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ipgA from Shigella flexneri 2a str. 301

Victor ID 913
Gene Name ipgA from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1238046
NCBI Protein GI 31983579
Locus Tag CP0131
Protein Accession NP_858264.1
Other Database IDs UniProtKB-ID: IPGA_SHIFL
UniRef100: UniRef100_P33547
UniRef90: UniRef90_P33547
UniRef50: UniRef50_P33547
UniParc: UPI000012D7DC
EMBL: M86530
EMBL: AL391753
EMBL: AF348706
EMBL: AF386526
EMBL: AY206439
EMBL-CDS: AAD15222.1
EMBL-CDS: CAC05806.1
EMBL-CDS: AAK18449.1
EMBL-CDS: AAL72343.1
EMBL-CDS: AAP78994.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093193
EnsemblGenome_TRS: EBESCT00000094149
EnsemblGenome_PRO: EBESCP00000090356
GenomeReviews: AF386526_GR
KEGG: sfl:CP01
Taxonomy ID 198214
Plasmid No pCP301
Gene Starting Position 114161
Gene Ending Position 114550
Gene Strand (Orientation) -
Protein Name IpgA, similarities to IpgE, putative chaperone
DNA Sequence 
>gi|31983523:114161-114550 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence
GTTAGTTCACTTCTGAAGTGATGTTTGCAATGGTTAGTTTAATACAAAATAAAAATTCATACAAAGATTC
AATGAGTTCATCAGGTGAAAGATATTTTTTGTAGTGTTTCTTGGTCAAAACACATTGATGAGTATCAGGG
AGAAGACAGATAGAAGAACCATAATCTCTACTCAAAGAGTAGTTAAGGATGAGTATGTGTTCTGGATTAA
TAATATTTTCTGTAAAAAGTTCATGTTCATTAAGAAGTCCGGTCAAAAAGATGTATTCATCATTATCTGT
TATACAAACAGGTATTTGTTCTTCGAGCAATATAAAGGCTTGATTTTTATCGTTAAAATCAAGCTTTGCA
CCTGTTATTTCATAAAGTTTATCATATAGTTTGCGACACA
Protein Sequence 
>gi|31983579|ref|NP_858264.1| chaperone IpgA [Shigella flexneri 2a str. 301] MCRKLYDKLYEITGAKLDFNDKNQAFILLEEQIPVCITDNDEYIFLTGLLNEHELFTENIINPEHILILNYSLSRDYGSSICLLPDTHQCVLTKKHYKKYLSPDELIESLYEFLFCIKLTIANITSEVN
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: transposon mutants of ipgA cannot invade epithelial cells and cannot induce keratoconjunctivitis in mice (Ménard et al., 1993).
References
Ménard et al., 1993: Ménard R, Sansonetti PJ, Parsot C. Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells. Journal of bacteriology. 1993; 175(18); 5899-5906. [PubMed: 8376337].