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ipgB2 from Shigella flexneri 2a str. 301

Victor ID 911
Gene Name ipgB2 from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1238044
NCBI Protein GI 56404000
Locus Tag CP0024
Protein Accession NP_858157.2
Other Database IDs UniProtKB-ID: Q9AJW7_SHIFL
UniRef100: UniRef100_B2U5H7
UniRef90: UniRef90_Q327H0
UniRef50: UniRef50_Q327H0
UniParc: UPI00000B0130
EMBL: AF386526
EMBL: AY879342
EMBL: AL391753
EMBL-CDS: AAL72341.2
EMBL-CDS: AAW64784.1
EMBL-CDS: CAC05777.1
RefSeq_NT: NC_004851.1
PDB: 3LW8
PDB: 3LWN
PDB: 3LXR
PDB: 3LYQ
EnsemblGenome: EBESCG00000093224.
EnsemblGenome_TRS: EBESCT00000094180
EnsemblGenome_PRO: EBESCP00000090387
GenomeReviews: AF386526_GR
KEGG: sfl:CP0024
HOGENOM: HBG683966
OMA: RISLDIN
ProtClustDB: CL
Taxonomy ID 198214
Plasmid No pCP301
Gene Starting Position 20682
Gene Ending Position 21248
Gene Strand (Orientation) +
Protein Name IpgB2, probably secreted by the Mxi-Spa secretion machinery
DNA Sequence 
>gi|31983523:20682-21248 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence
AATGCTTGGAACATCTTTTAATAATTTTGGAATCAGTTTATCTCACAAAAGATATTTTTCAGGAAAGGTG
GATGAGATTATCCGCTGTACAATGGGGAAAAGGATAGTAAAAATATCATCAACCAAAATAAATACTAGTA
TTTTGAGCTCTGTTTCAGAACAAATCGGTGAAAATATTACAGATTGGAAAAATGATGAAAAAAAAGTCTA
CGTATCCCGGGTGGTAAACCAATGTATTGATAAGTTTTGTGCAGAACACAGCCGAAAAATCGGCGATAAT
CTCCGTAAACAGATATTTAAACAGGTTGAGAAAGATTATCGCATTTCTCTAGACATCAATGCTGCACAAA
GTTCCATAAATCATCTTGTATCAGGAAGCAGTTATTTCAAAAAGAAAATGGACGAACTTTGTGAAGGGAT
GAATAGAAGCGTTAAAAATGATACAACAAGCAATGTTGCAAATCTTATTTCCGATCAGTTTTTTGAGAAA
AATGTGCAATATATTGATCTAAAGAAATTACGTGGGAATATGAGTGACTATATTACAAATTTAGAATCGC
CTTTCTG
Protein Sequence 
>gi|56404000|ref|NP_858157.2| hypothetical protein CP0024 [Shigella flexneri 2a str. 301] MLGTSFNNFGISLSHKRYFSGKVDEIIRCTMGKRIVKISSTKINTSILSSVSEQIGENITDWKNDEKKVYVSRVVNQCIDKFCAEHSRKIGDNLRKQIFKQVEKDYRISLDINAAQSSINHLVSGSSYFKKKMDELCEGMNRSVKNDTTSNVANLISDQFFEKNVQYIDLKKLRGNMSDYITNLESPF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ipgB2 mutant had entry into polarized cells reduced by 70% compared to the wild-type (Hachani et al., 2008).
References
Hachani et al., 2008: Hachani A, Biskri L, Rossi G, Marty A, Ménard R, Sansonetti P, Parsot C, Van Nhieu GT, Bernardini ML, Allaoui A. IpgB1 and IpgB2, two homologous effectors secreted via the Mxi-Spa type III secretion apparatus, cooperate to mediate polarized cell invasion and inflammatory potential of Shigella flexenri. Microbes and infection / Institut Pasteur. 2008; 10(3); 260-268. [PubMed: 18316224].