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mxiK from Shigella flexneri 2a str. 301

Victor ID 902
Gene Name mxiK from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1238030
NCBI Protein GI 31983563
Locus Tag CP0140
Protein Accession NP_858273.1
Other Database IDs UniProtKB-ID: MXIK_SHIFL
UniRef100: UniRef100_P0A227
UniRef90: UniRef90_P0A227
UniRef50: UniRef50_P0A227
UniParc: UPI000012FAB4
EMBL: AL391753
EMBL: AF348706
EMBL: AF386526
EMBL: M98390
EMBL-CDS: CAC05815.1
EMBL-CDS: AAK18459.1
EMBL-CDS: AAL72327.1
EMBL-CDS: AAA26533.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093124
EnsemblGenome_TRS: EBESCT00000094080
EnsemblGenome_PRO: EBESCP00000090287
GenomeReviews: AF386526_GR
KEGG: sfl:CP0140
HOGENOM: HBG210273
OMA: VGVYERI
ProtClustDB: CLSK505052
Taxonomy ID 198214
Plasmid No pCP301
Gene Starting Position 121224
Gene Ending Position 121751
Gene Strand (Orientation) +
Protein Name MxiK, putative component of the Mxi-Spa secretion machinery
DNA Sequence 
>gi|31983523:121224-121751 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence
TATGATAAGAATGGATGGAATTTATAAAAAATATCTTTCAATAATTTTTGATCCAGCGTTCTATATAAAT
AGAAATCGGTTGAATTTGCCTTCTGAACTGTTAGAAAATGGCGTAATCAGAAGTGAGATTAATAATCTCA
TAATTAATAAATATGATCTAAATTGCGATATTGAACCTTTAAGCGGGGTAACCGCTATGTTTGTTGCCAA
CTGGAATTTACTTCCAGCTGTTGCTTATTTTATCGGTAGTCAAGAGTCTCGGTTAATTAATCATAGTGAG
ATGGTTATTAGTTATTATGGGGGCAAAATCAGTAAGCAAGGGGAGGCCGCTATTCGAAGTGGTTTTTGGC
ATCTTATTGCGTGGAAGGAAAATATATCTGTTGGTATATATGAAAGAATAAACTTATTATTTAATCCAAT
TGCTTTGGAGGGAAATTATACGCCTGTAGAAAGAAATTTGTCCCGATTAAATGAAGGTATGCAATATGCA
AAAAGGCACTTTACCGGTATCCAGACATCATGCCTATG
Protein Sequence 
>gi|31983563|ref|NP_858273.1| Mxi-Spa secretion machinery protein MxiK [Shigella flexneri 2a str. 301] MIRMDGIYKKYLSIIFDPAFYINRNRLNLPSELLENGVIRSEINNLIINKYDLNCDIEPLSGVTAMFVANWNLLPAVAYFIGSQESRLINHSEMVISYYGGKISKQGEAAIRSGFWHLIAWKENISVGIYERINLLFNPIALEGNYTPVERNLSRLNEGMQYAKRHFTGIQTSCL
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiK mutants are unable to invade HeLa cells (Jouihri et al., 2003).
References
Jouihri et al., 2003: Jouihri N, Sory MP, Page AL, Gounon P, Parsot C, Allaoui A. MxiK and MxiN interact with the Spa47 ATPase and are required for transit of the needle components MxiH and MxiI, but not of Ipa proteins, through the type III secretion apparatus of Shigella flexneri. Molecular microbiology. 2003; 49(3); 755-767. [PubMed: 12864857].