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mxiN from Shigella flexneri 2a str. 301

Victor ID 900
Gene Name mxiN from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1238027
NCBI Protein GI 56404016
Locus Tag CP0141
Protein Accession NP_858274.2
Other Database IDs UniProtKB-ID: Q99PY0_SHIFL
UniRef100: UniRef100_Q7BEL9
UniRef90: UniRef90_Q3YTN9
UniRef50: UniRef50_Q3YTN9
UniParc: UPI00000B1827
EMBL: AF386526
EMBL: AL391753
EMBL-CDS: AAL72324.2
EMBL-CDS: CAC05816.1
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093157.
EnsemblGenome_TRS: EBESCT00000094113
EnsemblGenome_PRO: EBESCP00000090320
GenomeReviews: AF386526_GR
KEGG: sfl:CP0141
HOGENOM: HBG683614
OMA: DERIIST
ProtClustDB: CLSK505053
Taxonomy ID 198214
Plasmid No pCP301
Gene Starting Position 121693
Gene Ending Position 122388
Gene Strand (Orientation) +
Protein Name MxiN, putative component of the Mxi-Spa secretion machinery
DNA Sequence 
>gi|31983523:121693-122388 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence
AATGAAGGTATGCAATATGCAAAAAGGCACTTTACCGGTATCCAGACATCATGCCTATGATGGTGTTGTT
ATAAAGAGAATTGAAAAGGAATTATGTAAAACCATAAAAGATAGAGACACTGAGAGTAAGAAGAAAGCAA
TTTGTGTTATAAAGGAGGCTACGAAAAAAGCTGAATCACTGCGTATAGATGCTGTATGTGATGGTTATCA
AATTGGTATACAGACTGCTTTTGAGCATATTATTGACTATATTTGTGAATGGAAGTTAAAGCAAAATGAA
AATAGAAGAAATATTGAGGACTATATAACTAGTTTGCTTTCAGAAAATTTACATGATGAGAGGATCATTA
GCACTTTATTGGAGCAGTGGCTTAGTTCGTTGCGTAATACAGTAACAGAATTAAAAGTGGTTTTGCCCAA
GTGTAATTTAGCACTGAGGAAAAAGTTAGAACTTGATCTCCATAAATATCGCTCAGATGTCAAGATTATT
TTAAAATATTCTGAAGGGAATAATTATATATTCTGTAGTGGTAATCAAGTAGTGGAGTTTAGTCCTCAGG
ATGTAATATCAGGTGTTAAAATAGAACTTGCGGAAAAATTAACAAAAAATGATAAAAAATATTTCAAAGA
GTTAGCACATAAGAAACTGAGACAAATTGCAGAAGACTTGTTAAAAGAGAATCCTGTTAATGATTA
Protein Sequence 
>gi|56404016|ref|NP_858274.2| Mxi-Spa secretion machinery protein MxiN [Shigella flexneri 2a str. 301] MKVCNMQKGTLPVSRHHAYDGVVIKRIEKELCKTIKDRDTESKKKAICVIKEATKKAESLRIDAVCDGYQIGIQTAFEHIIDYICEWKLKQNENRRNIEDYITSLLSENLHDERIISTLLEQWLSSLRNTVTELKVVLPKCNLALRKKLELDLHKYRSDVKIILKYSEGNNYIFCSGNQVVEFSPQDVISGVKIELAEKLTKNDKKYFKELAHKKLRQIAEDLLKENPVND
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: mxiN mutants were unable to invade HeLa cells (Jouihri et al., 2003).
References
Jouihri et al., 2003: Jouihri N, Sory MP, Page AL, Gounon P, Parsot C, Allaoui A. MxiK and MxiN interact with the Spa47 ATPase and are required for transit of the needle components MxiH and MxiI, but not of Ipa proteins, through the type III secretion apparatus of Shigella flexneri. Molecular microbiology. 2003; 49(3); 755-767. [PubMed: 12864857].