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ospF from Shigella flexneri 2a str. 301

Victor ID 894
Gene Name ospF from Shigella flexneri 2a str. 301
Sequence Strain (Species/Organism) Shigella flexneri 2a str. 301
NCBI Gene ID 1238011
NCBI Protein GI 31983551
Locus Tag CP0010
Protein Accession NP_858143.1
Other Database IDs UniProtKB-ID: OSPF_SHIFL
UniRef100: UniRef100_Q8VSP9
UniRef90: UniRef90_Q31SR9
UniRef50: UniRef50_Q327I2
UniParc: UPI00000BB94A
EMBL: AL391753
EMBL: AF348706
EMBL: AY206429
EMBL: AY879342
EMBL: AF386526
EMBL: DQ362850
EMBL: DQ362864
EMBL: DQ362865
EMBL: DQ362866
EMBL: DQ362867
EMBL: DQ362868
EMBL: DQ362869
EMBL: DQ362870
EMBL-CDS: CAC05773.1
EMBL-CDS: AAK18324.1
EMBL-CDS: AAP78969.1
EMBL-CDS: AAW64770.1
EMBL-CDS: AAL72315.1
EMBL-CDS: ABD37257.1
EMBL-CDS: ABD37271.1
EMBL-CDS: ABD37272.1
EMBL-CDS:
Taxonomy ID 198214
Plasmid No pCP301
Gene Starting Position 9575
Gene Ending Position 10294
Gene Strand (Orientation) -
Protein Name OspF
DNA Sequence 
>gi|31983523:9575-10294 Shigella flexneri 2a str. 301 plasmid pCP301, complete sequence
TCTACTCTATCATCAAACGATAAAATGGTTCCTCTCGTAACATTTGCTCTTGCCTTTCACTTCCATCTCG
ATCGCTTCGTAGTTCATTACGATAGCTGACATATTTCCAGTCTTCAGGTCTAACATCTGACGCCGGATAC
TCCCCGGGAGCGATTTTGCTTCTTAATAGATTAGACTCGAGACACATTATAAATTGTCGTATTTTATGAA
GTAATAAAGCACTATATTGCGAGCATTCCTGATCTGATTTTACATATAGCGTAAACTGAGCTCCTATCCC
CACACGAGATTGCTGAGAAACTCGATTCATATCAGTTATCTTCCATTTATCTATAGGACTGTCCTCTGAA
AATAATAAACCAGACAAAATTTGGAATGCCAGAGGAACTTGCTCCCTAGCTATACTAATATGAAACTTGT
CCCCAACAAAATCCCCCTTACTCTGAGGATTTTCACGACATGCATGAATAAACACATCTCCACTATGGTT
CACAATCTGGAATCCTTGGTACATGACAGAAAAAGATTGACATATATCAGAGTAAGTTGGCACGTTCGAT
GCTACTTTGAAATAGTACGCTGGGTATTGCCGTATTTGGTTGTACAATATATTGAAGTTATTTTTCAATC
TTTCATTCGCAGAAAGCATCTGCGGTATTTCAGACCTCACAACATTCAAAGAATCTAAATTTAGTTTTAG
ACAGGGCTTTTTTATGGGCA
Protein Sequence 
>gi|31983551|ref|NP_858143.1| OspF [Shigella flexneri 2a str. 301] MPIKKPCLKLNLDSLNVVRSEIPQMLSANERLKNNFNILYNQIRQYPAYYFKVASNVPTYSDICQSFSVMYQGFQIVNHSGDVFIHACRENPQSKGDFVGDKFHISIAREQVPLAFQILSGLLFSEDSPIDKWKITDMNRVSQQSRVGIGAQFTLYVKSDQECSQYSALLLHKIRQFIMCLESNLLRSKIAPGEYPASDVRPEDWKYVSYRNELRSDRDGSERQEQMLREEPFYRLMIE
Molecule Role Virulence factor
Molecule Role Annotation MUTATION: ospF mutants had reduced PMN transepithelial migration when compared to wild-type infection, PMN transepithelial migration is necessary for virulence of Shigella (Zurawski et al., 2006).
References
Zurawski et al., 2006: Zurawski DV, Mitsuhata C, Mumy KL, McCormick BA, Maurelli AT. OspF and OspC1 are Shigella flexneri type III secretion system effectors that are required for postinvasion aspects of virulence. Infection and immunity. 2006; 74(10); 5964-5976. [PubMed: 16988276].