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mxiJ from Shigella flexneri 2a str. 301

Victor ID 903
Gene Name mxiJ from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1238031
NCBI Protein GI 31983564
Locus Tag CP0139
Protein Accession NP_858272.1
Other Database IDs UniProtKB-ID: MXIJ_SHIFL
UniRef100: UniRef100_Q06081
UniRef90: UniRef90_Q06081
UniRef50: UniRef50_Q06081
UniParc: UPI000012FAB2
EMBL: M98390
EMBL: AL391753
EMBL: AF348706
EMBL: AF386526
EMBL-CDS: AAA26532.1
EMBL-CDS: CAC05814.1
EMBL-CDS: AAK18458.1
EMBL-CDS: AAL72328.1
RefSeq_NT: NC_002698.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093164
EnsemblGenome_TRS: EBESCT00000094120
EnsemblGenome_PRO: EBESCP00000090327
GenomeReviews: AF386526_GR
KEGG: sfl:CP0139
HOGENOM: HBG671305
OMA: HISVIAI
P
Taxonomy ID 198214
Plasmid No pCP301
Gene Starting Position 120502
Gene Ending Position 121227
Gene Strand (Orientation) +
Protein Name MxiJ, lipoprotein, component of the Mxi-Spa secretion machinery
DNA Sequence 
>gi|31983523:120502-121227 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence
TATGATTAGGTATAAAGGTTTTATTTTATTCTTGTTGCTGATGTTGATTGGATGTGAGCAACGTGAAGAG
TTAATTTCTAATTTATCTCAAAGACAGGCAAATGAAATAATATCTGTGCTAGAACGCCATAATATTACTG
CTAGAAAAGTTGATGGAGGTAAACAGGGGATCTCGGTACAAGTCGAAAAGGGGACATTTGCATCGGCAGT
TGATTTGATGCGCATGTACGATTTGCCAAATCCGGAGAGAGTTGATATCTCACAAATGTTTCCTACAGAT
TCATTAGTGTCTTCTCCAAGAGCTGAAAAGGCCCGTTTATATAGTGCTATTGAGCAACGGCTGGAACAGT
CTTTAGTTTCTATTGGTGGTGTTATTTCGGCAAAAATACATGTTAGCTATGATCTTGAAGAAAAAAATAT
ATCTTCAAAACCGATGCATATATCAGTAATCGCTATATATGACTCACCGAAAGAGTCTGAACTATTAGTT
AGTAATATTAAGCGATTTTTGAAAAACACCTTTTCTGATGTTAAGTATGAAAATATATCTGTCATATTAA
CTCCGAAAGAAGAATATGTTTATACAAATGTACAACCTGTTAAGGAAGTTAAATCGGAATTTTTAACAAA
TGAAGTAATATATTTATTTCTCGGGATGGCTGTACTAGTTGTCATTCTTTTGGTATGGGCATTCAAAACA
GGGTGGTTCAAGAGAAACAAAATATG
Protein Sequence 
>gi|31983564|ref|NP_858272.1| Mxi-Spa secretion machinery protein MxiJ [Shigella flexneri 2a str. 301] MIRYKGFILFLLLMLIGCEQREELISNLSQRQANEIISVLERHNITARKVDGGKQGISVQVEKGTFASAVDLMRMYDLPNPERVDISQMFPTDSLVSSPRAEKARLYSAIEQRLEQSLVSIGGVISAKIHVSYDLEEKNISSKPMHISVIAIYDSPKESELLVSNIKRFLKNTFSDVKYENISVILTPKEEYVYTNVQPVKEVKSEFLTNEVIYLFLGMAVLVVILLVWAFKTGWFKRNKI
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiJ mutant was unable to invade HeLa cells, to induce the formation of plaques on confluent monolayers of HeLa cells, and to provoke keratoconjunctivitis in guinea pigs (Allaoui et al., 1992).
COG COG4669U, under U: Intracellular trafficking, secretion, and vesicular transport
References
Allaoui et al., 1992: Allaoui A, Sansonetti PJ, Parsot C. MxiJ, a lipoprotein involved in secretion of Shigella Ipa invasins, is homologous to YscJ, a secretion factor of the Yersinia Yop proteins. Journal of bacteriology. 1992; 174(23); 7661-7669. [PubMed: 1332940].