Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

icsB from Shigella flexneri 2a str. 301

Victor ID 920
Gene Name icsB from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1238057
NCBI Protein GI 31983590
Locus Tag CP0132
Protein Accession NP_858265.1
Other Database IDs UniProtKB-ID: ICSB_SHIFL
UniRef100: UniRef100_P33546
UniRef90: UniRef90_P33546
UniRef50: UniRef50_P33546
UniParc: UPI000012D189
EMBL: M86530
EMBL: AL391753
EMBL: AF348706
EMBL: AY206439
EMBL: AF386526
EMBL-CDS: AAD15221.1
EMBL-CDS: CAC05807.1
EMBL-CDS: AAK18450.1
EMBL-CDS: AAP78995.1
EMBL-CDS: AAL72354.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093099
EnsemblGenome_TRS: EBESCT00000094055
EnsemblGenome_PRO: EBESCP00000090262
GenomeReviews: AF386526_GR
KEGG: sfl:CP01
Taxonomy ID 198214
Plasmid No pCP301
Gene Starting Position 114563
Gene Ending Position 116047
Gene Strand (Orientation) -
Protein Name IcsB, invasion protein
DNA Sequence 
>gi|31983523:114563-116047 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence
TCTATATATTAGAATGAGAGTTATTCAATAAAAGCTTATTGATCTGTAATAAGTCGTGAATGTAAAGTTT
GGTTCCAAGATCTGGCGATTTAAGAGAATTGTAATAATCAATAATTTTTATTGATTTTTCGATGATTTCT
TCTTTTTTATCTGTTGCTTCGGTTTTTAATTCGTTTAATACACGAGTCATATTGCTGGGTGCTGATTTTA
CTAAGTATGAGTGGCAAGCGTTGATGACCGCATCAAAGTCTTCTGAAGATACATTTTCAGTAGGATGTTT
GTAAAGTGAAATTGATAAAGGCTTGAATGTTTTTGGTGTGTGGATAAGGTTAATTTTATTGAAACTTTTA
AGATAGCTGCGTCGTAATTGAGTCAATCTGGAAAGATCAAAATCAGATTCAATATACTTCATTATTTCGT
TATAAGACTGATTGAGACTTTCAATGCGTTGCCTAACTTTATTTGCATACGCGTATACATCGTTAGGTGT
AGCAACCAATTTAACGTCAGGGAGTGGAAAGTATATTTCAGAATTTCCTGCTTTAAGAACATTAAGTGCC
ATACCAGCACAGTTTTCAGATTTACTGATTAATTTATAATTTGCCAATTGTCTGAAAGCATCTGCTTTCT
TTTTGCATATAAATTTTGACATGTTTGTTTCATCAAGGCCAAAAAGGTTATGGCTGATTTTACCATCCTT
TGTTTTATTATCACCTGATAATGGAATGTATACTTTATCAGCACTGACCCCCCAATAACCATAGGGGTCT
TTTTTTTGATTAGCTCTGGGAAAAAATATTTTTTTGTTGTTATTTTGATCTTGTTTTGAATTTAATAAGT
TTCTAACCTCTTGGCCTGCATCAAGTCTTTCGGCTGTTTGGTCTGAAATCATATTTAGTTTGTCTTGCTT
ATAGGTATCGACACTGTAACCTGAGCGTTTTTCAAAAAGGTAGTTTATTTCTGTATCTTTTGTAACATTC
CCGCCGGGATACCAGCTGAGATAGGTATGAGTTGGTTCCTGTAGTAAATTGTTTTTTATACTGATACTAG
TATGCCCTAAATGGGTTATGCCTCTATTTCCCCAGCAACGAAAAACTAAATGTCTTTCAAGATTTTTGGC
TGTACCGATGCCATGAAAACGCTCTGCGGTATTCAACATTAATTTGATGTCTCTACCTGTGAAAGAGTGT
TGAATTGAGTTTTTAGCTGCTTCATAGGCGGCAAACGCACTTTCTGCAGATTTTTCGCTAGCTAATGTAT
TGAGGAAAAGCAATAAGGATTTTTGATTCTCTAGTCGATAATTTTTTAGTTGTTCATTTAATATCTGTGA
ATTTATCTTTGCATTAATAGTGCTTAATGTTCTGAAAAAGAGATCCTTTAGGTTGAATTTCTGTGCTATC
AATATAGGTCCATGCTCTGTATCTTCAACGCGTATAGGCCCTTTTGTATTGCTTGCGTCAATGAAATTGC
TAATTTTGAGGATCA
Protein Sequence 
>gi|31983590|ref|NP_858265.1| IcsB, invasion protein [Shigella flexneri 2a str. 301] MILKISNFIDASNTKGPIRVEDTEHGPILIAQKFNLKDLFFRTLSTINAKINSQILNEQLKNYRLENQKSLLLFLNTLASEKSAESAFAAYEAAKNSIQHSFTGRDIKLMLNTAERFHGIGTAKNLERHLVFRCWGNRGITHLGHTSISIKNNLLQEPTHTYLSWYPGGNVTKDTEINYLFEKRSGYSVDTYKQDKLNMISDQTAERLDAGQEVRNLLNSKQDQNNNKKIFFPRANQKKDPYGYWGVSADKVYIPLSGDNKTKDGKISHNLFGLDETNMSKFICKKKADAFRQLANYKLISKSENCAGMALNVLKAGNSEIYFPLPDVKLVATPNDVYAYANKVRQRIESLNQSYNEIMKYIESDFDLSRLTQLRRSYLKSFNKINLIHTPKTFKPLSISLYKHPTENVSSEDFDAVINACHSYLVKSAPSNMTRVLNELKTEATDKKEEIIEKSIKIIDYYNSLKSPDLGTKLYIHDLLQINKLLLNNSHSNI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: icsB mutants are attenuated in guinea pig eyes (Ogawa et al., 2003).
References
Ogawa et al., 2003: Ogawa M, Suzuki T, Tatsuno I, Abe H, Sasakawa C. IcsB, secreted via the type III secretion system, is chaperoned by IpgA and required at the post-invasion stage of Shigella pathogenicity. Molecular microbiology. 2003; 48(4); 913-931. [PubMed: 12753186].