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mxiE from Shigella flexneri 2a str. 301

Victor ID 905
Gene Name mxiE from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1238033
NCBI Protein GI 31983566
Locus Tag CP0144
Protein Accession NP_858277.1
Other Database IDs UniProtKB-ID: MXIE_SHIFL
UniRef100: UniRef100_P0A2S7
UniRef90: UniRef90_P0A2S7
UniRef50: UniRef50_P0A2S7
UniParc: UPI000012FAAE
EMBL: X67206
EMBL: AL391753
EMBL: AF348706
EMBL: AY206439
EMBL: AF386526
EMBL-CDS: CAA47643.1
EMBL-CDS: CAC05819.1
EMBL-CDS: AAK18463.1
EMBL-CDS: AAP79007.1
EMBL-CDS: AAL72330.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093256
EnsemblGenome_TRS: EBESCT00000094212
EnsemblGenome_PRO: EBESCP00000090419
GenomeReviews: AF386526_GR
KEGG: sfl:CP01
Taxonomy ID 198214
Plasmid No pCP301
Gene Starting Position 123330
Gene Ending Position 123962
Gene Strand (Orientation) +
Protein Name MxiE, similarities to transcriptional activators of the AraC family, function unknown
DNA Sequence 
>gi|31983523:123330-123962 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence
CATGGAAGGGTTTTTTTTTGTCCGAAATCAAAATATAAAATTCAGTGATAATGTGAACTATCATTATCGC
TTTAACATTAATAGTTGTGCAAAATTTCTTGCTTTTTGGGACTATTTCAGTGGTGCTCTAGTAGAGCATA
GCCATGCTGAAAAATGTATTCATTTCTATCATGAGAATGATCTTCGGGATAGTTGTAATACCGAATCGAT
GCTTGATAAGTTAATGTTAAGATTCATCTTTTCATCTGACCAGAATGTAAGTAATGCACTGGCTATGATA
CGAATGACTGAGTCATATCATTTGGTTCTTTATCTTCTGAGAACTATTGAGAAAGAAAAGGAGGTAAGAA
TAAAGAGTCTGACAGAGCATTATGGTGTGTCGGAGGCTTATTTTAGATCTTTATGTAGAAAAGCTTTAGG
GGCAAAAGTCAAAGAACAACTGAACACTTGGCGGTTAGTAAATGGTTTATTAGATGTATTTTTGCACAAT
CAAACAATCACTTCAGCTGCCATGAATAATGGGTATGCATCAACATCCCATTTTTCAAATGAGATAAAAA
CACGACTAGGCTTTTCTGCAAGAGAATTATCGAATATTACTTTTTTAGTGAAAAAAATAAATGAAAAAAT
TTA
Protein Sequence 
>gi|31983566|ref|NP_858277.1| AraC-like family protein MxiE [Shigella flexneri 2a str. 301] MEGFFFVRNQNIKFSDNVNYHYRFNINSCAKFLAFWDYFSGALVEHSHAEKCIHFYHENDLRDSCNTESMLDKLMLRFIFSSDQNVSNALAMIRMTESYHLVLYLLRTIEKEKEVRIKSLTEHYGVSEAYFRSLCRKALGAKVKEQLNTWRLVNGLLDVFLHNQTITSAAMNNGYASTSHFSNEIKTRLGFSARELSNITFLVKKINEKI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiE deletion mutants are unable to block apoptosis of host epithelial cells (Clark and Maurelli, 2007).
COG COG2207K, under K: Transcription
References
Clark and Maurelli, 2007: Clark CS, Maurelli AT. Shigella flexneri inhibits staurosporine-induced apoptosis in epithelial cells. Infection and immunity. 2007; 75(5); 2531-2539. [PubMed: 17339354].