behrens-Kneip S. The role of SurA factor in outer membrane protein transport and virulence. International journal of medical microbiology : IJMM. 2010; 300(7); 421-428. [PubMed: 20447864].