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mxiD from Shigella flexneri 2a str. 301

Victor ID 906
Gene Name mxiD from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1238034
NCBI Protein GI 31983567
Locus Tag CP0145
Protein Accession NP_858278.1
Other Database IDs UniProtKB-ID: MXID_SHIFL
UniRef100: UniRef100_Q04641
UniRef90: UniRef90_Q04641
UniRef50: UniRef50_Q04641
UniParc: UPI000012FAAC
EMBL: X67206
EMBL: AL391753
EMBL: AF348706
EMBL: AF386526
EMBL-CDS: CAA47644.1
EMBL-CDS: CAC05820.1
EMBL-CDS: AAK18464.1
EMBL-CDS: AAL72331.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
PDB: 2JW1
DIP: DIP-45187N
EnsemblGenome: EBESCG00000093062
EnsemblGenome_TRS: EBESCT00000094018
EnsemblGenome_PRO: EBESCP00000090225
GenomeReviews: AF386526_GR
KEGG: sfl:CP0145
HOGENOM
Taxonomy ID 198214
Plasmid No pCP301
Gene Starting Position 123949
Gene Ending Position 125649
Gene Strand (Orientation) +
Protein Name MxiD, outermembrane protein of the secretin family, component of the Mxi-Spa secretion machinery
DNA Sequence 
>gi|31983523:123949-125649 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence
AATGAAAAAATTTAATATTAAATCTTTGACTCTCTTGATTGTATTGTTACCATTGATAGTTAATGCTAAT
AATATTGACTCTCATTTATTAGAACAAAATGACATAGCGAAATATGTTGCTCAAAGTGATACGGTAGGAT
CTTTTTTTGAACGTTTTTCTGCGTTATTAAATTATCCTATTGTTGTTAGCAAACAAGCTGCAAAAAAGAG
AATATCTGGGGAGTTTGATTTATCTAATCCAGAAGAAATGCTTGAAAAGCTGACATTACTTGTGGGACTC
ATATGGTATAAAGATGGAAATGCATTATACATATATGACTCTGGAGAATTAATAAGCAAAGTTATTTTGC
TGGAGAATATATCACTTAATTATCTTATTCAGTATCTGAAGGATGCTAACCTTTATGATCACAGATATCC
TATAAGAGGAAACATTAGTGATAAAACATTCTATATATCTGGTCCTCCGGCATTGGTTGAACTGGTAGCT
AATACAGCAACTTTGCTTGATAAGCAGGTTTCTTCTATTGGGACAGATAAAGTTAATTTTGGGGTTATAA
AATTAAAAAATACATTTGTTAGTGACAGAACTTATAATATGAGAGGGGAGGATATTGTCATCCCAGGGGT
GGCTACTGTTGTAGAACGTTTATTAAATAATGGTAAGGCTCTGAGTAACAGACAAGCCCAAAATGATCCG
ATGCCACCCTTTAATATTACACAGAAAGTATCTGAGGATAGTAATGACTTTTCATTTAGTTCAGTTACCA
ATAGTTCTATATTAGAGGATGTATCACTTATTGCATATCCAGAAACCAATTCTATATTAGTCAAAGGTAA
TGATCAGCAAATACAGATTATTCGCGATATTATCACTCAGTTAGATATAGCCAAACGACATATAGAATTA
TCATTATGGATAATCGATATTGATAAATCTGAATTAAATAACCTTGGTGTTAATTGGCAAGGAACGGCTT
CATTTGGTGATTCGTTTGGTGCGTCATTTAATATGAGCTCATCAGCATCGATAAGCACTTTGGACGGCAA
TAAGTTTATTGCTTCAGTTATGGCATTAAATCAGAAAAAGAAAGCAAATGTAGTTTCAAGGCCGGTGATT
TTGACACAAGAGAATATTCCGGCTATATTTGATAATAACAGGACTTTTTATGTGTCATTAGTTGGTGAGC
GCAATTCTTCGTTGGAGCATGTTACGTATGGAACATTGATAAATGTTATACCTCGCTTTTCATCTCGGGG
ACAAATTGAGATGTCTTTAACGATAGAGGATGGAACAGGAAATAGTCAGTCAAATTACAATTATAATAAT
GAAAATACATCTGTCCTTCCAGAAGTTGGAAGGACCAAAATCAGTACAATAGCGAGAGTTCCACAAGGCA
AAAGTTTGTTGATAGGTGGTTATACGCATGAAACGAACTCTAACGAAATAATATCTATTCCTTTTCTCTC
CTCTATTCCTGTAATCGGTAATGTGTTCAAGTATAAAACAAGTAATATCAGTAATATTGTAAGGGTTTTT
CTGATTCAACCCCGTGAGATAAAGGAGTCAAGTTATTATAATACTGCAGAATATAAAAGCCTCATATCTG
AAAGAGAAATACAAAAGACTACACAAATAATCCCATCTGAAACTACTTTGCTGGAAGACGAAAAATCATT
GGTTTCATACTTAAATTACTA
Protein Sequence 
>gi|31983567|ref|NP_858278.1| outermembrane protein MxiD [Shigella flexneri 2a str. 301] MKKFNIKSLTLLIVLLPLIVNANNIDSHLLEQNDIAKYVAQSDTVGSFFERFSALLNYPIVVSKQAAKKRISGEFDLSNPEEMLEKLTLLVGLIWYKDGNALYIYDSGELISKVILLENISLNYLIQYLKDANLYDHRYPIRGNISDKTFYISGPPALVELVANTATLLDKQVSSIGTDKVNFGVIKLKNTFVSDRTYNMRGEDIVIPGVATVVERLLNNGKALSNRQAQNDPMPPFNITQKVSEDSNDFSFSSVTNSSILEDVSLIAYPETNSILVKGNDQQIQIIRDIITQLDIAKRHIELSLWIIDIDKSELNNLGVNWQGTASFGDSFGASFNMSSSASISTLDGNKFIASVMALNQKKKANVVSRPVILTQENIPAIFDNNRTFYVSLVGERNSSLEHVTYGTLINVIPRFSSRGQIEMSLTIEDGTGNSQSNYNYNNENTSVLPEVGRTKISTIARVPQGKSLLIGGYTHETNSNEIISIPFLSSIPVIGNVFKYKTSNISNIVRVFLIQPREIKESSYYNTAEYKSLISEREIQKTTQIIPSETTLLEDEKSLVSYLNY
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiD mutant is unable to invade HeLa cells or to provoke keratoconjunctivitis in guinea-pigs (Allaoui et al., 1993).
COG COG1450NU, under N: Cell motility; U: Intracellular trafficking, secretion, and vesicular transport
References
Allaoui et al., 1993: Allaoui A, Sansonetti PJ, Parsot C. MxiD, an outer membrane protein necessary for the secretion of the Shigella flexneri lpa invasins. Molecular microbiology. 1993; 7(1); 59-68. [PubMed: 8437520].