Search: for Help
About
Introduction
Statistics
Your PHIDIAS
Register or Login
Philert
Submission
Curated Data
Victors
BBP (Brucella)
Phinfo
Phinet
HazARD
Data Analysis
Phigen
Pacodom
BLAST
Help & Documents
Documents
FAQs
Links
Acknowledgements
Disclaimer
Contact Us
UMMS Logo

virF from Shigella flexneri 2a str. 301

Victor ID 897
Gene Name virF from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1238022
NCBI Protein GI 56404005
Locus Tag CP0046
Protein Accession NP_858179.2
Other Database IDs UniProtKB-ID: VIRF_SHIFL
UniRef100: UniRef100_P0A2T2
UniRef90: UniRef90_P0A2T2
UniRef50: UniRef50_P0A2T2
UniParc: UPI0000138851
EMBL: M29172
EMBL: X16661
EMBL: AL391753
EMBL: AF348706
EMBL: AY206433
EMBL: AF386526
EMBL-CDS: AAA26545.1
EMBL-CDS: CAA34648.1
EMBL-CDS: CAC05780.1
EMBL-CDS: AAK18362.1
EMBL-CDS: AAP78977.1
EMBL-CDS: AAL72294.2
RefSeq_NT: NC_004851.1
EnsemblGenome: EBESCG00000093054
EnsemblGenome_TRS: EBESCT00000094010
EnsemblGenome_PRO: EBESCP00000090217
GenomeReviews: AF386526_GR
KEG
Taxonomy ID 198214
Plasmid No pCP301
Gene Starting Position 36448
Gene Ending Position 37236
Gene Strand (Orientation) -
Protein Name VirF, member of the AraC family of transcriptional activators, required for transcription of virB and icsA
DNA Sequence 
>gi|31983523:36448-37236 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence
TTTAAAATTTTTTATGATATAAGTAAAATTTCTTTGGAGTTATACCATAATATTCATTAAATTTCCTTAT
AAAATAAGATGGGCTTGATATTCCGATAAGTCTTGATACATCATTAATATAGCTTTGACTATTCAATAAA
AGCTTTGCTGCATGATGCATGCGAATATCAAGAAGGATTTGTTGAAATGTTAATTTTTCACTCTCCAATC
GTTTTCTAACAGCTATTTCTGATAAATTCAAGTTATTTGAAATATCAGAAAGACGCCATCTCTTCTCGAT
GTTTTTTTCAACAATCTTCCTTATCTGATCAGAAAAACTAAGAGAAGAAGCTATCGATATCGAAGTATAT
AAAGCTTCCTCATCAGAAACAGCTGATAAAAGGCAAGCTAAACTATAGATCTTTCTTTTGCCGAAAGGCA
TCTCTTTTATAGATTTGAACAAATCGATAGAAACCTCCTCCTCAGAGAGGAGGAATATTTTTTTGTTTAA
CCCCCTTTTCTCCTCAGAATAGGAGTGTTGAAATGAATAAATTGGTTCCATTATTCTAATAATGCTTAAT
AATAAATTTCTGTCAAGGCTTATAATCTCAAATGGATTAATGCTATCAGATTTTTTTATGGAGACGTTTA
TTTGTATATTTCGCTCTATAAAAGCAATTTGCCCTTCATCGATAGTCAAAGTTTCATTGCCTGAGCTAAC
CGTCATTGAACACCTTTTTGCATATAAAATAATATAGTTATGCAAGCGAACCTTTATATCTATTTTGTTT
TTATGTCCCATATCCATCA
Protein Sequence 
>gi|56404005|ref|NP_858179.2| transcriptional activator VirF [Shigella flexneri 2a str. 301] MMDMGHKNKIDIKVRLHNYIILYAKRCSMTVSSGNETLTIDEGQIAFIERNIQINVSIKKSDSINPFEIISLDRNLLLSIIRIMEPIYSFQHSYSEEKRGLNKKIFLLSEEEVSIDLFKSIKEMPFGKRKIYSLACLLSAVSDEEALYTSISIASSLSFSDQIRKIVEKNIEKRWRLSDISNNLNLSEIAVRKRLESEKLTFQQILLDIRMHHAAKLLLNSQSYINDVSRLIGISSPSYFIRKFNEYYGITPKKFYLYHKKF
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: virF knockouts are non-invasive to host cells (Hurt et al., 2010).
COG COG2207K, under K: Transcription
References
Hurt et al., 2010: Hurt JK, McQuade TJ, Emanuele A, Larsen MJ, Garcia GA. High-throughput screening of the virulence regulator VirF: a novel antibacterial target for shigellosis. Journal of biomolecular screening : the official journal of the Society for Biomolecular Screening. 2010; 15(4); 379-387. [PubMed: 20237205].